Cardiotoxicity of 5-fluorouracil: Two cases with severe bradycardia and review of the literature

We, herein, report two cases one with bradycardia and the other with angina following bradycardia during the course of cisplatin and 5-fluorouracil treatment.

📌 3 Key Takeaways

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Objective & Hypothesis:Cardiotoxicity of 5-fluorouracil including ECG changes and angina pectoris have been previously well defined.

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Key Findings & Data:However, cisplatin related cardiotoxicity has been reported rarely.

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Conclusion & Impact:We, herein, report two cases one with bradycardia and the other with angina following bradycardia during the course of cisplatin and 5-fluorouracil treatment.

🔬Design:Research Article

📍Scope:Comprehensive Sample

⚙️Variables:Florourasil · Elektrokardiyografi · İlaç tedavisi

Abstract

Cardiotoxicity of 5-fluorouracil including ECG changes and angina pectoris have been previously well defined. However, cisplatin related cardiotoxicity has been reported rarely. We, herein, report two cases one with bradycardia and the other with angina following bradycardia during the course of cisplatin and 5-fluorouracil treatment.

Keywords

Florourasil Elektrokardiyografi İlaç tedavisi Antineoplastik ajanlar Anjina pektoris Sisplatin Fluorouracil Electrocardiography Drug Therapy Antineoplastic Agents Angina Pectoris Cisplatin

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Cite This Article

SAMUR, M., ARICAN, A., ÇAKIR, M., ŞENCAN, O., DEMİRKAZIK, A., AKBULUT, H., İÇLİ, F. (1999). Cardiotoxicity of 5-fluorouracil: Two cases with severe bradycardia and review of the literature. Turkish Journal of Cancer, Cilt: 29 - Sayı: 1, 39–41. https://ajindex.com/articles/368415