Journals / Toraks Dergisi / 2007 / Cilt: 8 - Sayı: 4

Malignant melanoma and endobronchial metastasis (two cases)

Malign melanom ve endobronşial metastaz (iki olgu nedeniyle)

Pages
241–243
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Chemotherapy was started, however, since the patient failed to attend for control visits, he could only be followed up for 12 months after chemotherapy.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Malignant melanoma, which is formed by malignant transformation of melanocytes, metastasizes to pulmonary tissue via tumor embolies reaching the pulmonary arteries.
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Key Findings & Data:The first case was a 31-year-old man with malignant melanoma,and brain, bone, and stomach metastases.
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Conclusion & Impact:Chemotherapy was started, however, since the patient failed to attend for control visits, he could only be followed up for 12 months after chemotherapy.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Erkek · Öksürük · Bronkoskopi

Abstract

Malignant melanoma, which is formed by malignant transformation of melanocytes, metastasizes to pulmonary tissue via tumor embolies reaching the pulmonary arteries. Since only a limited number of cases have been reported in the literature, we present two cases of malignant melanoma with endobronchial lung metastases. The first case was a 31-year-old man with malignant melanoma,and brain, bone, and stomach metastases. His lung x-ray revealed nodular opacities, and a biopsy taken from the bronchial mucosal lesion during bronchoscopy was diagnosed as malignant melanoma. Despite chemotherapy, radiotherapy and immunotherapy, he died 6 months after the diagnosis of endobronchial metastasis. The second case was a 70-year-old man with hemoptysis who was previously diagnosed as malignant melanoma. His lung x-ray revealed a nodular opacity and a biopsy taken from the bronchial mucosal lesion during bronchoscopy was diagnosed as malignant melanoma. Chemotherapy was started, however, since the patient failed to attend for control visits, he could only be followed up for 12 months after chemotherapy.

Özet

Melonositlerin malign transformasyonu sonucu gelişen malign melanom, pulmoner metastazlarını esas olarak pulmoner arterlere ulaşan tümör embolileri ile yapmaktadır. Akciğere endobronşial yayılım yapmış malign melanom olguları literatürde oldukça sınırlı sayıdadır. Bu nedenle, kliniğimizde takip ettiğimiz endobronşial yayılım yapmış iki malign melanom olgusunu sunmaktayız. Birinci olgu 31 yaşında, beyin, kemik ve mide metastazları bulunan malign melanom tanılı erkek hastadır. Akciğer PA grafisinde nodüler opasiteler mevcuttur ve yapılan bronkoskopisinde alınan bronş mukoza biopsi materyalinin sonucu malign melanom olarak gelmiştir. Uygulanan kemoterapi, radyoterapi ve immünoterapiye rağmen hasta endobronşial metastazın saptanmasından yaklaşık 6 ay sonra eksitus olmuştur. İkinci olgu, 70 yaşında önceden malign melanom tansı bulunan erkek hastadır. Hemoptizi nedeni ile yapılan incelemesinde, PA akciğer grafisinde nodüler opasite mevcuttur ve bronkoskopisinde alınan bronş mukoza biopsi materyalini sonucu malign melanom olarak gelmiştir. Hastaya kemoterapi başlanmıştır. Hasta kontrollere gelmediği için kemoterapi sonrası ancak 12 ay izlenebilmiştir.

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Cite This Article

KÖSEOĞLU, N., AKKOÇLU, A., KILINÇ, O., YILMAZ, E., SEVİNÇ, C. (2007). Malignant melanoma and endobronchial metastasis (two cases). Toraks Dergisi, Cilt: 8 - Sayı: 4, 241–243. https://ajindex.com/articles/368056

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