Journals / Toraks Dergisi / 2008 / Cilt: 9 - Sayı: 1

Serum antioxidant vitamins (A, E, C), selenium and melondialdehyde levels in workers exposed to aerosol

Aerosole maruz kalan işçilerde, serum antioksidan vitaminler (A, E, C), selenyum ve malondialdehit düzeyleri

Pages
13–16
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

To determine whether the observed results were related to endogen antioxidant deficiency or vitamin deficiency or Se levels deficiency, or whether another unknown agent is involved requires further investigation.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:We investigated serum antioxidant vitamins (A, E and C), selenium (Se) and malondialdehyde (MDA) levels in subjects who were exposed to aerosol (dye products) via inhalation, as compared to unexposed control subjects.
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Key Findings & Data:Twenty paint workers and 22 controls participated for this study.
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Conclusion & Impact:To determine whether the observed results were related to endogen antioxidant deficiency or vitamin deficiency or Se levels deficiency, or whether another unknown agent is involved requires further investigation.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Vitamin E · Vitaminler · Mesleki maruziyet

Abstract

We investigated serum antioxidant vitamins (A, E and C), selenium (Se) and malondialdehyde (MDA) levels in subjects who were exposed to aerosol (dye products) via inhalation, as compared to unexposed control subjects. Twenty paint workers and 22 controls participated for this study. The serum vitamins (A, E, C) MDA and Se levels in both groups were measured using HPLC. The levels of vitamin A, E and selenium levels were significantly decreased in workers (p<0.05), while serum MDA levels were significantly increased (p<0.005), and the levels of vitamin C were almost the same in dye paint workers as in the control subjects (p>0.05). Free radical activity (oxidative stress) levels were increased whereas non-enzymatic parameters were decreased in painters exposed to aerosol inhalation compared to con- trols. To determine whether the observed results were related to endogen antioxidant deficiency or vitamin deficiency or Se levels deficiency, or whether another unknown agent is involved requires further investigation.

Özet

Boyacılık mesleğinde çalışmakta olan ve çalıştıkları iş ortamında kullanılan aerosol şeklindeki boya ürünlerine inhalasyon yoluyla maruz kalan kişilerin serumlarında antioksidan vitaminler (A, E, C), malondialdehit (MDA) ve selenyum (Se) düzeylerinin, normal kontrol değerlerine göre değişimleri araştırıldı. Boyacılık mesleğinde çalışan 20 kişi ve kontrol grubu olarak saptanan sağlıklı 22 kişinin serum vitamin A, E, C, MDA ve Se düzeyleri HPLC ile belirlendi. Kontrol grubuna göre, boyacıların vitamin A, E ve Se düzeyleri düşük bulundu (p 0.05). Sonuç olarak, boyacılarda serbest radikal aktivitenin (oksidatif stresin) anlamlı düzeyde arttığı; buna karşın non-enzimatik antioksidan sistemi yansıtan parametrelerin serum düzeylerinde düşüklük (vitamin A ve E ve Se) saptanmıştır. Bu sonucun, endojen antioksidan savunmanın serbest radikal artışını karşılayamaması sonucu gelişen tüketim artışına mı, yoksa bir başka etkenin yol açtığı antioksidan vitamin ve Se yetersizliğine mi bağlı olduğunun belirlenmesi bu çalışmanın daha ileri bir aşaması olmalıdır.

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Cite This Article

KARATAŞ, F., TUĞ, T., KONAR, V. (2008). Serum antioxidant vitamins (A, E, C), selenium and melondialdehyde levels in workers exposed to aerosol. Toraks Dergisi, Cilt: 9 - Sayı: 1, 13–16. https://ajindex.com/articles/367905

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