Journals / The Anatolian Journal of Cardiology / 2015 / Cilt: 15 - Sayı: 6

Aşikar yapısal kalp hastalığı olmayan hastalarda fragmente QRS prematüre ventriküler atım sıklığıyla ilişkilidir

Fragmented QRS is associated with frequency of premature ventricular contractions in patients without overt cardiac disease

Pages
456–462
DOI
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⚡ TL;DR(Too Long; Didn't Read)

In the multinomial regression analysis, only age (odds ratio: 4.24, 95% confidence interval 2.08-8.64, p=0.001) and fQRS (odds ratio: 2.11, 95% confidence interval 1.00-4.45, p=0.05) were predictors of frequent PVCs.Conclusion: This study demonstrated that the presence of fQRS is associated with frequent PVCs in patients without overt structural heart disease

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Objective & Hypothesis:Objective: In this study, we aimed to demonstrate whether the presence of fragmented QRS (fQRS) is associated with the frequency of premature ventricular contractions (PVCs).Methods: We retrospectively analyzed 282 cases by 24-hour Holter monitorings (HMs) between August 2012 and February 2013.
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Key Findings & Data:Firstly, the patients were divided into 2 groups with respect to presence of fQRS and then divided into 3 groups with respect to frequency of PVCs as Group 1: seldom PVC (<120 PVCs/day), Group 2: moderate-frequency PVC (120-720 PVCs/day), and Group 3: frequent PVC (>720 PVCs/day).
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Conclusion & Impact:In the multinomial regression analysis, only age (odds ratio: 4.24, 95% confidence interval 2.08-8.64, p=0.001) and fQRS (odds ratio: 2.11, 95% confidence interval 1.00-4.45, p=0.05) were predictors of frequent PVCs.Conclusion: This study demonstrated that the presence of fQRS is associated with frequent PVCs in patients without overt structural heart disease
🔬Design:Research Article
📍Scope:2012 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: In this study, we aimed to demonstrate whether the presence of fragmented QRS (fQRS) is associated with the frequency of premature ventricular contractions (PVCs).Methods: We retrospectively analyzed 282 cases by 24-hour Holter monitorings (HMs) between August 2012 and February 2013. Firstly, the patients were divided into 2 groups with respect to presence of fQRS and then divided into 3 groups with respect to frequency of PVCs as Group 1: seldom PVC (<120 PVCs/day), Group 2: moderate-frequency PVC (120-720 PVCs/day), and Group 3: frequent PVC (>720 PVCs/day). We investigated the predictors of frequent PVCs by using multinomial logistic regression analysis.Results: Ninety-eight patients had fQRS. There was no difference between the 2 groups with respect to body mass index, gender, hypertension, and diabetes mellitus. Patients with fQRS were older (54.9±15.6 vs. 47.0±16.3, p<0.001) and had more family history of coronary artery disease (25% vs. 13%, p=0.012). Patients with fQRS was more likely to be on aspirin therapy (28.6% vs. 10.4%, p<0.001) and have a larger left atrium diameter (33.5±5.7 vs. 30.4±5.8, p=0.001). Presence of fQRS was significantly associated with the frequency of PVCs (for frequent PVC 27.7% vs. 7.6%, p<0.001; for moderate-frequency PVC 18.4% vs. 11.4%, p=0.012); 26.2% of Group 1 (n=202) had fQRS, 46.2% of Group 2 (n=39) had fQRS, and 65.9% of Group 3 (n=41) had fQRS. In the multinomial regression analysis, only age (odds ratio: 4.24, 95% confidence interval 2.08-8.64, p=0.001) and fQRS (odds ratio: 2.11, 95% confidence interval 1.00-4.45, p=0.05) were predictors of frequent PVCs.Conclusion: This study demonstrated that the presence of fQRS is associated with frequent PVCs in patients without overt structural heart disease

Özet

Amaç: Bu çalışmada, fragmente QRS (fQRS) varlığının prematüre ventriküler atım (PVA) sıklığıyla ilişkili olup olmadığının gösterilmesi amaçlanmıştır. Yöntemler: Ağustos 2012 ile Şubat 2013 arasında yapılan 282 adet 24 saatlik Holter retrospektif olarak değerlendirilmiştir. İlk olarak hastalar fQRS varlığı- na göre 2 gruba ayrılmış daha sonra da PVA sıklığına göre, Grup 1: seyrek PVA ( 720 PVA/gün) olacak şekilde 3 gruba ayrılmıştır. Çoklu lojistik regresyon analizi ile sık PVA belirteçleri incelenmiştir. Bulgular: Doksan sekiz hastada fQRS mevcuttu. İki grup arasında vücut kitle indeksi, cinsiyet, hipertansiyon ve şeker hastalığı açısından fark yoktu. fQRS olan hastalar daha yaşlı idi (54,9±15,6'ya karşı 47,0±16,3, p<0,001) ve ailesel koroner arter hastalığı öyküsü daha fazla idi (%25'e karşı %13, p=0,012). fQRS hastalarının aspirin kullanma oranları daha fazla idi (%28,6'ya karşı %10,4, p<0,001) ve sol atriyumları daha geniş idi (33.5±5.7 mm'e karşı 30,4±5,8 mm, p=0,001). fQRS varlığı PVA sıklığı ile anlamlı bir şekilde ilişkiliydi (Sık PVA için %27,7'ye karşı %7,6, p<0,001, orta sıklıkta PVA için %18,4'e karşı %11,4, p=0,012). Grup 1'in (n=202) %26,2'sinde, grup 2'nin (n=39) %46,2 sinde grup 3'ün (n=41) ise %65,9'unda fQRS mevcuttu. Çoklu lojistik regresyon analizinde sadece yaş (tehlike oranı: 4,24, %95 güvenlik aralığı 2,08-8,64, p=0,001) ve fQRS varlığı (tehlike oranı: 2,11, %95 güvenlik aralığı 1,00-4,45, p=0,05) sık PVA'nın bağımsız öngörücüsü olarak bulunmuştur. Sonuç: Bu çalışma göstermiştir ki, fQRS varlığı aşikar yapısal kalp hastalığı olmayanlarda sık PVA ile ilişkilidir.

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Cite This Article

TEMİZ, A., GAZİ, E., ALTUN, B., GÜNGÖR, Ö., BARUTÇU, A., BEKLER, A., TAN, Y. Z., YENER, A. Ü., SAÇAR, M., ÇÖLKESEN, Y. (2015). Aşikar yapısal kalp hastalığı olmayan hastalarda fragmente QRS prematüre ventriküler atım sıklığıyla ilişkilidir. The Anatolian Journal of Cardiology, Cilt: 15 - Sayı: 6, 456–462. https://ajindex.com/articles/365929

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