Journals / Toraks Dergisi / 2002 / Cilt: 3 - Sayı: 2

CT in differantial diagnosis of diffuse pleural disease

Diffüz plevral hastalıkların ayırıcı tanısında bilgisayarlı tomografi

Pages
138–145
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

We conclud that CT is helpful in the differential diagnosis of diffuse pleural diseases, particularly in differentiating malign from benign conditions and metastatic pleural disease from malignant mesothelioma.

📌 3 Key Takeaways

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Objective & Hypothesis:The CT appearances of benign and malign pleural diseases have been well described.
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Key Findings & Data:Without knowledge of clinical or pathologic data , we reviewed CT findings in 146 consecutive patients with proved diffuse pleural disease. 59 of the patients had malign , 87 of them had benign pleural diseases.
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Conclusion & Impact:We conclud that CT is helpful in the differential diagnosis of diffuse pleural diseases, particularly in differentiating malign from benign conditions and metastatic pleural disease from malignant mesothelioma.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Tanı · ayırıcı · Plevra hastalıkları

Abstract

The CT appearances of benign and malign pleural diseases have been well described. However, there have been limited number of reports which assessed features in the differential diagnosis of diffuse pleural disease. Without knowledge of clinical or pathologic data , we reviewed CT findings in 146 consecutive patients with proved diffuse pleural disease. 59 of the patients had malign , 87 of them had benign pleural diseases. The patient group included 95 women and 51 men , aged between 15 and 76 years. CT findings that were helpful in distinguishing malignant from benign pleural disease were: 1) pleural nodularity, 2) rind , 3) bilateral pleural disease, 4) mediastinal pleural involvement, 5) pleural thickening greater than 1 cm ,6) hilar and mediastinal LAP, 7) volume loss. The sensitivities were 37% , 22% , 33% , 30% , 35%, 35% and 27% respectively. The specificities were 96% , 96% , 88% , 88% , 87% , 86% and 86% respectively. CT findings differentiating malignant mesothelioma from metastatic pleural disease were identified. Findings for malignant mesothelioma were as follows: 1) pleural plaque (sensitivity 15% , specificity 100%), 2) interlober fissure involvement (sensitivity 30% , specificity 99%), 3)pleural thickening greater than 1cm (sensitivity 60% , specificity 75%). Wherease , findings for metastatic pleural disease were: 1) lung parenchymal involvement (sensitivity 50%, specificity 100%), 2) mediastinal shift (sensitivity 19%, specificity 100%), 3) mediastinal and hilar LAP (sensitivity 44%, specificity 90%). We conclud that CT is helpful in the differential diagnosis of diffuse pleural diseases, particularly in differentiating malign from benign conditions and metastatic pleural disease from malignant mesothelioma.

Özet

Benign ve malign plevral hastalıklarda BT görünümleri iyi tanımlanmıştır. Bununla beraber, diffüz plevral hastalıkların ayırıcı tanısında bu görünümlerin ayrıntılı şekilde değerlendirildiği çalışma sayısı azdır. Çeşitli yöntemlerle diffüz plevral hastalığı olduğu saptanan 146 hasta üzerinde, klinik veya patolojik verilere sahip olmadan BT bulgularını değerlendirdik. Bu hastalardan 59'unda malign, 87'sinde ise benign plevral hastalık vardı. Çalışmada, yaşları 15 ile 76 arasında değişen 95 kadın ve 51 erkek olgu yer aldı. Malign hastalıkların benign plevral hastalıklardan ayırt edilmesinde yardımcı olan BT bulguları şu şekilde belirlendi: (1) plevral nodülarite, (2) rind, (3) bilateral plevral tutulum, (4) mediastinal plevra tutulumu (5) plevral kalınlığın 1 cm'in üstünde olması, (6) hiler ve mediastinal LAP ve (7) volüm kaybı. Bu bulguların duyarlılıkları, sırasıyla % 37, %22, %33, %30, %35, %35, ve %27, özgüllükleri, sırasıyla %96, %96, %88, %88, %87, %86, %86 olarak bulundu. Malign mezotelyomalar ile metastatik plevral hastalıkları ayırmada yardımcı BT bulguları şu şekilde belirlendi; malign mezotelyoma için belirleyici bulgular : (1) plevral plak varlığı (duyarlılık %15 ,özgüllük %100), (2) interlober fissür tutulumu (duyarlılık %30 , özgüllük %99) ve (3) plevral kalınlığın 1 cm'in üstünde olması (duyarlılık %60, özgüllük %75). Metastatik plevral hastalık için belirleyici kriterler: (1) akciğer parankimi tutulumu (duyarlılık %50, özgüllük % 100), (2) mediastinal yer değiştirme (duyarlılık %19, özgüllük %100) ve (3) mediastinal ve hiler LAP ( duyarlılık %44, özgüllük %90). Sonuç olarak BT'nin diffüz plevral hastalıkların ayırıcı tanısında, özellikle malign ve benign plevral hastalıkları ve metastatik plevral hastalıkla malign mezotelyomayı ayırt etme konusunda yardımcı olabileceği kanısına varıldı.

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Cite This Article

POLAT, G. E., ŞAHİN, N., YILMAZ, M. U., UTKANER, G., YALNIZ, E., SOY, Ö. (2002). CT in differantial diagnosis of diffuse pleural disease. Toraks Dergisi, Cilt: 3 - Sayı: 2, 138–145. https://ajindex.com/articles/368189

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