Journals / The European Research Journal / 2018 / Cilt: 4 - Sayı: 2

How to diagnose neuropathy in diabetes mellitus?

Pages
55–69
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The aim of the present review was to evaluate evidence-based diagnosis for any type of neuropathy seen in the patients with diabetes mellitus.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Diabetic neuropathy is a common problem and can present various clinical presentations such as cranial neuropathy, radiculopathy, plexopathy, mononeuropathy, polyneuropathy and autonomic neuropathy.
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Key Findings & Data:The early diagnosis is crucial because it is well-known that subclinical diabetic neuropathy may be reversed or significantly improved with diabetes control.
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Conclusion & Impact:The aim of the present review was to evaluate evidence-based diagnosis for any type of neuropathy seen in the patients with diabetes mellitus.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:length-dependent sensorimotor polyneuropathy · small fiber · nerve conduction studies

Abstract

Diabetic neuropathy is a common problem and can present various clinical presentations such as cranial neuropathy, radiculopathy, plexopathy, mononeuropathy, polyneuropathy and autonomic neuropathy. Clinical evaluation and use of scoring systems for the evaluation of diabetic polyneuropathy is an important step to get correct diagnosis. New informations about the diagnosis of diabetic neuropathy continue to emerge, which will lead to correct diagnosis and treatment as well. Diabetic length-dependent sensorimotor polyneuropathy (DSPN) and carpal tunnel syndrome are the most common seen problems. While acute and painful situations with motor weakness are mostly transient, sensory fibres are predominantly involved in chronic ones. Nerve conduction studies are needed to confirm diagnosis of any type of diabetic neuropathy, but they are normal in cases with small fiber involvement. The early diagnosis is crucial because it is well-known that subclinical diabetic neuropathy may be reversed or significantly improved with diabetes control. Because neuropathy at the stage in which only small fibers are affected can be reversed, it is important to diagnose DSPN in these stages. Skin biopsy taken from the dermatomal area of sural nerve, laser-doppler-imager flare technique, corneal confocal microscopy are used to assess small fibre dysfunction. The aim of the present review was to evaluate evidence-based diagnosis for any type of neuropathy seen in the patients with diabetes mellitus.

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Cite This Article

KOÇER, A. (2018). How to diagnose neuropathy in diabetes mellitus?. The European Research Journal, Cilt: 4 - Sayı: 2, 55–69. https://ajindex.com/articles/361356

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References (14)

  1. Deli G, Bosnyak E, Pusch G, Komoly S, Feher G. Diabetic neuropathies: diagnosis and management. Neuroendocrinology 2013;98:267-80
  2. Thomas PK. Classification, differential diagnosis and staging of diabetic peripheral neuropathy. Diabetes 1997;46:54-7
  3. Boulton AJ, Vinik AI, Arezzo JC, Bril V, Feldman EL, Freeman R, et al.; American Diabetes Association. Diabetic neuropathies: a statement by the American Diabetes Association. Diabetes Care 2005;28:956-62
  4. Gupta A, Gupta Y. Diabetic neuropathy: Part 1. J Pak Med Assoc 2014;64:714-8
  5. Dyck PJ, Kratz KM, Karnes JL, Litchy WJ, Klein R, Pach JM, et al. The prevalence by staged severity of various types of diabetic neuropathy, retinopathy, and nephropathy in a population-based cohort: the Rochester Diabetic Neuropathy Study. Neurology 1993;43:817-24
  6. Pasnoor M, Dimachkie MM, Kluding P, Barohn RJ. Diabetic neuropathy part 1: overview and symmetric phenotypes. Neurol Clin 2013;31:425-45
  7. Tesfaye S, Boulton AJM, Dyck PJ, Freeman R, Horowitz M, Kempler P, et al.; Toronto Diabetic Neuropathy Expert Group. Diabetic Neuropathies: Update on Definitions, Diagnostic Criteria, Estimation of Severity, and Treatments. Diabetes Care 2010;33:2285-93
  8. Dyck PJ, Davies JL, Clark VM, Litchy WJ, Dyck PJ, Klein CJ, et al. Modeling chronic glycemic exposure variables as correlates and predictors of microvascular complications of diabetes. Diabetes Care 2006;29:2282-8
  9. Ali A, Iqbal F, Taj A, Iqbal Z, Amin MJ, Iqbal QZ. Prevalence of microvascular complications in newly diagnosed patients with type 2 diabetes. Pak J Med Sci 2013;29: 899-902
  10. Wild S, Roglic G, Green A, Sicree R, King H. Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care 2004;27:1047-53
  11. Zilliox L, Russell JW. Treatment of diabetic sensory polyneuropathy. Curr Treat Options Neurol 2011;13:143-59
  12. Smith AG, Russell J, Feldman EL, Goldstein J, Peltier A, Smith S, et al. Lifestyle intervention for pre-diabetic neuropathy. Diabetes Care 2006;29:1294-9
  13. Albers JW, Herman WH, Pop-Busui R, Martin CL, Cleary P, Waberski B; Diabetes Control and Complications Trial (DCCT)/Epidemiology of Diabetes Intervention and Complications (EDIC) Research Group. Subclinical neuropathy among Diabetes Control and Complications Trial participants without diagnosable neuropathy at trial completion: possible predictors of incident neuropathy? Diabetes Care 2007;30:2613-8
  14. Treede RD, Jensen TS, C