Journals / Toraks Dergisi / 2005 / Cilt: 6 - Sayı: 1

Predictive and prognostic factors in long term survival of small cell lung cancer

Küçük hücreli akciğer kanserinde uzun dönem sağkalımda prediktif ve prognostik faktörlerin gözden geçirilmesi

Pages
81–84
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

These factors may be used to figure out good or poor prognosis in SCLC patients and to help clinician make appropriate treatment decisions for individuals.

📌 3 Key Takeaways

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Objective & Hypothesis:Small cell lung cancer (SCLC) is an extremely aggressive tumour with a poor clinical course.
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Key Findings & Data:In this study, we presented 3 SCLC patients as long term survivors.
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Conclusion & Impact:These factors may be used to figure out good or poor prognosis in SCLC patients and to help clinician make appropriate treatment decisions for individuals.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Erişkin · Akciğer neoplazmları · Erkek

Abstract

Small cell lung cancer (SCLC) is an extremely aggressive tumour with a poor clinical course. It is however responsive to both chemotherapy and radiotherapy. Some clinical and laboratory parameters can predict response to chemotherapy and long term survival in SCLC. In this study, we presented 3 SCLC patients as long term survivors. We tried to find some prognostic factors that identify long term survivors. We also compared our results with previous studies. We found that performance status, extent of disease and patient’s age were the most important clinical factors in long term survival. Also lactate dehydrogenase (LDH) level was the most important pretreatment laboratory parameter. These factors may be used to figure out good or poor prognosis in SCLC patients and to help clinician make appropriate treatment decisions for individuals.

Özet

Küçük hücreli akciğer kanseri (KHAK) kötü klinik seyirle giden, hızla ilerleyen bir tümördür. Fakat kemoterapi ve radyoterapiye iyi yanıt verir. Bazı klinik veriler ve laboratuvar parametreleri kemoterapiye yanıtı ve uzun dönem sağkalımı değerlendirmede kullanılabilir. Bu çalışmada, KHAK tanısı alan olgularımızdan uzun dönem sağkalımı olan 3 olgu sunuldu. Uzun dönem sağkalımı belirleyecek bazı prognostik faktörler araştırıldı ve sonuçlarımız daha önceki çalışmalarla karşılaştırıldı. Hastalığın yaygınlığının, performans durumunun ve hasta yaşının uzun dönem sağkalımda önemli olduğu görüldü. Ayrıca LDH’nin en önemli laboratuvar parametresi olduğu belirlendi. Bu faktörlerin KHAK’de hastaların prognozunu belirlemede ve klinisyenin hastaya uygun tedavi yaklaşımını seçmesinde yardımcı olabileceği düşünüldü.

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Cite This Article

AYGENCEL, S. G., OĞUZÜLGEN, İ. K., ÖZTÜRK, C. (2005). Predictive and prognostic factors in long term survival of small cell lung cancer. Toraks Dergisi, Cilt: 6 - Sayı: 1, 81–84. https://ajindex.com/articles/368172

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