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Journals / Dicle Tıp Dergisi / 2007 / Cilt: 34 - Sayı: 3

Prospective analysis of 183 cases who under go for amniocentesis of genetic karyotyping

Genetik amaçlı amniyosentez uygulanan 183 olgunun prospektif analizi

Mehmet ERDEMOĞLU
Ahmet KALE
Pages
170–175
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Amniocentesis is a safe and easily performed prenatal diagnosis and treatment method in modern perinatology.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The aim of this study was to evaluate the results of 183 aminocentesis cases for chromosomal analysis in high risk pregnant patients which were performed in our clinic during 2004 and 2005.
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Key Findings & Data:Fetal chromosomal anomaly ratio was 4.91%.
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Conclusion & Impact:Amniocentesis is a safe and easily performed prenatal diagnosis and treatment method in modern perinatology.
🔬Design:Research Article
📍Scope:2004 Verileri
⚙️Variables:İleriye dönük çalışma · Doğum öncesi tanı · Amniyosentez

Abstract

The aim of this study was to evaluate the results of 183 aminocentesis cases for chromosomal analysis in high risk pregnant patients which were performed in our clinic during 2004 and 2005. Amniocentesis procedure was performed mainly for, positive triple screening test and advanced maternal age . Fetal chromosomal anomaly ratio was 4.91%. The invasive procedure success rate was %97.2 for the first time. The complication was not seen to the procedure. Amniocentesis is a safe and easily performed prenatal diagnosis and treatment method in modern perinatology.

Özet

Yüksek riskli gebeliklerde fetal kromozom analizi sonuçlarının incelenmensi amacıyla, Dicle Üniversitesinde Ocak 2004-Aralık 2005 tarihleri arasında aminosentez yapılan 183 olgu değerlendirildi. Amniosentez serisinde endikasyonların büyük çoğunluğunu pozitif üçlü test ve ileri yaş olguları oluşturdu. Bu endikasyonlarda % 4.91 oranında fetal kromozom anomalisine rastlandı. Tek girişimlerdeki başarı oranı %97.2 olarak saptandı. Girişimlere bağlı olarak herhangi bir komlikasyon izlenmedi. Sonuç olarak amniosentez modern perinatolojide emniyetli ve uygulanması kolay bir prenatal tanı ve tedavi yöntemidir.

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Cite This Article

ERDEMOĞLU, M., KALE, A. (2007). Prospective analysis of 183 cases who under go for amniocentesis of genetic karyotyping. Dicle Tıp Dergisi, Cilt: 34 - Sayı: 3, 170–175. https://ajindex.com/articles/349289

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References (16)

  1. Beksaç MS. Fetal Tıp; Prenetal Tanı. Ankara, Medical Network, 1996: 29 -38
  2. Crane JP, Beaver HA, Cheung SW. First Trimester Chorionic Villus Sampling versus Midtrimester Genetic Amniocentesis. Preliminary Results of a Controlled Prospective Trial. Prenat Diagn 1988;8: 355-359 3. Lynch L, Berkowitz RL. Amniocentesis, Skin Biopsy, Umblical Cord Blood Sampling in the Prenatal Diagnosis of Genetic Disorders. In Reece EA, Hobbins JC. Mahoney MJ.(eds): Medicine of the Fetus and Mother. Philadelphia JB. Lippincott, 1992: 641-652
  3. Antsaklis A, Papantoniou N, Xygakis A, et all. S: Genetic Amniocentesis in Women 20-34 Year old Associated Risks. Prenat Diagn 2000; 20: 247-250
  4. Crandall BF, Howard J, Lebherz T, et all. Follow-up 2000 Second Trimester Amniocenteses. Obstet Gynecol 1980; 59: 625-628
  5. Evans MI, O’Brien JE, Dvorin E. Biochemical Screening. Curr Opin Obstet Gynecol 1994; 6: 453-458
  6. Yayla M, Bayhan G, Yalınkaya A, et all. Yüksek Riskli Gebelerde II. Trimester Genetik Amniyosentez: 165 olgunun klinik değerlendirilmesi Perinatoloji Dergisi. 1999; 7:140-146
  7. Tongsong T, Wanapirak C, et all. Amniocentesis-related fetal loss; a cohort study. Obstet Gynecol 1998; 92: 64-67
  8. Donnenfeld AE, Carison DE. Palomaki GE, et all. Prospective multicenter study of second-trimester nuchal skin fold thickness in unaffected and Down syndrome pregnancies. Obstet Gynecol. 1994; 84: 844-847
  9. Akbaş SH, Özben T, Alper O, ve ark. Maternal serum screning for Down syndrome, open neural tube defects and trisomi 18. Clin Chem Lab Med 2001; 39: 487-490
  10. Tabor A, Madsen M, Philip J. Randomised Controlled Trial of Genetic Amniocentesis in 4606 low risk women. Lancet 1986; 1: 1287-1293
  11. Hockstein S, Chen PX. Factors associated with maternal cell contaminiations in amniocentesis samples. Obstet Gynecol 1988; 92: 551-556
  12. Allen R. The Significance of Meconium in Midtrimester Genetic Amniocentesis. Am J Obstet Gynecol 1985; 152: 413-417
  13. Working Party on Amniocentesis: An Assessment of Hazards of Amniocentesis. Turnboll AC, Fainveather DV, Hibbard M. Br J Obstet Gynaecol 1978; 85: 1-7
  14. Golbus MS, Loughman WD, Epstein CJ. Prenatal Genetic Diagnosis in 3000 Amniocentesis. N. Engl J Med 1979; 157: 300-309
  15. Johnson JM, Wilson RD, Singer J, et all. Technical factors in early amniocentesis predict adverse outcome. Results of the Canadian Early (EA) versus midtrimester (MA) Amniocentesis Trial. Prenat Diagn 1999;19:732-738
  16. Eiben B, Hammans W,