Journals / Dicle Tıp Dergisi / 2021 / Cilt: 48 - Sayı: 3

The Effects of Lactate And Lactate Clearance On Mortality of Stroke Cases Who Admitted To Emergency Department

Acil Servise Başvuran İnme Olgularında Laktat ve Laktat Klirensinin Mortalite Üzerine Etkileri

Pages
577–582
DOI
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⚡ TL;DR(Too Long; Didn't Read)

When evaluated according to the lactate levels and lactate clearance of our surviving and deceased patients, the lactate level at the 24th hour is significantly higher in our patients who died Conclusion: It was revealed that lactate clearance is not a good marker for determining prognosis in patients admitted to the emergency service with a pre-diagnosis of stroke, and the 24th hour lactate level is more significant.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Ischemic and hemorrhagic cerebrovascular diseases are an important cause of morbidity and mortality.
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Key Findings & Data:Methods: Approximately 300 patients were retrospectively analyzed who applied to the Dicle University emergency service with a pre-diagnosis of stroke between 01.01.2018 and 31.12.2018.
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Conclusion & Impact:When evaluated according to the lactate levels and lactate clearance of our surviving and deceased patients, the lactate level at the 24th hour is significantly higher in our patients who died Conclusion: It was revealed that lactate clearance is not a good marker for determining prognosis in patients admitted to the emergency service with a pre-diagnosis of stroke, and the 24th hour lactate level is more significant.
🔬Design:Research Article
📍Scope:2018 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: Ischemic and hemorrhagic cerebrovascular diseases are an important cause of morbidity and mortality. Lactate clearance has been shown to be associated with all mortalities in the critically ill group. In this study, we aimed to investigate the role of lactate and lactate clearance in determining the prognosis in patients with pre-diagnosis of stroke who may be in the critically ill group. Methods: Approximately 300 patients were retrospectively analyzed who applied to the Dicle University emergency service with a pre-diagnosis of stroke between 01.01.2018 and 31.12.2018. The lactate level at the time of admission, lactate level at the 24th hour and lactate clearance at the 24th hour of the 50 patients who met the study criteria were evaluated. The effects of the results on mortality were examined. Results: 50 patients were included in the study. 23 of these patients were men and 27 were women. The mean age of the patients was calculated as 64.18 ± 17.80 years. 6 of the patients who died were male and 13 were female, and the mean age was 66.11 ± 19.95 years. When evaluated according to the lactate levels and lactate clearance of our surviving and deceased patients, the lactate level at the 24th hour is significantly higher in our patients who died Conclusion: It was revealed that lactate clearance is not a good marker for determining prognosis in patients admitted to the emergency service with a pre-diagnosis of stroke, and the 24th hour lactate level is more significant.

Özet

Amaç: İskemik ve hemorajik serebrovasküler hastalıklar, önemli bir morbidite ve mortalite nedenidir. Laktat klirensinin kritik hasta grubunda tüm mortaliteler ile ilişkili olduğu gösterilmiş. Biz bu çalışmada kritik hasta grubu içinde olabilecekinme ön tanılı hastalarda laktat ve laktat klirensinin prognozu tayin etmede yerini araştırmayı amaçladık.Yöntemler: 01.01.2018-31.12.2018 tarihleri arasında Dicle Üniversitesi acil servisine inme ön tanısıyla başvuran yaklaşık 300 hasta retrospektif olarak incelendi. Çalışma kriterlerine uyan 50 hastanın geliş anı laktat değeri, 24. saat laktat değeri ve 24. saat laktat klirensi değerlerine bakıldı. Çıkan sonuçların mortalite üzerine etkileri incelendi.Bulgular: Çalışmaya 50 hasta dahil edildi. Bu hastaların 23’ü erkek, 27’si kadındı. Hastaların yaş ortalaması 64,18±17.80 yıl olarak hesaplandı. Ölen hastaların 6’sı erkek, 13’ü kadın olup yaş ortalaması 66.11±19.95 yıl idi. Sağ kalan ve ölen hastalarımızın laktat düzeyleri ve laktat klirenslerine göre değerlendirildiğinde ölen hastalarımızda 24’üncü saatteki laktat düzeyi anlamlı derecede yüksektirSonuç: İnme ön tanısıyla acile başvuran hastalarda laktat klirensinin prognoz tayini açısından iyi bir marker olamayacağı, 24. Saat laktat değerinin daha anlamlı olduğu ortaya çıktı.

