Journals / Toraks Dergisi / 2004 / Cilt: 5 - Sayı: 2

Spontaneous pneumothorax due to fungal infection after chemotherapy in a case of acute lymphoblastic leukemia with down syndrome

Down sendromlu akut lenfoblastik lösemi olgusunda kemoterapi sonrasi fungal infeksiyona sekonder gelişen spontan pnömotoraks

Pages
116–119
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

After completing the treatment for leukemia, the patient has been under follow-up with remission in the aspect of leukemia and hydropneumothorax.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Spontaneous pneumothorax may occur primarily or secondary due to chronic obstructive pulmonary disease, severe asthma crisis, infections, histiocytosis or malignant conditions.
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Key Findings & Data:Tuberculosis, pneumocystis carinii infection, necrotizing pneumonias and fungal infections are well-documented causes of spontaneous pneumothorax.
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Conclusion & Impact:After completing the treatment for leukemia, the patient has been under follow-up with remission in the aspect of leukemia and hydropneumothorax.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Down sendromu · Lösemi · lenfositik

Abstract

Spontaneous pneumothorax may occur primarily or secondary due to chronic obstructive pulmonary disease, severe asthma crisis, infections, histiocytosis or malignant conditions. Tuberculosis, pneumocystis carinii infection, necrotizing pneumonias and fungal infections are well-documented causes of spontaneous pneumothorax. We here present a case with spontaneous pneumothorax due to fungal infection in the treatment period of acute lymphoblastic leukemia. The patient was diagnosed as acute lymphoblastic leukemia accompanying Down syndrome. The chest Xray in the neutropenic period revealed probable bilateral fungal infiltration and hydropneumothorax at the right side. The patient was treated with closed chest tube drainage and appropriate antibiotherapy. Therapy was resulted with cure in two weeks and drainage was ended. After completing the treatment for leukemia, the patient has been under follow-up with remission in the aspect of leukemia and hydropneumothorax.

Özet

Spontan pnömotoraks primer olabileceği gibi, kronik obstrüktif akciğer hastalığı, ağır astım krizi, infeksiyonlar, histiyositozis ve malign hastalıklara sekonder olarak da gelişebilmektedir. İnfeksiyonlar arasında tüberküloz, pneumocystis carinii pnömonisi, nekrotizan pnömoniler ve fungal infeksiyonlar ön sıralarda gelmektedir. Bu yazıda, akut lenfoblastik lösemi tedavisi esnasında, fungal infeksiyona sekonder spontan pnömotoraks gelişen bir olgu sunulmaktadı r. Hasta 18 yaşında, akut lenfoblastik lösemi tanısı ile hastaneye yatırılmış Down sendromlu bir olgudur. Nötropenik dönemde çekilen akciğer grafisinde bilateral fungal infiltrasyonu düşündüren görünüm ve sağda hidropnömotoraks ile uyumlu görünüm saptanmıştır. Olguya, kapalı su altı drenajı uygulanmış ve antifungal antibiyotik dozu artırılmıştır. Bu tedaviden fayda gören olgu iki hafta içinde düzelmiş ve drenaja son verilmiştir. Lösemi tedavisi de tamamlanan olgu halen izlenmektedir.

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Cite This Article

ŞAHİN, F., GÖRÜMLÜ, G., SAYDAM, G., BÜYÜKKEÇECİ, F. (2004). Spontaneous pneumothorax due to fungal infection after chemotherapy in a case of acute lymphoblastic leukemia with down syndrome. Toraks Dergisi, Cilt: 5 - Sayı: 2, 116–119. https://ajindex.com/articles/368100

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