Journals / Toraks Dergisi / 2002 / Cilt: 3 - Sayı: 3

Effect of resting expiratory flow rates and arterial blood gas values on exercise performance in COPD

KOAH'lı istirahat koşullarında ekspiratuar akım hızları ve arter kan gazı değerlerinin egzersiz performansına etkisi

Pages
242–247
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

As a result of this study, we concluded that exercise stress testing (treadmill ergometer) may have important role, to estimate severity of disease, to follow patients and to organize exercise training especially in moderate and severe patients with COPD.

📌 3 Key Takeaways

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Objective & Hypothesis:The aim of this study was to examine the relationship between rest spirometry values and treadmill exercise testing parameters (TETP) in patients with COPD.
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Key Findings & Data:We studied 45 patients with COPD (9 female and 36 male, age 61±11years) and as a control group, 21 healthy subjects (5 female and 16 male, age 60±10 years).
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Conclusion & Impact:As a result of this study, we concluded that exercise stress testing (treadmill ergometer) may have important role, to estimate severity of disease, to follow patients and to organize exercise training especially in moderate and severe patients with COPD.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Akciğer hastalıkları · tıkanma · Egzersiz testi

Abstract

The aim of this study was to examine the relationship between rest spirometry values and treadmill exercise testing parameters (TETP) in patients with COPD. We studied 45 patients with COPD (9 female and 36 male, age 61±11years) and as a control group, 21 healthy subjects (5 female and 16 male, age 60±10 years). Patients with COPD (group I) divided into three subgroup [mild (group II): FEV1 %60-79, moderate (group III): FEV1 %40-59, severe (group IV): FEV1 < 40%] according to FEV1 values. Arterial blood samples were taken for blood gas and pH before spirometry. Resting pulmonary function parameters were obtained from subjects by spirometer. Symptom-limited maximal exercise testing was completed on treadmill ergometer. High correlation between FEV 1 and TETP [total treadmill time (TTT), total MET values (TMETs), maximal mVO2 (mVO2), maximal heart rate (mHR)] were found in the patients with COPD (respectively: p<0. 01, p<0. 02, p<0.01, p<0.01). Additionally, the lower corelation between PaO2 and TETP (mVO2, TTT, TMETs, mHR) were found (p<0.03, p<0.04, p<0.045, p<0.04, respectively). This study shows significant correllations between resting expiratory flow parameters (FEV1 values), arterial blood gas values and TETP in patients with COPD. As a result of this study, we concluded that exercise stress testing (treadmill ergometer) may have important role, to estimate severity of disease, to follow patients and to organize exercise training especially in moderate and severe patients with COPD.

Özet

Bu çalışmada KOAH'lılarda istirahat koşullarında ekspiratuar akım hızları ve kan gazı değerlerinin yürüme bandında efor testi parametreleri (treadmill exercise testing parametres: TETP) ile ilişkisi ve bunun hastalığın şiddetini öngörmedeki değeri araştırılmıştır. Bu çalışmaya 45 KOAH'lı hasta (kadın/erkek: 9/36, yaş ortalaması: 61±11yıl) ve 21 sağlıklı birey (kadın/erkek: 4/17, yaş ortalaması: 60±10 yıl) alındı. Tüm KOAH'lı hastalar (I. grup, FEV1 %51.3±7.2) FEV1 değerlerine göre 3 altgruba (II. grup/hafif KOAH, FEV1 %60-79, III. grup/orta düzeyde KOAH, FEV1 %40-59, IV. grup/ileri derecede KOAH, FEV1 %80 idi. Tüm gruplara istirahat koşullarında spirometri ile SFT ve sonrasında semptomla sınırlı maksimum efor testi uygulandı. Toplam koşu süresi (TKS), toplam metabolik eşdeğerleri (TMET), maksimum VO2 ( mVO2) düzeyleri ve maksimum kalp hızı (mKH), III. grup (mV02: 17.6±4.9; p<0.0001, TKS: 3.8±1.1; p<0.0001, TMET: 4.8±1.3, p<0.001, mKH: 127.9±17.3 p<0.01) ve IV. grupta (mVO2: 15.2±5.3, p<0.0001, TKS: 3.3±1.2, p<0.0001, TMET: 3.9±1.5, p<0.0001, mKH: 114.9±15.6, p<0.001) kontrollere (mVO2: 27.3±5.9, TKS: 7.1±1.3, TMET: 8.3±2.2, mKH: 137.3±13.4) göre anlamlı farklılık göstermekteydi. Ek olarak IV. grupta ventriküler erken atım sayısı (VEAS) kontrol grubuna göre anlamlı olarak artmıştı (2.9±1.4'e 1.7±1.1, p<0.01). Hafif KOAH grubunun tüm değerleri kontrol grubuna benzerdi. FEV1 ile TETP arasında III. grupta (mVO2: r=0.35/p<0.005, TKS: r=0.31/p<0.01, TMET: r=0.29/p<0.01) ve IV. grupta (mVO2: r=0.49/p<0.001, TKS: r=0.45/p<0.005, TMET: r=0.31/p<0.01, mKH: r=0.29/p<0.01, VEAS: r=0.27/p<0.05) anlamlı korelasyonlar saptandı. Ayrıca IV. grupta PaO22 değerleri ile TETP arasında da benzer bir ilişki (mVO2: r=0.43/p<0.005, TKS: r=0.35/p<0.01, TMET: r=0.32/p<0.02, mKH: r=0.31/p<0.03, VEAS: r=-0.29/p<0.05) bulundu. Bu çalışmada orta-ileri derecede KOAH'lılarda istirahat ekspiratuar akım hızları ve PaO2 değerleri ile efor testi parametreleri arasında yakın bir ilişki olduğu ve bu ilişkinin hastalığın ciddiyetini öngörmede önemli bir rolü olabileceği sonucuna vardık.

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Cite This Article

YAZICI, M., ARBAK, P., BALBAY, Ö., MADEN, E., ERBAŞ, M., ERBİLEN, E., ALBAYRAK, S., AKDEMİR, R., UYAN, C. (2002). Effect of resting expiratory flow rates and arterial blood gas values on exercise performance in COPD. Toraks Dergisi, Cilt: 3 - Sayı: 3, 242–247. https://ajindex.com/articles/368014

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