Journals / Çocuk Enfeksiyon Dergisi / 2009 / Cilt: 3 - Sayı: 4

Neonatal sepsis

Yenidoğan sepsisi

Pages
174–181
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This article reviews the classification, pathogenesis, etiology, epidemiology, clinical findings of neonatal sepsis and current knowledge regarding the diagnosis and treatment of neonatal sepsis.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Sepsis is a significant cause of mortality and morbidity in newborn infants.
📊
Key Findings & Data:Depending on the timing of symptoms and signs, sepsis during the neonatal period classically is divided into early-onset sepsis and late-onset sepsis.
💡
Conclusion & Impact:This article reviews the classification, pathogenesis, etiology, epidemiology, clinical findings of neonatal sepsis and current knowledge regarding the diagnosis and treatment of neonatal sepsis.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Sepsis is a significant cause of mortality and morbidity in newborn infants. Depending on the timing of symptoms and signs, sepsis during the neonatal period classically is divided into early-onset sepsis and late-onset sepsis. Primary risk factors for early-onset sepsis are prematurity, low birth weight, prolonged rupture of membranes, chorioamnionitis, and maternal colonization with group B streptococcus. In late-onset sepsis, maternal obstetric complications are rare and the main risk factors for sepsis are the procedures carried out in hospital to keep the infant alive. This article reviews the classification, pathogenesis, etiology, epidemiology, clinical findings of neonatal sepsis and current knowledge regarding the diagnosis and treatment of neonatal sepsis.

Özet

Sepsis yenidoğan bebeklerde önemli bir mortalite ve morbidite nedenidir. Klasik olarak bulguların ortaya çıkış zamanına göre yenidoğan döneminde görülen sepsis, erken başlangıçlı sepsis ve geç başlangıçlı sepsis olarak ikiye ayrılır. Erken sepsis için başlıca risk faktörleri prematürelik, düşük doğum ağırlığı, erken membran rüptürü, korioamnionit ve doğum kanalının B grubu streptokoklar ile kolonizasyonudur. Geç sepsiste maternal obstetrik komplikasyonlar nadirdir ve sepsis için esas risk faktörleri bebekleri yaşatmak için hastanede yapılan işlemlerdir. Bu makalede yenidoğan sepsisinin klasifikasyonu, patogenezi, etiyolojisi, epidemiyolojisi, klinik bulguları ve tanı ve tedavisindeki güncel bilgiler gözden geçirilmiştir.

🔖

Cite This Article

CENGİZ, A. B. (2009). Neonatal sepsis. Çocuk Enfeksiyon Dergisi, Cilt: 3 - Sayı: 4, 174–181. https://ajindex.com/articles/348629

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (16)

  1. Edwards MS, Baker CJ. Sepsis in the newborn. In: Gershon AA, Hotez PJ, Katz SL (eds): Krugman's Infectious Diseases of Children. 11th ed. Philadelphia: Mosby; 2004. p. 545-61
  2. Saez-Llorens X, McCracken GH. Perinatal bacterial diseases. In: Feigin RD, Cherry JD, Demmler GJ, et al (eds): Textbook of Pediatric Infectious Diseases. 5th ed. Vol
  3. Philadelphia: Saunders; 2004. p. 929-66
  4. Chiesa C, Panero A, Osborn JF, et al. Diagnosis of neonatal sepsis: a clinical and laboratory challenge. Clin Chem 2004; 50: 279-87
  5. Haque KN. Definitions of bloodstream infection in the newborn. Pediatr Crit Care Med 2005; 6 (3 Suppl): 45-9
  6. Schrag S, Schuchat A. Prevention of neonatal sepsis. Clin Perinatol 2005; 32: 601-15
  7. Polin RA, Parravicini E, Regan JA, Taeusch HW. Bacterial sepsis and meningitis. In: Taeusch HW, Ballard RA, Gleason CA (eds). Avery's Diseases of the Newborn. 8th ed. Philadelphia: Elsevier Inc.; 2005. p. 551-77
  8. Stoll BJ. Infections of the neonatal infant. In: Behrman RE, Kliegman RM, Jenson HB (eds): Nelson Textbook of Pediatrics. 17th ed. Philadelphia: Saunders; 2004. p. 623-40
  9. Zaidi AK, Thaver D, Ali SA, Khan TA. Pathogens associated with sepsis in newborns and young infants in developing countries. Pediatr Infect Dis J 2009; 28 (1 Suppl): 10-8
  10. Gerdes JS. Diagnosis and management of bacterial infections in the neonate. Pediatr Clin N Am 2004; 51: 939-59
  11. Weisman LE. Coagulase-negative staphylococcal disease: emerging therapies for the neonatal and pediatric patient. Curr Opin Infect Dis 2004; 17: 237-41
  12. Stoll BJ, Hansen NI, Higgins RD, et al. Very low birth weight preterm infants with early onset neonatal sepsis: the predominance of gram-negative infections continues in the National Institute of Child Health and Human Development Neonatal Research Network, 2002-2003. Pediatr Infect Dis J 2005; 24: 635-9
  13. Makhoul IR, Sujov P, Smolkin T, Lusky A, Reichman B, Israel Neonatal Network. Pathogen-specific early mortality in very low birth weight infants with late-onset sepsis: a national survey. Clin Infect Dis 2005; 40: 218-24
  14. Bizzarro MJ, Raskind C, Baltimore RS, Gallagher PG. Seventy-five years of neonatal sepsis at Yale: 1928-2003. Pediatrics 2005; 116: 595-602
  15. Osrin D, Vergnano S, Costello A. Serious bacterial infections in newborn infants in developing countries. Curr Opin Infect Dis 2004; 17: 217-24
  16. Thaver D, Zaidi AK. Burden of neonatal infections in developing countries: a review of evidence