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Journals / The Anatolian Journal of Cardiology / 2019 / Cilt: 21 - Sayı: 4

Higher ultrafiltration rate is associated with right ventricular mechanical dispersion

Serkan ÜNLÜ
Efstathios D PAGOURELİAS
BURAK SEZENÖZ
ASİFE ŞAHİNARSLAN
Mecit Orhan ULUDAĞ
Gökhan GÖKALP
Selim Turgay ARINSOY
Atiye ÇENGEL
Pages
206–213
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Ultrafiltration rates and volumes should be kept as low aspossible to achieve hemodynamic stability and tolerability. (Anatol J Cardiol 2019; 21: 206-13)

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Ultrafiltration rate is one of the major determinants of adverse outcomes in patients undergoing hemodialysis (HD) therapy.
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Key Findings & Data:The aim of the present study was to evaluate the impact of high ultrafiltration rate (HUR) on RVmechanical dyssynchrony.Methods: Echocardiographic images focused on the RV and left ventricle (LV) were obtained from 60 patients (49.2±17.3 years, 22 female) beforeand after HD.
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Conclusion & Impact:Ultrafiltration rates and volumes should be kept as low aspossible to achieve hemodynamic stability and tolerability. (Anatol J Cardiol 2019; 21: 206-13)
🔬Design:Research Article
📍Scope:2019 Verileri
⚙️Variables:Domain Parameters

Özet

Objective: Ultrafiltration rate is one of the major determinants of adverse outcomes in patients undergoing hemodialysis (HD) therapy. Previousstudies have focused on the impact of HD on right ventricular (RV) peak strain values. However, the influence of HD on the temporal characteristics of deformation has not been reported yet. The aim of the present study was to evaluate the impact of high ultrafiltration rate (HUR) on RVmechanical dyssynchrony.Methods: Echocardiographic images focused on the RV and left ventricle (LV) were obtained from 60 patients (49.2±17.3 years, 22 female) beforeand after HD. Patients were divided into two groups according to ultrafiltration rate. Changes in echocardiographic parameters with HD wereexamined. Two-dimensional speckle-tracking strain analysis was used to assess deformation. Mechanical dispersion was measured as thestandard deviation of time to peak longitudinal strain of six segments for RV and 18 segments for LV.Results: The average ultrafiltrated volume and ultrafiltration rate were 3000.1±1007.9 mL and 11.4±2.9 mL/kg/h, respectively. Global longitudinalstrain (GLS) of the RV and LV decreased after HD in both groups. A significant difference was observed in RV mechanical dispersion with HDfor patients in the high ultrafiltration group. A mild statistically insignificant increase in LV mechanical dispersion was also observed after HD.Conclusion: HUR has a substantial impact on LV and RV GLS and RV dyssynchrony. Ultrafiltration rates and volumes should be kept as low aspossible to achieve hemodynamic stability and tolerability. (Anatol J Cardiol 2019; 21: 206-13)

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Cite This Article

ÜNLÜ, S., PAGOURELİAS, E. D., SEZENÖZ, B., ŞAHİNARSLAN, A., ULUDAĞ, M. O., GÖKALP, G., ARINSOY, S. T., ÇENGEL, A. (2019). Higher ultrafiltration rate is associated with right ventricular mechanical dispersion. The Anatolian Journal of Cardiology, Cilt: 21 - Sayı: 4, 206–213. https://ajindex.com/articles/366788

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