Journals / Toraks Dergisi / 2006 / Cilt: 7 - Sayı: 2

The relationship between endoscopic appearance and biopsy techniques productivity in subjects with lung cancer diagnosed by flexible fiberoptic broncoscopy

Fleksibl fiberoptik bronkoskopi ile tanı konulan akciğer kanseri olgularında endoskopik görünüm ile biyopsi tekniklerinin tanı değeri arasındaki ilişki

Pages
109–114
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

In the light of these findings and the literature, we concluded that; 1-Each biopsy technique has advantages and disadvantages peculiar to itself; thus, as it is possible, different biopsy techniques should be used together. 2-Bronchial aspiration is easy, cheap and noninvasive method; thus, it should be undoubtedly added to combination. 3-High diagnostic productivity can be obtained with forceps biopsy plus brush biopsy in subjects with direct tumoral findings such as vegetan tumor or tumoral infiltration; however, forceps biopsy plus TBFNA offers high diagnostic productivity in subjects with indirect tumoral findings.

📌 3 Key Takeaways

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Objective & Hypothesis:The aim of the present study was to investigate the relationship between endobronchial appearance and the productivity of broncoscopic techniques in subjects with lung cancer diagnosed by broncoscopic methods.
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Key Findings & Data:Three hundred and thirty two subjects with lung cancer diagnosed between 2000-2003 were included in the present study.
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Conclusion & Impact:In the light of these findings and the literature, we concluded that; 1-Each biopsy technique has advantages and disadvantages peculiar to itself; thus, as it is possible, different biopsy techniques should be used together. 2-Bronchial aspiration is easy, cheap and noninvasive method; thus, it should be undoubtedly added to combination. 3-High diagnostic productivity can be obtained with forceps biopsy plus brush biopsy in subjects with direct tumoral findings such as vegetan tumor or tumoral infiltration; however, forceps biopsy plus TBFNA offers high diagnostic productivity in subjects with indirect tumoral findings.
🔬Design:Research Article
📍Scope:2000-2003 Verileri
⚙️Variables:Akciğer neoplazmları · Bronkoskopi · Biyopsi

Abstract

The aim of the present study was to investigate the relationship between endobronchial appearance and the productivity of broncoscopic techniques in subjects with lung cancer diagnosed by broncoscopic methods. Three hundred and thirty two subjects with lung cancer diagnosed between 2000-2003 were included in the present study. Forceps biopsy alone was the most valuable diagnostic method with 90.3% diagnostic success rate in compared with other methods applied alone in all cases. Forceps biopsy plus transbronchial fine needle aspiration (TBFNA) offered 97.6% diagnostic success rate. In direct tumoral findings such as tumoral infiltration and vegetan tumor, forceps biopsy offered 93.2% and 97.7% positive result, respectively. The positive diagnostic rate was 80% in indirect tumoral group. The results was statistically significant (p<0.05). No relationship was observed between broncoscopic appearance and TBFNA or brush biopsy or bronchial aspiration (p= 0.97, p= 0.79, p= 0.12, respectively). Forceps biopsy plus bronchial aspiration offered up to 97.6% diagnostic success rate in subjects with vegetan tumoral finding. In subjects with tumoral infiltration finding, diagnostic success rate was 97.1% with the usage of combination of forceps biopsy and transbronchial fine needle aspiration techniques. With the addition of bronchial aspiration to combination of forceps biopsy and transbronchial fine needle aspiration, diagnostic success rate reached up to 98.4%. In subjects with indirect tumoral findinds, forceps biopsy plus transbronchial fine needle aspiration offered up to 96.7% diagnostic success rate. In the light of these findings and the literature, we concluded that; 1-Each biopsy technique has advantages and disadvantages peculiar to itself; thus, as it is possible, different biopsy techniques should be used together. 2-Bronchial aspiration is easy, cheap and noninvasive method; thus, it should be undoubtedly added to combination. 3-High diagnostic productivity can be obtained with forceps biopsy plus brush biopsy in subjects with direct tumoral findings such as vegetan tumor or tumoral infiltration; however, forceps biopsy plus TBFNA offers high diagnostic productivity in subjects with indirect tumoral findings.

Özet

Bu çalışmada tanısı bronkoskopik yöntemler ile konan akciğer kanseri olgularında endobronşiyal görünüm ile bronkoskopik biyopsi tekniklerinin verimliliği arasındaki ilişki araştırıldı. Çalışmaya 2000-2003 yılları arasında tanı alan 332 olgu alındı. Tüm olgular değerlendirildiğinde en yüksek tanı değeri forseps biyopsi ile elde edildi (%90.3). Forseps biyopsi + Transbronşiyal iğne aspirasyon biyopsisi (TBİAB) ile %97.6 oranında tanı elde edildi. Direkt tümör bulguları olan tümöral infiltrasyon ve vejetan tümörde forseps biyopsi ile %93.2 ve %97 pozitif sonuç elde edilirken, indirekt tümör grubunda tanı oranı %80.0 olarak bulundu. Sonuçları istatistiksel olarak anlamlıydı (p<0.05). TBİAB, fırça biyopsi, bronş aspirasyonunun tanısal değerinin bronkoskopik görünüm ile bir ilişkisi yoktu (sırasıyla p= 0.97, p= 0.79, p= 0.12). Vejetan tümör bulgusu olanlarda forseps biyopsi + bronş aspirasyonu kombinasyonu ile %97.6 tanıya ulaşıldı. Tümöral infiltrasyonlu olgularda forseps biyopsi+ TBİAB ile %97.1 bunlara bronş aspirasyonu eklendiğinde % 98.4 tanı elde edildi. İndirekt tümör bulgusu veren olgularda forseps biyopsiye TBİAB eklendiğinde %96.7 tanıya ulaşıldı. Çalışmamızdan elde edilen verilere ve literatür bilgilerine bakarak aşağıdaki sonuçlara vardık. 1. Her biyopsi tekniğinin kendine has avantaj ve dezavantajları olduğu için mümkün olduğunca farklı teknik bir arada kullanılmalıdır. 2. Bronş aspirasyonu kolay, ucuz ve noninvaziv bir teknik olduğu için kombinasyona mutlaka eklenmelidir. 3. Vejetan tümör yada tümöral infiltrasyon gibi direkt tümör bulgusu olan olgularda forseps + TBİAB ve bunlara ek olarak bronş aspirasyonu; indirekt tümör bulgusu olan olgularda forseps + TBİAB ile yüksek tanı verimliliği elde edilebilmektedir.

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Cite This Article

USLU, Ö., TUKSAVUL, F., GÜNAÇTI, E., ERBAYCU, A. E., VATANSEVER, T., GÜÇLÜ, S. Z. (2006). The relationship between endoscopic appearance and biopsy techniques productivity in subjects with lung cancer diagnosed by flexible fiberoptic broncoscopy. Toraks Dergisi, Cilt: 7 - Sayı: 2, 109–114. https://ajindex.com/articles/368062

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