After 3-year follow-up for the first caseand 1-year follow-up for the second case, there was no recurrence.
📌 3 Key Takeaways
🎯
Objective & Hypothesis:Desmoplastic infantile astrocytomas (DIAs), are rare supratentorial tumors, usually observed in the first 24 months of life.
📊
Key Findings & Data:These tumors both have densefibroblastic stroma and positive staining with glial fibrillar acidic protein (GFAP) and CD34.A rare case of desmoplastic infantile astrocytoma presenting with right side partial seizures presented in a 1-year-old child.A rare case of desmoplastic infantile astrocytoma presenting with focal onset generalized seizures presented in a 1-year-old child.Despite their radiological and histological properties, these tumors have a benign course.
💡
Conclusion & Impact:After 3-year follow-up for the first caseand 1-year follow-up for the second case, there was no recurrence.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters
Özet
Desmoplastic infantile astrocytomas (DIAs), are rare supratentorial tumors, usually observed in the first 24 months of life. Despitetheir aggressive appearance, they tend to follow a favorable clinical course. Total or near total resection of tumor is usually thetreatment option. Desmoplastic Infantile Ganglioglioma (DIG) and DIA are WHO grade I tumors that have similar clinical and morphologicalfindings. The only criterion in differential diagnosis is the neural component of DIG. These tumors both have densefibroblastic stroma and positive staining with glial fibrillar acidic protein (GFAP) and CD34.A rare case of desmoplastic infantile astrocytoma presenting with right side partial seizures presented in a 1-year-old child.A rare case of desmoplastic infantile astrocytoma presenting with focal onset generalized seizures presented in a 1-year-old child.Despite their radiological and histological properties, these tumors have a benign course. After 3-year follow-up for the first caseand 1-year follow-up for the second case, there was no recurrence.
🔖
Cite This Article
TANIK, C., DEVECİOĞLU, E. G., HASÇİÇEK, S., CAN, S. M., HALEFOĞLU, A. M., KABUKÇUOĞLU, F. (2018). A Rare Tumor in Childhood Desmoplastic Infantile Astrocytoma: Two Case Reports. Şişli Etfal Hastanesi Tıp Bülteni, Cilt: 52 - Sayı: 3, 222–226. https://ajindex.com/articles/363711
Ulu MO. Tanrıöver N, Biçeroğlu H, Öz B, Canbaz B. A Case report: A noninfantile desmoplastic astrocytoma. Turk Neurosurg 2008;18:42–6.
Kaymaz M, Yılmaz MB, Güven Ç, Emmez ÖH, Baykaner K. Desmoplastic Infantile Astrocytoma Diagnosed after Simple Partial Seizure: A Case Report and Review of Literature. Türk Nöroşirüji Dergisi 2011;21:257–61.
Kato M, Yano H, Okumura A, Shinoda J, Sakai N, Shimokawa K. A non-infantile case of desmoplastic infantile astrocytoma. Childs Nerv Syst 2004;20:499–501. Louis DN, von Deimling A, Dickersin GR, Dooling EC, Seizinger BR. Desmoplastic cerebral astrocytomas of infancy: a histopathologic, immunohistochemical, ultrastructural, and molecular genetic study. Hum Pathol 1992;23:1402–9. de Chadarévian JP, Pattisapu JV, Faerber EN. Desmoplastic cerebral astrocytoma of infancy. Light microscopy, immunocytochemistry, and ultrastructure. Cancer 1990;66:173–9.
Bianchi F, Tamburrini G, Massimi L, Caldarelli M. Supratentorial tumors typical of the infantile age: desmoplastic infantile ganglioglioma (DIG) and astrocytoma (DIA). A review. Childs Nerv Syst 2016;32:1833–8.
Mallucci C, Lellouch-Tubiana A, Salazar C, Cinalli G, Renier D, Sainte- Rose C, et al. The management of desmoplastic neuroepithelial tumours in childhood. Childs Nerv Syst 2000;16:8–14.
Trehan G, Bruge H, Vinchon M, Khalil C, Ruchoux MM, Dhellemmes P, et al. MR imaging in the diagnosis of desmoplastic infantile tumor: retrospective study of six cases. AJNR Am J Neuroradiol 2004;25:1028–33.
Rypens F, Esteban MJ, Lellouch-Tubiana A, Bastien-Fagnou C, Renier D, Baraton J, et al. Desmoplastic supratentorial neuroepithelial tumours of childhood: imaging in 5 patients. Neuroradiology 1996;38 Suppl 1:S165–8. Rasalkar DD, Paunipagar BK, Ng A. Primary spinal cord desmoplastic astrocytoma in an adolescent: a rare tumour at rare site and rare age. Hong Kong Med J 2012;18:253–5.
Santhosh K, Kesavadas C, Radhakrishnan VV, Abraham M, Gupta AK. Multifocal desmoplastic noninfantile astrocytoma. J Neuroradiol 2008;35:286–91.
Raz E, Zagzag D, Saba L, Mannelli L, Di Paolo PL, D'Ambrosio F, et al. Cyst with a mural nodule tumor of the brain. Cancer Imaging 2012;12:237–44.
Aghi MK, Carter BS, Cosgrove GR, Ojemann RG, Amin-Hanjani S, Martuza RL, et al. Long-term recurrence rates of atypical meningiomas after gross total resection with or without postoperative adjuvant radiation. Neurosurgery 2009;64:56–60.
Tihan T, Viglione M, Rosenblum MK, Olivi A, Burger PC. Solitary fibrous tumors in the ce