AI Summary & Key Takeaways
AI InsightNAC is one of thevaluable multimodal treatment options, enables surgery in locally invasive UTUC and contributes positively to survival rate.
📌 3 Key Takeaways
Özet
Upper tract urothelial carcinoma (UTUC) is less common than bladder cancer, but its incidence is increasing. Neoadjuvant chemotherapy (NAC) hasbeen the treatment focus for locally invasive and high-grade UTUC. Herein, we aimed to present a case of a locally advanced non-metastatic UTUC,which was thought to be unresectable due to local invasion, but surgically treated successfully after NAC. A 64-year-old male patient was admittedto another hospital because of right flank pain, which was not accompanied by macroscopic haematuria. He did not have comorbidities in hisanamnesis, but he had a history of smoking 40 packs/year. A locally invasive right kidney tumour was detected in cross-sectional imaging performedat another hospital. He underwent surgery in that hospital, but radical nephroureterectomy could not be performed because of local invasion. Hepresented to our urology department. He was subsequently started with cisplatin-based NAC, which led to the resolution of local invasion. AfterNAC, right radical nephroureterectomy and ipsilateral bladder cuff excision with subcostal and Gibson incisions were performed. No signs of massinvasion or lymph node involvement were detected intraoperatively. He was examined 3 months after surgery. On cystourethroscopy, the bladderwas normal and cytology was benign. No recurrence or metastasis was detected on the whole-body computed tomography. NAC is one of thevaluable multimodal treatment options, enables surgery in locally invasive UTUC and contributes positively to survival rate.