Journals / The Journal of Pediatric Research / 2019 / Cilt: 6 - Sayı: 1

Diagnostic Value of the Mean Platelet Volume in the Prediction of Respiratory Syncytial Virus in Acute Bronchiolitis

Pages
51–55
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

However, the measurement of MPV might not be correct and sufficient to provide a prediction on the types of respiratory viruses in bronchiolitis.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: Respiratory syncytial virus (RSV) is a viral pathogen that causes lower respiratory system infections in childhood.
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Key Findings & Data:The purpose of this study was to examine whether mean platelet volume (MPV) changes are significant in the prediction of RSV bronchiolitis.Materials and Methods: One hundred and eighty-four infants who were diagnosed with acute bronchiolitis were divided into groups based on being RSV positive and other respiratory viruses positive.
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Conclusion & Impact:However, the measurement of MPV might not be correct and sufficient to provide a prediction on the types of respiratory viruses in bronchiolitis.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

Aim: Respiratory syncytial virus (RSV) is a viral pathogen that causes lower respiratory system infections in childhood. The purpose of this study was to examine whether mean platelet volume (MPV) changes are significant in the prediction of RSV bronchiolitis.Materials and Methods: One hundred and eighty-four infants who were diagnosed with acute bronchiolitis were divided into groups based on being RSV positive and other respiratory viruses positive. Using the receiver operating characteristic (ROC), diagnostic accuracy was evaluated according to the areas under the curves (AUC) for the diagnosis of bronchiolitis. A p value of 0.05) and other viruses. ROC curve analysis indicates that the MPV level cut-off point for making the diagnosis of single RSV bronchiolitis was 6.63 fL with a sensitivity and specificity of 55% and 63% respectively. The median AUC was 0.384 for the MPV (95% CI 0.270-0.499, p=0.04).Conclusion: Volume of MP may be a useful marker to provide a prediction on single RSV bronchiolitis. However, the measurement of MPV might not be correct and sufficient to provide a prediction on the types of respiratory viruses in bronchiolitis.

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Cite This Article

GÖKÇE, Ş., KURUGÖL, Z., KOTUROĞLU, G., ASLAN, A., POLATER, S., SAYDAM, C. Ç. (2019). Diagnostic Value of the Mean Platelet Volume in the Prediction of Respiratory Syncytial Virus in Acute Bronchiolitis. The Journal of Pediatric Research, Cilt: 6 - Sayı: 1, 51–55. https://ajindex.com/articles/362897

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References (14)

  1. World Health Organization. WHO Consultation on respiratory syncytial virus (RSV) vaccine development. http://www.who. int/immunization/research/meetings_workshops/rsv_ vaccine_ development/en/(Accessed 5 June, 2017)
  2. World Health Organization. Research and Development. http:// www.who.int/immunization/research/meetings_workshops/ rsv_vaccine_development/en/(Accessed 5 June 5, 2017)
  3. Black-Payne C. Bronchiolitis, in: Hilman BC. (Eds.), Pediatric Respiratory Disease: Diagnosis and Treatment, Philadelphia, PA: WB Saunders,1993, pp. 205-218
  4. Berry M, Gamieldien J, Fielding BC. Identification of new respiratory viruses in the millennium. Viruses 2015;7:996-1019
  5. Morrell CN, Aggrey AA, Chapman LM, Modjeski KL. Emerging roles for platelets as immune and inflammatory cells. Blood 2014;123:2759-67
  6. Bilici S, Sekmenli T, Goksu M, Melek M, Avci V. Mean platelet volume in diagnosis of acute appendicitis in children. Afr Health Sci 2011;11:427-32
  7. Beyazit Y, Sayilir A, Torun S, et al. Mean platelet volume as an indicator of disease severity in patients with acute pancreatitis. Clin Res Hepatol Gastroenterol 2012;36:162-8
  8. Karadag-Oncel E, Ozsurekci Y, Kara A, Karahan S, Cengiz AB, Ceyhan M. The value of mean platelet volume in the determination of community acquired pneumonia in children. Ital J Pediatr 2013;39:16
  9. Sahin F, Yazar E, Yıldız P. Prominent features of platelet count, plateletcrit, mean platelet volume and platelet distribution width in pulmonary tuberculosis. Multidiscip Respir Med 2012;7:38
  10. Tozkoparan E, Deniz O, Ucar E, Bilgic H, Ekiz K. Changes in platelet count and indices in pulmonary tuberculosis. Clin Chem Lab Med 2007;45:1009-13
  11. Ergül AB, Torun YA, Uytun S, Aslaner H, Kısaaslan AP, Şerbetçi MC. Reduction in mean platelet volume in children with acute bronchiolitis. Turk Pediatri Ars 2016;51:40-5
  12. Renshaw AA, Drago B, Toraya N, Gould EW. Respiratory syncytial virus infection is strongly correlated with decreased mean platelet volume. International Journal of Infectious Diseases. 2013;17:678-80
  13. American Academy of Pediatrics Subcommittee on Diagnosis and Management of Bronchiolitis, Diagnosis and management of bronchiolitis. Pediatrics. 2006;118:1774-93
  14. Bezerra PG, Britto MC, Correia JB, et al. Viral and atypical bacterial detection in acute respiratory infection in children under five years. PLoS One 2011;6:18928.