SavedAdd your journal

Journals / Toraks Dergisi / 2005 / Cilt: 6 - Sayı: 2

Burkholderia cepacia pneumonia mimicking invasive aspergillosis in a hemodialysis patient

Bir hemodiyaliz hastasında invazif aspergillozu taklit eden burkholderia cepacia pnömoni olgusu

Serap DEMİR
Fatma FİDAN
Bumin DEĞİRMENCİ
Yunus ÖZER
Çiğdem GÖKÇE
Pages
175–177
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The resemblance of lesions to aspergilloma and the importance of tissue biopsy result for the diagnosis of aspergilloma were pointed out.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The clinical spectrum of Burkholderia cepacia infection ranges from asymptomatic carrier state to fulminant pneumonia and death.
📊
Key Findings & Data:In this article, a case of B. cepacia pneumonia, which was misdiagnosed as invasive aspergillosis because of the radiological findings, is presented.
💡
Conclusion & Impact:The resemblance of lesions to aspergilloma and the importance of tissue biopsy result for the diagnosis of aspergilloma were pointed out.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Tanı · ayırıcı · Aspergilloz

Abstract

The clinical spectrum of Burkholderia cepacia infection ranges from asymptomatic carrier state to fulminant pneumonia and death. In this article, a case of B. cepacia pneumonia, which was misdiagnosed as invasive aspergillosis because of the radiological findings, is presented. In order to confirm the diagnosis of aspergillosis, culture of bronchoscopic lavage and tissue biopsy were performed and non-specific antibiotic treatment was preferably started. Culture of bronchoalveolar lavage fluid revealed B. cepacia infection and it was treated with ciprofloxacin. With this report, characteristics of the B. cepacia infection, which may be endemic among hemodialysis patients, are reviewed. The resemblance of lesions to aspergilloma and the importance of tissue biopsy result for the diagnosis of aspergilloma were pointed out.

Özet

Burkholderia cepacia infeksiyonunun klinik spektrumu, asemptomatik taşıyıcılıktan fulminan pnömoniye ve ölüme kadar değişir. Bu makalede, bir hemodiyaliz hastamızda tespit edilen, akciğerdeki lezyonların radyolojik görünümü nedeni ile invazif aspergillozla karıştırılan B. cepacia pnömoni olgusu sunulmuştur. Aspergilloz tanısı için hastanın bronkoskopik lavaj kültür sonucu ve doku tanısı beklenmiş ve bu arada nonspesifik tedavi başlanmıştır. Bronkoskopi ile alınan bronkoalveoler lavaj sıvısı kültüründe B. cepacia saptanmış ve siprofloksasinle tedavi edilmiştir. Bu olgu vesilesiyle hemodiyaliz hastalarında endemik olarak da rastlanabilen B. cepacia infeksiyonunun özellikleri gözden geçirilmiş ve lezyonlarının aspergillomayı taklit edebileceği ve aspergilloma tanısı için doku biyopsisi sonucunun önemi vurgulanmıştır.

🔖

Cite This Article

DEMİR, S., FİDAN, F., DEĞİRMENCİ, B., ÖZER, Y., GÖKÇE, Ç. (2005). Burkholderia cepacia pneumonia mimicking invasive aspergillosis in a hemodialysis patient. Toraks Dergisi, Cilt: 6 - Sayı: 2, 175–177. https://ajindex.com/articles/368084

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (14)

  1. Ishizuka T, Oyama T, Sato M et al. Fatal pneumonia caused by Burkholderia cepacia 9 months after resection of aspergilloma. Respirology 2003;8:401-3
  2. Sajjan U, Corey M, Humar A et al. Immunolocalisation of Burkholderia cepacia in the lung of cystic fibrosis patients. J Med Microbiol 2001;50:535-46
  3. Cieri MV, Mayer-Hamblett N, Griffith A, Burns JL. Correlation between an in vitro invasion assay and a murine model of Burkholderia cepacia lung infection. Infect Immun 2002;70:1081-6
  4. Yamagishi Y, Fujita J, Takigawa K et al. Clinical features of Pseudomonas cepacia pneumonia in an epidemic among immunocompromised patients. Chest 1993;103:1706-9
  5. Huang CH, Jang TN, Liu CY et al. Characteristics of patients with Burkholderia cepacia bacteremia. J Microbiol Immunol Infect 2001; 34:215-9
  6. Frangolias DD, Mahenthiralingam E, Rae S et al. Burkholderia cepacia in cystic fibrosis. Variable disease course. Am J Respir Crit Care Med 1999;160:1572-7
  7. Muhdi K, Edenborough FP, Gumery L et al. Outcome for patients colonized with Burkholderia cepacia in a Birmingham adult cystic fibrosis clinic and the end of an epidemic. Thorax 1996;51:374-7
  8. Chernish RN, Aaron SD. Approach to resistant gram-negative bacterial pulmonary infections in patients with cystic fibrosis. Curr Opin Pulm Med 2003;9:509-15
  9. Wilson DL, Owens RC Jr, Zuckerman JB. Successful meropenem desensitization in a patient with cystic fibrosis. Ann Pharmacother 2003; 37:1424-8
  10. Bonacorsi S, Fitoussi F, Lhopital S, Bingen E. Comparative in vitro activities of meropenem, imipenem, temocillin, piperacillin and ceftazidime in combination with tobramycin, rifampin or ciprofloxacin against Burkholderia cepacia isolates from patients with cystic fibrosis. Antimicrob Agents Chemother 1999;43:213-7
  11. Saiman L, Chen Y, Gabriel PS, Knirsch C. Synergistic activities of macrolide antibiotics against Pseudomonas aeruginosa, Burkholderia cepacia, Stenotrophomonas maltophilia and Alcaligenes xylosoxidans isolated from patients with cystic fibrosis. Antimicrob Agents Chemother 2002; 46:1105-7
  12. Conway SP, Brownlee KG, Denton M, Peckham DG. Antibiotic treatment of multidrug-resistant organisms in cystic fibrosis. Am J Respir Med 2003;2:321-32
  13. Belchis DA, Simpson E, Colby T. Histopathologic features of Burkholderia cepacia pneumonia in patients without cystic fibrosis. Mod Pathol 2000;13:369-72
  14. Descamps-Latscha B. The immune system in end-stage renal disease. Curr Opin Nephrol Hypertens