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Journals / The European Research Journal / 2015 / Cilt: 1 - Sayı: 1

The effect of perimenopausal estrogen levels on depression and anxiety: a pilot study

Buket Belkız GÜNGÖR
Mahmut GÜNGÖR
İbrahim TAYMUR
Rüstem AŞKIN
Hakan DEMİRCİ
Yakup AKPINAR
Almıla İkra AKGÜL
Pages
8–13
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The possible role of estrogen replacement in the treatment of depression and anxiety should be investigated in further studies.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Among women in the perimenopausal period, rapid hormonal changes can be seen.
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Key Findings & Data:The research group was composed of 30 perimenopausal women who had FSH levels higher than 20 IU and irregular menses.
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Conclusion & Impact:The possible role of estrogen replacement in the treatment of depression and anxiety should be investigated in further studies.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Perimenopause · depression · anxiety

Abstract

Objectives. Among women in the perimenopausal period, rapid hormonal changes can be seen. In the present study, we aimed to investigate the relationship between depression, anxiety and changing estrogen hormone levels at menopause. Materials and Methods. The research group was composed of 30 perimenopausal women who had FSH levels higher than 20 IU and irregular menses. Anxiety and depression status was assessed with the Hospital Anxiety and Depression Scale. Patients with or without depression or serious anxiety were compared in terms of age, body mass index (BMI), hot flushes, smoking, premenstrual syndrome (PMS) and estrogen levels. Results. There were no statistically significant differences in terms of hot flushes, BMI, smoking, age, and PMS in patients with or without depression/anxiety. Estrogen levels were statistically significantly lower in the group with depression compared to the group without depression (p=0.026). Conclusion. We believe that falling levels of estrogen in the perimenopausal period can be considered to be a risk factor for depression. The possible role of estrogen replacement in the treatment of depression and anxiety should be investigated in further studies.

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Cite This Article

GÜNGÖR, B. B., GÜNGÖR, M., TAYMUR, İ., AŞKIN, R., DEMİRCİ, H., AKPINAR, Y., AKGÜL, A. İ. (2015). The effect of perimenopausal estrogen levels on depression and anxiety: a pilot study. The European Research Journal, Cilt: 1 - Sayı: 1, 8–13. https://ajindex.com/articles/361274

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