Journals / Toraks Dergisi / 2002 / Cilt: 3 - Sayı: 2

The diagnostic value of gastric and bronchial lavage in suspected cases of pulmonary tuberculosis

Akciğer tüberkülozu düşünülen hastalarda açlık mide suyu ve bronş lavajının tanısal değeri

Pages
151–155
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Therefore we suggest that in cases that are unable to expectorate sputum, obtaining GL and in cases with negative sputum smear, performing BL would be helpful.

📌 3 Key Takeaways

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Objective & Hypothesis:We aimed to assess whether acid-fast bacilli (AFB) determination in gastric lavage (GL) and bronchial lavage (BL) contributes to evaluation of cases radiologically suggestive of pulmonary tuberculosis but with negative AFB in sputum or unable to expectorate sputum.
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Key Findings & Data:Although 168 cases were enrolled into the study, at the end, 22 cases were excluded because they were evaluated as having inactive tuberculosis or a disease other than tuberculosis.
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Conclusion & Impact:Therefore we suggest that in cases that are unable to expectorate sputum, obtaining GL and in cases with negative sputum smear, performing BL would be helpful.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Bronkoalveolar lavaj sıvısı · Kültür ortamı · Tüberküloz

Abstract

We aimed to assess whether acid-fast bacilli (AFB) determination in gastric lavage (GL) and bronchial lavage (BL) contributes to evaluation of cases radiologically suggestive of pulmonary tuberculosis but with negative AFB in sputum or unable to expectorate sputum. Although 168 cases were enrolled into the study, at the end, 22 cases were excluded because they were evaluated as having inactive tuberculosis or a disease other than tuberculosis. The remaining 146 cases were evaluated in 3 groups. Group A consisted of 49 patients that could not expectorate sputum and in these patients only GL was obtained. In group B, AFB was negative in sputum and only BL was performed in these 58 patients. In group C, there were 39 patients that were unable to expectorate sputum and negative for AFB in GL, additionally BL was performed in these patients. Smear positivity was 30/49 (61.2%) and culture positivity was 15/49 (30.6%) in group A patients. In-group B, smear positivity was 30/58 (51.7%) and culture positivity was 47/58 (81.0%). In-group C, BL smear positivity and culture positivity were 6/39 (15.4%) and 21/39 (53.8%) respectively and GL culture positivity was 13/39 (33.3%). Thirteen cases in whom AFB could not be detected microbiologically but who were strongly suggestive of tuerculosis radiologically, were regarded as tuberculosis according to 'from treatment to diagnosis' criteria. Detection of AFB culture positivity in diagnosis of tuberculosis is important in terms of early initiation of treatment and detection of resistant bacilli. Therefore we suggest that in cases that are unable to expectorate sputum, obtaining GL and in cases with negative sputum smear, performing BL would be helpful.

Özet

Bu çalışmada, radyolojik olarak akciğer tüberkülozu düşünülen, ancak balgam yaymada aside dirençli basil (ARB) negatif olan ya da balgam çıkaramayan hastalarda ARB incelemesi için alınan açlık mide suyu (AMS) ve bronş lavajının (BL) tanısal değerini incelemeyi amaçladık. Çalışmaya 168 olgu alındı. Çalışma sonunda 22 olgu, inaktif tüberküloz veya tüberküloz dışı hastalık olarak değerlendirildiğinden çalışma dışı tutuldu. Kalan 146 olgu 3 grupta incelendi. Grup A balgam çıkaramayan ve sadece AMS alınan 49 olgudan oluşuyordu. Grup B balgam yaymasında ARB negatif olan ve sadece BL uygulanan 58 olguydu. Grup C ise balgam çıkaramayan ve AMS yayma negatif olan 39 olguydu. Bu olgulara ayrıca BL uygulandı. Grup A olgularında yayma pozitifliği 30/49 (%61.2), kültür pozitifliği 15/49 (%30.6) idi. Grup B olgularında yayma pozitifliği 30/58 (%51.7), kültür pozitifliği 47/58 (%81.0) idi. Grup C'de BL yayma pozitifliği 6/39 (%15.4), BL kültür pozitiflği 21/39 (%53.8) olup AMS kültür pozitifliği 13/39 (%33.3) idi. Mikrobiyolojik olarak ARB saptanamayan, ancak klinik ve radyolojik olarak tüberküloz şüphesi kuvvetli olan 13 olgu 'tedaviden tanıya' ölçütü ile tüberküloz kabul edildi. Tüberküloz tanısında ARB kültür pozitifliğinin saptanması gerek tedaviye erken başlanması gerekse dirençli basillerin belirlenmesi açısından önemlidir. Bu nedenle balgam çıkaramayan olgularda AMS, balgam yaymasının ARB açısından negatif olduğu olgularda da BL alınmasının yararlı olacağı düşüncesindeyiz.

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Cite This Article

OKUTAN, O., KARTALOĞLU, Z., KILIÇ, E., BOZKANAT, E., İLVAN, A. (2002). The diagnostic value of gastric and bronchial lavage in suspected cases of pulmonary tuberculosis. Toraks Dergisi, Cilt: 3 - Sayı: 2, 151–155. https://ajindex.com/articles/368002

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