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Journals / Toraks Dergisi / 2006 / Cilt: 7 - Sayı: 3

The role of 18F-FDG-PET in staging for the surgery of non-small cell lung cancer

Küçük hücreli dışı akciğer kanseri cerrahisinde 18F-FDG-PET'in evrelemedeki yeri

Levent CANSEVER
Gökhan HACIİBRAHİMOĞLU
Celalettin KOCATÜRK
Kerim SÖNMEZOĞLU
Mehmet Ali BEDİRHAN
Pages
145–150
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

According to the results of thorax CT, 8 (38.1%) cases remained at the same stage, while 9 (42.8%) cases were down-staged and 4 (19.1%) cases were up-staged.

📌 3 Key Takeaways

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Objective & Hypothesis:Among the patients who were operated with the diagnosis of NSCLC between January 2003-May 2004, 21 cases who had 18F-FDG-PET examination were included in this study.
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Key Findings & Data:The results of the thorax CT and the 18F-FDG-PET were compared with the postoperative pathologies.
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Conclusion & Impact:According to the results of thorax CT, 8 (38.1%) cases remained at the same stage, while 9 (42.8%) cases were down-staged and 4 (19.1%) cases were up-staged.
🔬Design:Research Article
📍Scope:2003 Verileri
⚙️Variables:Karsinom · küçük hücreli dışı akciğer · Neoplazm evrelendirilmesi

Abstract

Among the patients who were operated with the diagnosis of NSCLC between January 2003-May 2004, 21 cases who had 18F-FDG-PET examination were included in this study. The results of the thorax CT and the 18F-FDG-PET were compared with the postoperative pathologies. In two cases, the sensitivity of CT was 60%, the specificity was 75%, the positive predictive value was 42.8%, the negative predictive value 85.7%, and the accuracy was 71.4%. At the 18F-FDG-PET studies, the sensitivity was 100%, the specificity was 75%, the positive predictive value was 55.5%, the negative predictive value 100%, and the accuracy was 80.9%. CT and 18F-FDG-PET staging was compared with pathological staging. The numbers of the cases remaining at the same stage, being downstaged or up-staged were determined. According to the results of thorax CT, 8 (38.1%) cases remained at the same stage, while 9 (42.8%) cases were down-staged and 4 (19.1%) cases were up-staged. The comparison of 18F-FDG-PET results with histopathological results revealed that 14 (66.6%) cases remained at the same stage, while 4 (19.1%) cases were up-staged and 3 (14.3%) were down-staged. In conclusion, 18FFDG- PET is a reliable method with its high negative predictive value for the systematic evaluation of lung cancer and the staging of the mediastinum.

Özet

Ocak 2003-Mayıs 2004 tarihleri arasında küçük hücreli dışı akciğer kanseri (KHDAK) nedeniyle opere edilen olgulardan 18F-FDG-PET tetkiki olan 21 olgu çalışmaya alındı. Postoperatif patolojiler ile BT ve 18F-FDG-PET sonuçları karşılaştırıldı. N2 olgularında BT�nin duyarlılığı %60, özgüllüğü %75, pozitif prediktif değer %42.8, negatif prediktif değer %85.7 ve doğruluk oranı %71.4 olarak bulundu. 18F-FDG-PET tetkikindeyse duyarlılık %100, özgüllük %75, pozitif prediktif değer %55.5, negatif prediktif değer %100 ve doğruluk oranı %80.9 olarak saptandı. Patolojik evrelendirme ile BT ve 18F-FDG-PET evrelemeleri karşılaştırıldı. Aynı evrede kalanların sayısı, evresi düşenlerin sayısı (down-stage) ve evresi yükselenlerin sayısı (up-stage) tespit edildi. Toraks BT, 8 (%38.1) olguda aynı evrede, 9 (%42.8) olguda düşük evre (up-stage) ve 4 (%19.1) olguda ise yüksek evre (down-stage) olarak bildirmiştir. 18F-FDG-PET sonuçlarındaysa, evresi değişmeyen olgu sayısı 14 (%66.6) olarak tespit edildi. 18F-FDGPET�te yüksek evre (down-stage) tespit edilen olgu sayısı 4 (%19.1), daha düşük evre (up-stage) tespit edilen olgu sayısıysa 3 (%14.3) olarak bulundu. Sonuç olarak, 18F-FDG-PET, akciğer kanseri cerrahisinde sistemik taramalarda ve mediyasten evrelemesindeki yüksek negatif prediktif değeriyle güvenilir bir yöntemdir.

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Cite This Article

CANSEVER, L., HACIİBRAHİMOĞLU, G., KOCATÜRK, C., SÖNMEZOĞLU, K., BEDİRHAN, M. A. (2006). The role of 18F-FDG-PET in staging for the surgery of non-small cell lung cancer. Toraks Dergisi, Cilt: 7 - Sayı: 3, 145–150. https://ajindex.com/articles/368223

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