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Cite This Article

ORAK, M., İPEK, M., ÜSTÜNDAĞ, M., YAMAN, M., ALUÇLU, M. U., GÜLOĞLU, C. (2021). The Effects of Lactate And Lactate Clearance On Mortality of Stroke Cases Who Admitted To Emergency Department. Dicle Tıp Dergisi, Cilt: 48 - Sayı: 3, 577–582. https://ajindex.com/articles/348749

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References (14)

  1. Silvestrelli G, Paciaroni M, Caso V, et al. Risk Factors and Stroke Subtypes: Results of Five Consecutive Years of the Perugia Stroke Registry. Clin Exp Hypertens. 2006 Jan 3;28
  2. WHO MONICA Project Principal Invest. The world health organization monica project (monitoring trends and determinants in cardiovascular disease): A major international collaboration. J Clin Epidemiol. 1988;41
  3. Öztürk ZE, İntrakranial İnme Sonrası Saptanan Risk Faktörlerinin Morbidite ve Mortalite Üzerine Etkisi. [Uzmanlık Tezi] İstanbul: Dr. Lütfi Kırdar Kartal Eğitim ve Araştırma Hastanesi Nöroloji Kliniği; 2004
  4. Demirci Şahin A, Üstü Y, Işık D. Serebrovasküler Hastalıklarda Önlenebilen Risk Faktörlerinin Yönetimi. Ankara Med J. 2015 Apr 28;15
  5. Gürger M, Bozdemir MN, Yıldız M, et al. Acil Servise İskemik İnme Nedeniyle Başvuran Hastalarda Hastane İçi Mortalitenin Belirlenmesinde Kardiyak Belirteçlerin Rolü. Turk J Emerg Med 2008; 8: 59-66 6. Demirci Şahin A, Üstü Y, Işık D, Uğurlu M. Serebrovasküler Hastalık Geçiren Hastaların Demografik Özellikleri ve Birinci Basamak Sağlık Merkezlerinde Önlenebilen Risk Faktörlerinin Yönetimi. Ankara Med J. 2015 Nov 24; 15
  6. Levy B. Lactate and shock state: the metabolic view. Curr Opin Crit Care. 2006 Aug; 12
  7. Sargin G, Yavasoglu I, Kadikoylu G, Bolaman Z. Lactic Acidosis: A Short Review of Cases. Dahili ve Cerrahi Bilim Yoğun Bakım Dergisi/ Turkish J Med Surg Intensive Care. 2011 Dec 1; 2
  8. Jones AE. Lactate Clearance in the Acutely Traumatized Patient. Anesthesiology. 2012 Dec 1; 117
  9. Jones AE. Lactate Clearance vs Central Venous Oxygen Saturation as Goals of Early Sepsis Therapy A Randomized Clinical Trial JAMA. 2010 Feb 24; 303
  10. Horn T, Klein J. Neuroprotective effects of lactate in brain ischemia: Dependence on anesthetic drugs. Neurochem Int. 2013 Feb; 62
  11. Zhang Z, Xu X. Lactate Clearance Is a Useful Biomarker for the Prediction of All-Cause Mortality in Critically Ill Patients. Crit Care Med. 2014 Sep; 42
  12. Zhou B-C, Zhang Z, Zhu J-J, Liu L-J, Liu C-F. Blood Lactate or Lactate Clearance: Which Is Robust to Predict the Neurological Outcomes after Cardiac Arrest? A Systematic Review and Meta-Analysis. Biomed Res Int. 2018 Oct 2; 2018
  13. Montiel-Jarquín Á, Láscarez-Lagunas I, SánchezGasca C, et al. Lactate Clearance is a Prognostic Factor in Patients on Shock State. Electron J Gen Med. 2012 Apr 10; 9
  14. Çağlayan T, Özakın E, Özdemir A, et al. Hemorajik Ve İskemik Serebrovasküler Hastalık Tanısı Ala