Journals / Acta Orthopaedica et Traumatologica Turcica / 2007 / Cilt: 41 - Sayı: 2

Dissemination pathways in high-pressure injection injuries of the hand: An experimental animal model

Elin yüksek basınçlı enjeksiyon yaralanmalarında dağılım yolları: Deneysel hayvan modeli

Pages
147–151
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Our results suggest that, in addition to the tissues mentioned in the literature, neurovascular bundles are primarily and seriously affected by high-pressure injection injuries of the hand.

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: High-pressure injection injuries of the hand may compromise the function of the hand or even result in amputations.
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Key Findings & Data:Based on our clinical observations, we aimed to demonstrate neurovascular dissemination in an animal model.
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Conclusion & Impact:Conclusion: Our results suggest that, in addition to the tissues mentioned in the literature, neurovascular bundles are primarily and seriously affected by high-pressure injection injuries of the hand.
🔬Design:Modeling & Simulation
📍Scope:Comprehensive Sample
⚙️Variables:Modeller · hayvan · Debridman

Abstract

Objectives: High-pressure injection injuries of the hand may compromise the function of the hand or even result in amputations. Based on our clinical observations, we aimed to demonstrate neurovascular dissemination in an animal model. Methods: Ten adult New Zealand rabbits with a mean weight of 200 g were used. Under xylazine-ketamine anesthesia and using a triple connection system, the rabbits were injected one milliliter of black Indian ink in the third finger tip of the upper limbs at 4 atmospheric pressure. The rabbits were sacrificed via intracardiac injections for transhumeral amputation of all the upper limbs. All amputations were fixed in 10% formalin, decalcified, and specimens obtained from fingers and distal and proximal regions of the wrist were stained with hematoxylin and eosin for histopathologic examination. Results: Transverse sections of the third finger showed subcutaneous deposition of Indian ink particularly in the pulp in all the specimens. In addition, all specimens from the distal wrist showed penetration into fascia, tendon sheaths, and neurovascular bundles of the third finger. Conclusion: Our results suggest that, in addition to the tissues mentioned in the literature, neurovascular bundles are primarily and seriously affected by high-pressure injection injuries of the hand.

Özet

Amaç: Yüksek basınçlı enjeksiyon yaralanmaları, el işlevlerinde ileri derecede kayıplara, hatta amputasyonlara neden olmaktadır. Bu çalışmada klinik uygulamalarda gözlemlediğimiz nörovasküler yayılımın deneysel çalışma ile gösterilmesi amaçlandı. Çalışma planı: Çalışmada ortalama 200 gr ağırlıkta 10 adet erişkin Yeni Zelanda tavşanı kullanıldı. Ksilazin hidroklorid ve ketamin anestezisi altında, üçlü musluk bağlantı sistemi yardımıyla 1 ml siyah çini mürekkebi 4 atmosfer basınç altında enjektör iğnesiyle her iki üst ekstremite üçüncü parmak pulpasından uygulandı. İntrakardiyak enjeksiyonla deneklerin yaşamı sonlandırıldı. Toplam 20 adet üst ekstremite transhumeral kesildi. Elde edilen amputatlar %10’luk formalin solüsyonu içinde tespit edildi. Dekalsifikasyonu takiben amputatlardan parmak, bilek distal ve proksimalinden çeşitli seviyelerde örnekler alındı. Doku kesileri hematoksilen-eozin ile boyandıktan sonra incelendi. Sonuçlar: Parmak seviyesinden yapılan transvers kesitlerde tüm örneklerde çini mürekkebinin öncelikle pulpada cilt altında toplandığı görüldü. Tüm örneklerde bilek distalinde üçüncü parmağın tendon kılıfları ile birlikte damar sinir yapılarının da çini mürekkebiyle boyandığı görüldü. Çıkarımlar: Çalışmamızın bulguları, elin yüksek basınçlı enjeksiyon yaralanmalarında, literatürde belirtilen dokulara ek olarak, damar sinir paketlerinin de öncelikle ve ciddi şekilde etkilendiğini göstermektedir.

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Cite This Article

BEKLER, H., GÖKÇE, A., BEYZADEOĞLU, T. B. (2007). Dissemination pathways in high-pressure injection injuries of the hand: An experimental animal model. Acta Orthopaedica et Traumatologica Turcica, Cilt: 41 - Sayı: 2, 147–151. https://ajindex.com/articles/353890

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