Journals / The Anatolian Journal of Cardiology / 2018 / Cilt: 19 - Sayı: 6

Role of cardiac T1 mapping and extracellular volume in the assessment of myocardial infarction

Pages
404–411
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We conclude by highlighting some of theremaining challenges such as quality control, standardization of image acquisition for clinical practice, and automated methods for quantifyinginfarct size, area at risk, and myocardial salvage post MI.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Although late gadolinium enhancement on cardiac magnetic resonance imaging remains the reference standard for scar assessment, it doesnot provide quantitative information about the extent of pathophysiological changes within the scar tissue.
📊
Key Findings & Data:T1 mapping and extracellular volume(ECV) mapping are steadily becoming diagnostic and prognostically useful tests for in vivo myocardial histology, influencing clinical decisionmaking.Quantitative native T1 maps (acquired without a contrast agent) represent the longitudinal relaxation time within the myocardium andchanges with myocardial extracellular water (edema, focal, or diffuse fibrosis), fat, iron, and amyloid protein content.
💡
Conclusion & Impact:We conclude by highlighting some of theremaining challenges such as quality control, standardization of image acquisition for clinical practice, and automated methods for quantifyinginfarct size, area at risk, and myocardial salvage post MI.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

Although late gadolinium enhancement on cardiac magnetic resonance imaging remains the reference standard for scar assessment, it doesnot provide quantitative information about the extent of pathophysiological changes within the scar tissue. T1 mapping and extracellular volume(ECV) mapping are steadily becoming diagnostic and prognostically useful tests for in vivo myocardial histology, influencing clinical decisionmaking.Quantitative native T1 maps (acquired without a contrast agent) represent the longitudinal relaxation time within the myocardium andchanges with myocardial extracellular water (edema, focal, or diffuse fibrosis), fat, iron, and amyloid protein content. Post-contrast ECV mapsestimate the size of the extracellular space and have sensitivity in the identification of interstitial disease. Both pre- and post-contrast T1 mappingare emerging as comprehensive tools for the assessment of numerous conditions including ischemic scarring that occurs post myocardialinfarction (MI). This review outlines the current evidence and potential future role of T1 mapping in MI. We conclude by highlighting some of theremaining challenges such as quality control, standardization of image acquisition for clinical practice, and automated methods for quantifyinginfarct size, area at risk, and myocardial salvage post MI.

🔖

Cite This Article

GARG, P., SAUNDERS, L. C., SWİFT, A. J., WİLD, J. M., PLEİN, S. (2018). Role of cardiac T1 mapping and extracellular volume in the assessment of myocardial infarction. The Anatolian Journal of Cardiology, Cilt: 19 - Sayı: 6, 404–411. https://ajindex.com/articles/365297

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (2)

  1. Nakamori S, Alakbarli J, Bellm S, Motiwala SR, Addae G, Manning WJ, et al. Native T 1 value in the remote myocardium is independently associated with left ventricular dysfunction in patients with prior myocardial infarction. J Magn Reson Imaging 2017; 46: 1073-81.
  2. Kali A, Cokic I, Tang RLQ, Yang HJ, Sharif B, Marbán E, et al. Determination of location, size, and transmurality of chronic myocardial infarction without exogenous contrast media by using cardiac magnetic resonance imaging at 3 T. Circ Cardiovasc Imaging 2014; 7: 471-81. [CrossRef] Garg P, Greenwood JP, Plein S. Multiparametric relaxometry by cardiac magnetic resonance imaging in Takotsubo cardiomyopathy. Eur Heart J Cardiovasc Imaging 2015; 16: 1174. [CrossRef] Garg P, Abdel-Rahman SED, Greenwood JP, Plein S. Free-Wall Rupture Post-Reperfused Acute Myocardial Infarction: Insights From Multimodality Cardiovascular Imaging. Circulation 2015; 132: e245-7. Fernández-Jiménez R, Barreiro-Pérez M, Martin-García A, Sánchez-González J, Agüero J, Galán-Arriola C, et al. Dynamic Edematous Response of the Human Heart to Myocardial Infarction: Implications for Assessing Myocardial Area at Risk and Salvage. Circulation 2017; 136: 1288-1300. [CrossRef] Chow K, Yang Y, Shaw P, Kramer CM, Salerno M. Robust freebreathing SASHA T1 mapping with high-contrast image registration. J Cardiovasc Magn Reson 2016; 18: 47. [CrossRef] Liu D, Borlotti A, Viliani D, Jerosch-Herold M, Alkhalil M, De Maria GL, et al. CMR Native T1 Mapping Allows Differentiation of Reversible Versus Irreversible Myocardial Damage in ST-Segment–Elevation Myocardial Infarction. Circ Cardiovasc Imaging 2017; 10: e005986. Garg P, Broadbent DA, Swoboda PP, Foley JRJ, Fent GJ, Musa TA, et al. Acute Infarct Extracellular Volume Mapping to Quantify Myocardial Area at Risk and Chronic Infarct Size on Cardiovascular Magnetic Resonance Imaging. Circ Cardiovasc Imaging 2017; 10: e006182. [CrossRef] Garg P, Broadbent DA, Swoboda PP, Foley JRJ, Fent GJ, Musa TA, et al. Extra-cellular expansion in the normal, non-infarcted myocardium is associated with worsening of regional myocardial function after acute myocardial infarction. J Cardiovasc Magn Reson 2017; 19: 73. [CrossRef] Carberry J, Carrick D, Haig C, Rauhalammi SM, Ahmed N, Mordi I, et al. Remote Zone Extracellular Volume and Left Ventricular Remodeling in Survivors of ST-Elevation Myocardial Infarction. Hypertension 2016; 68: 385-91. [CrossRef] Carrick D, Haig C, Rauhalammi S, Ahmed N, Mordi I, McEnteg