Journals / Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi / 2026 / Volume: 11 Issue: 1

Primary Active Epstein-Barr Virus Infection Coexisting with Immune Thrombocytopenia in Children-A Rare Trigger Factor of Immun Thrombocytopenia: Two Case Reports

Şule Gökçe(EGE UNIVERSITY, EGE FACULTY OF MEDICINE)0000-0003-3392-4990
Merve Tosyalı(EGE UNIVERSITY, EGE FACULTY OF MEDICINE)0000-0002-7920-1491
Aykut Şafaklı(EGE UNIVERSITY, EGE FACULTY OF MEDICINE)0009-0003-5015-4964
Rıza Yıldırım(EGE UNIVERSITY, EGE FACULTY OF MEDICINE)0009-0000-2675-1150
Necla Burcu Koçer Ahmadov(EGE UNIVERSITY, EGE FACULTY OF MEDICINE)0009-0003-5797-5714
Gizem Tunçalp(EGE UNIVERSITY, EGE FACULTY OF MEDICINE)0009-0007-2318-5115
Nur Bostancı(EGE UNIVERSITY, EGE FACULTY OF MEDICINE)0009-0001-5516-2088
Ayla Mammadova(EGE UNIVERSITY, EGE FACULTY OF MEDICINE)0009-0002-1783-3546
Elif Gökçe Çelebi(EGE UNIVERSITY, EGE FACULTY OF MEDICINE)0009-0001-4377-7843
Nida Nur Şahin(EGE UNIVERSITY, EGE FACULTY OF MEDICINE)0009-0009-3595-8685
Çağla Türksönmez(EGE UNIVERSITY, EGE FACULTY OF MEDICINE)0009-0005-5917-1220
Aylin Erol(EGE UNIVERSITY, EGE FACULTY OF MEDICINE)0009-0007-3251-7222
Hüseyin Orkun Köse(EGE UNIVERSITY, EGE FACULTY OF MEDICINE)0009-0001-9403-4775
Feyza Umay Koç(EGE UNIVERSITY, EGE FACULTY OF MEDICINE)0000-0002-5891-8506
Pages
—
Publication Date
2024-03-27
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Here, we discuss two cases with ITP secondary Epstein barr virus infection.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Immune thrombocytopenia (ITP) is a reason of thrombocytopenia that is characterized by isolated thrombocytopenia in childhood.
📊
Key Findings & Data:Epstein barr virus infection (EBV) is a mildly and uncomplicated ailment that might be a trigger factor for ITP.
💡
Conclusion & Impact:Here, we discuss two cases with ITP secondary Epstein barr virus infection.
🔬Design:Case Report
📍Scope:Comprehensive Sample
⚙️Variables:Immun thrombocytopenia · Epstein-Barr virus · children

Abstract

Immune thrombocytopenia (ITP) is a reason of thrombocytopenia that is characterized by isolated thrombocytopenia in childhood. Epstein barr virus infection (EBV) is a mildly and uncomplicated ailment that might be a trigger factor for ITP. Here, we discuss two cases with ITP secondary Epstein barr virus infection.

Özet

İmmün trombositopeni (ITP), çocukluk çağında izole trombositopeni ile karakterize bir trombositopeni nedenidir. Epstein barr virüs enfeksiyonu (EBV) ITP için tetikleyici bir faktör olabilecek hafif ve komplikasyonsuz bir hastalıktır. Burada, Epstein barr virüs enfeksiyonuna ikincil ITP gelişen iki olgu tartışılmıştır.

🔖

Cite This Article

Gökçe, Ş., Tosyalı, M., Şafaklı, A., Yıldırım, R., Ahmadov, N. B. K., Tunçalp, G., Bostancı, N., Mammadova, A., Çelebi, E. G., Şahin, N. N., Türksönmez, Ç., Erol, A., Köse, H. O., Koç, F. U. (2024). Primary Active Epstein-Barr Virus Infection Coexisting with Immune Thrombocytopenia in Children-A Rare Trigger Factor of Immun Thrombocytopenia: Two Case Reports. Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi, Volume: 11 Issue: 1. https://doi.org/10.34087/cbusbed.1433575

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (9)

  1. Rodeghiero F, Stasi R, Gernsheimer T, et al. Standardization of terminology, definitions and outcome criteria in immune thrombocytopenic purpura of adults and children: report from an international working group. Blood 2009; 113:2386–2393.
  2. Correia S, Bridges R, Wegner F, et al. Sequence Variation of Epstein-Barr Virus: Viral Types, Geography, Codon Usage, and Diseases. J Virol 2018; 92: e01132-18.
  3. Pipp ML, Means ND, Sixbey JW, Morris KL, Gue CL, Baddour LM. Acute Epstein- Barr virus infection complicated by severe thrombocytopenia. Clin Infect Dis 1997; 25:1237–9.
  4. Zeller B, Rajantie J, Hedlund-Treutiger I, et al. Childhood idiopathic thrombocytopenic purpura in the Nordic countries: epidemiology and predictors of chronic disease. Acta Paediatr 2005; 94:178-84.
  5. Chiang MR, Wei CC, Muo CS, Fu LS, Li TC, Kao CH. Association of primary immune thrombocytopenia and common allergic diseases among children. Pediatr Res 2015; 77:597-601.
  6. Ebell MH. Epstein-Barr virus infectious mononucleosis. Am Fam Physician 2004; 70:1279-87.
  7. Elalfy MS, Nugent D. Viruses, anti-viral therapy, and viral vaccines in children with immune thrombocytopenia. Semin Hematol 2016; 53:70-72.
  8. Nielsen TR, Rostgaard K, Nielsen NM, et al. Multiple sclerosis after infectious mononucleosis. Arch Neurol 2007; 64:72-75.
  9. Norris PAA, Kaur G, Lazarus AH. New insights into IVIg mechanisms and alternatives in autoimmune and inflammatory diseases. Curr Opin Hematol 2020; 27:392-398