Journals / Acta Orthopaedica et Traumatologica Turcica / 2005 / Cilt: 39 - Sayı: 5

Treatment of simple bone cysts with methylprednisolone acetate in children

Çocukluk çağındaki basit kemik kistlerinin metilprednisolon asetat ile tedavisi

Pages
411–415
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Our results suggest that treatment with steroid injections offers satisfactory outcome in simple bone cysts in children, and thus, is worthy of consideration before more aggressive methods are to be applied.

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: Steroid injections represent one of the simple treatment alternatives for simple bone cysts in pediatric age group.
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Key Findings & Data:Methods: Thirteen children (9 boys, 4 girls; mean age 9 years; range 4 to 14 years) with simple bone cysts were treated primarily with injection of methylprednisolone acetate with the use of the two-needle technique.
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Conclusion & Impact:Conclusion: Our results suggest that treatment with steroid injections offers satisfactory outcome in simple bone cysts in children, and thus, is worthy of consideration before more aggressive methods are to be applied.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Çocuk · Kemik kistleri · Terapötik kullanım

Abstract

Objectives: Steroid injections represent one of the simple treatment alternatives for simple bone cysts in pediatric age group. The aim of this study was to evaluate the results of steroid injections in the treatment of simple bone cysts. Methods: Thirteen children (9 boys, 4 girls; mean age 9 years; range 4 to 14 years) with simple bone cysts were treated primarily with injection of methylprednisolone acetate with the use of the two-needle technique. The cysts were localized in the proximal humerus (n=7), femoral intertrochanteric region (n=4), and the proximal one-third of the femur (n=1). Four patients had fractures before treatment. Each patient received a maximum of three injections at six-week intervals, each consisting of 120-160 mg of methylprednisolone acetate. The patients were monitored by plain radiographs obtained in the sixth week, third month, sixth month, and at the end of a year followed by annual radiographic evaluations. Cyst healing was assessed according to the Neer classification. The mean follow-up was five years (range 1 to 11 years). Results: Treatment with methylprednisolone acetate resulted in complete healing in five patients (38.5%) and healing with residual lesions in six patients (46.2%). One patient (7.7%) did not respond to steroid treatment and one patient developed recurrence. The results were satisfactory (84.6%) in patients with complete healing and healing with residual lesions, and unsatisfactory in two patients (15.4%). No procedure-related complications were encountered. Conclusion: Our results suggest that treatment with steroid injections offers satisfactory outcome in simple bone cysts in children, and thus, is worthy of consideration before more aggressive methods are to be applied.

Özet

Amaç: Çocukluk çağında görülen basit kemik kistlerinde kist içine steroid enjeksiyonu basit tedavi seçeneklerinden biridir. Bu çalışmada, basit kemik kistlerinin tedavisinde steroid enjeksiyonunun sonuçları değerlendirildi. Çalışma planı: Basit kemik kisti saptanan 13 çocuk hasta (9 erkek, 4 kız; ort. yaş 9; dağılım 4-14) iki iğne tekniği kullanılarak kist içine metilprednisolon asetat enjeksiyonuyla tedavi edildi. Kist yedi olguda humerus proksimali, dört olguda femur intertrokanterik bölge, bir olguda 1/3 proksimal femur cisminde yerleflmiflti. Dört hastada steroid enjeksiyonu öncesinde patolojik kırık oluşmuştu. Hastalara altı hafta arayla, herbiri 120-160 mg metilprednisolon asetat içeren en fazla üç enjeksiyon uygulandı. Enjeksiyon sonrasında altıncı haftada, üçüncü ayda, altıncı ayda ve birinci yılda düz grafiler çekildi. ilk yıldan sonra hastalar yılda bir kez grafilerle takip edildi. Kist iyileşmesi Neer sınıflandırmasına göre değerlendirildi. Hastaların ortalama takip süresi 5 yıl (dağılım 1-11 yıl) idi. Sonuçlar: Metilprednisolon asetat tedavisi befl hastada (%38.5) tamamen, alt› hastada (%46.2) rezidüel lezyonla iyileşme sağlad›. Bir hasta (%7.7) steroide hiç yanıt vermedi; bir hastada kist tekrarladı. Tamamen veya rezidüel lezyonla iyileşen hastalardaki sonuçlar tatminkar bulunurken (%84.6), iki hastada (%15.4) başarısız bulundu. işlemle ilgili hiçbir hastada komplikasyon görülmedi. Çıkarımlar: Bulgularımız, çocuklarda görülen basit kemik kistlerinde steroid enjeksiyonunun tatmin edici sonuçlar sağladığını ve agresif tedaviler öncesinde düşük morbiditeli bu tedavinin denenebileceğini göstermektedir.

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Cite This Article

YILMAZ, G., AKSOY, M. C., ALANAY, A., YAZICI, M., ALPASLAN, A. M. (2005). Treatment of simple bone cysts with methylprednisolone acetate in children. Acta Orthopaedica et Traumatologica Turcica, Cilt: 39 - Sayı: 5, 411–415. https://ajindex.com/articles/353918

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