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Journals / Dicle Tıp Dergisi / 2009 / Cilt: 36 - Sayı: 1

Endocrine disruptors and their effects on puberty

Endokrin çevre bozucular ve ergenlik üzerine etkileri

SEMRA ÇETİNKAYA
Pages
59–66
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this review, we aimed to assess on exposure to endocrine disruptors and the effects of endocrine disruptors on puberty.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Endocrine disruptors and their possible impact on human health have become a topic of discussion.
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Key Findings & Data:Endocrine disruptors affect the reproductive system and they may be responsible for oligospermia, abnormality of sperm characteristics, disorders of testicular steroidogenesis, testicular atrophy, uterus weight increases and precocious puberty.
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Conclusion & Impact:In this review, we aimed to assess on exposure to endocrine disruptors and the effects of endocrine disruptors on puberty.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Endocrine disruptors and their possible impact on human health have become a topic of discussion. Endocrine disrupting chemicals are found in plastics, detergents, pesticides and industrial chemicals. Some of these persist in the environment and others do not. Some are lipophilic, sequestered in adipose tissue and secreted in milk, and others may only be present for short periods of time but at critical periods of development. Endocrine disruptors are defined as an extrogenous substance or mixture that alters the function of the endocrine system and consequently causes adverse health effects in an intact organism, or its progeny. Endocrine disruptors affect the reproductive system and they may be responsible for oligospermia, abnormality of sperm characteristics, disorders of testicular steroidogenesis, testicular atrophy, uterus weight increases and precocious puberty. In this review, we aimed to assess on exposure to endocrine disruptors and the effects of endocrine disruptors on puberty.

Özet

Endokrin çevre bozucular ve onların insan sağlığı üzerine olası etkileri giderek tartışmaların odağı haline gelmektedir. Endokrin çevre bozan kimyasallar; plastiklerde, deterjanlarda, böcek ilaçlarında ve endüstriyel kimyasallarda bulunmaktadırlar. Bunların bazıları çevrede kalır, bazıları kalmaz. Bazıları lipofiliktir ve yağ dokusunda birikir ve süte salınır, bazıları sadece kısa bir zaman için, ama gelişimin kritik bir periyodu sırasında rol alır. Endokrin çevre bozucu; endokrin sistemin çalışmasını değiştiren ve sonunda sağlıklı organizmada veya onun nesillerinde sağlık üzerine ters etkilere neden olan, dışardan alınan madde veya bileşikler olarak tanımlanır. Endokrin çevre bozucu üreme sistemini etkiler ve oligospermi, sperm yapısında anormallik, testiküler steroidegenezde bozukluklar, testiküler atrofi, uterus boyutlarında artış ve erken ergenlikten sorumlu olabilir. Bu derlemede endokrin çevre bozuculara maruziyeti ve onların ergenlik üzerine etkilerini değerlendirmeyi amaçladık.

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Cite This Article

ÇETİNKAYA, S. (2009). Endocrine disruptors and their effects on puberty. Dicle Tıp Dergisi, Cilt: 36 - Sayı: 1, 59–66. https://ajindex.com/articles/349270

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