Journals / Toraks Dergisi / 2002 / Cilt: 3 - Sayı: 3

Nutritional status and lung function in patients with COPD

KOAH'lı hastalarda beslenme durumu ve solunum fonksiyonları

Pages
236–241
DOI
—
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⚡ TL;DR(Too Long; Didn't Read)

We determined that respiratory functions were closely related to nutritional parameters in COPD cases.

📌 3 Key Takeaways

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Objective & Hypothesis:To investigate the relationship between nutritional status and lung function, 75 hospitalized COPD patients were evaluated.
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Key Findings & Data:Anthropometric measurements (percent ideal body weight (PIW), body mass index (BMI), triceps skin fold thickness (TSF), arm muscle circumference (AMC)), respiratory function parameters (FEV1, FVC, VC, FEV1/FVC, pH, pCO2, pO2), biochemical parameters (serum prealbumin, transferrin, albumin) and immunological parameter (total lymphocyte count (TLC) were worked out and nutritional index (NI) was calculated.
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Conclusion & Impact:We determined that respiratory functions were closely related to nutritional parameters in COPD cases.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Beslenme durumu · Akciğer hastalıkları · tıkanma

Abstract

To investigate the relationship between nutritional status and lung function, 75 hospitalized COPD patients were evaluated. Anthropometric measurements (percent ideal body weight (PIW), body mass index (BMI), triceps skin fold thickness (TSF), arm muscle circumference (AMC)), respiratory function parameters (FEV1, FVC, VC, FEV1/FVC, pH, pCO2, pO2), biochemical parameters (serum prealbumin, transferrin, albumin) and immunological parameter (total lymphocyte count (TLC) were worked out and nutritional index (NI) was calculated. According to NI, we determined malnutrition in 68% of COPD patients. PIW, BMI, prealbumin levels were found to be significantly different for cases with emphysema and chronic bronchtis (Mann-Whitney U test, p<0.01). According to their FEV1 levels, the cases were classified as mild, moderate and severe COPD (stageI-II-III COPD), using ATS classification. A significant difference was found in albumin, transferrin, prealbumin, TLC, TSF, and AMC levels between mild and severe COPD groups (between stage 1-3 COPD) (p<0.01). There was no difference observed in BMI, PIW levels between the different stages of COPD. According to NI levels, PO2, FEV1 were observed to be significantly higher in cases with NI<0.5 (p<0.05). We determined that respiratory functions were closely related to nutritional parameters in COPD cases.

Özet

Beslenme durumu ve solunum fonksiyonu arasındaki ilişkiyi araştırmak amacıyla hastanede yatan 75 KOAH'lı olgu değerlendirildi. Antropometrik ölçümler (ideal vücut kilosu yüzdesi (PİW), vücut kitle indeksi (VKİ), triceps cilt kalınlığı (TCK), kol çevresi ölçümleri (KÇ)), solunum fonksiyon parametreleri (FEV1, FVC, VC, FEV1/FVC, pH, pCO2, pO2), beslenme parametreleri (serum prealbümin, transferrin, albümin), immünolojik parametre (total lenfosit sayısı (TLS)) incelendi ve beslenme indeksi (nutritional index: NI) hesaplandı. KOAH'lı olgularımızın %68'inde NI'ye göre malnütrisyon saptandı. Amfizem ve kronik bronşit olarak gruplanan olgular arasında, PIW, VKİ, prealbümin düzeyleri anlamlı olarak farklı bulundu (Mann-Whitney U test, p<0.05). Olgular FEV1 düzeylerine göre ATS sınıflamasıyla hafif, orta, ağır KOAH (evre 1-2-3) olarak evrelendi. Hafif ve ağır KOAH (evre 1-3) grupları arasında albümin, transferrin, prealbümin, TLS, TCK ve KÇ düzeylerinde anlamlı farklılık gözlendi (p<0.01). KOAH'ın evreleriyle VKİ, PİW düzeylerinde farklılık bulunmadı. NI <0.5 olan olgularda p02, FEV1 anlamlı olarak daha yüksek saptandı (p<0.05). KOAH'lı olgularda solunum fonksiyonlarının beslenme parametreleriyle yakın ilişkili olduğunu saptadık.

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Cite This Article

BALIOĞLU, M., KÖMÜRCÜOĞLU, B., BİÇMEN, C., ÇELİKTEN, E., AKTOĞU, S. (2002). Nutritional status and lung function in patients with COPD. Toraks Dergisi, Cilt: 3 - Sayı: 3, 236–241. https://ajindex.com/articles/368005

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