Journals / Kulak Burun Boğaz Uygulamaları / 2017 / Cilt: 5 - Sayı: 1

The treatment results of patients with lower lip cancer and the relationship of tumor size and depth with neck metastasis

Alt dudak kanserli hastalardaki tedavi sonuçları ile tümörün boyutu ve derinliğiyle boyun metastazı arasındaki ilişki

Pages
18–22
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Therefore, we suggest tumor size and depth have a vital role in deciding neck dissection in lower lip cancers.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objectives: This study aims to evaluate the treatment results and the relationship of tumor size and depth with neck metastasis in patients who were operated for lower lip cancer.Patients and Methods: Thirty-five patients (31 males, 4 females; mean age 58.2 years; range 31 to 81 years), who were operated in our clinic due to lower lip cancer between January 2009 and January 2016, were included in this study.
📊
Key Findings & Data:Twenty millimeter for tumor size and 0.6 mm for depth were taken as the limit values during the evaluation of the relationship of tumor size and depth with neck metastasis.
💡
Conclusion & Impact:Therefore, we suggest tumor size and depth have a vital role in deciding neck dissection in lower lip cancers.
🔬Design:Research Article
📍Scope:2009 Verileri
⚙️Variables:Domain Parameters

Abstract

Objectives: This study aims to evaluate the treatment results and the relationship of tumor size and depth with neck metastasis in patients who were operated for lower lip cancer.Patients and Methods: Thirty-five patients (31 males, 4 females; mean age 58.2 years; range 31 to 81 years), who were operated in our clinic due to lower lip cancer between January 2009 and January 2016, were included in this study. The demographic features, examination and clinical findings, performed surgical treatment techniques and histopathological diagnostic results of the patients were evaluated retrospectively. Twenty millimeter for tumor size and 0.6 mm for depth were taken as the limit values during the evaluation of the relationship of tumor size and depth with neck metastasis. P value below 0.05 (p<0.05) was taken as significant in the statistical analysis.Results: We identified cervical neck metastasis in seven and postoperative recurrences in five patients. In addition, three of them died during the follow-up period. One of the 20 patients with tumor size <=20 mm had neck metastasis. However, six of the 15 patients with a tumor size >20 mm had neck metastasis. One of the 19 patients with tumor depth <=0.6 mm had neck metastasis. However, six of the 16 patients with tumor depth >0.6 mm had neck metastasis. In statistical analysis, we found that both the tumor size and depth significantly increases the risk of neck metastasis (p<0.05).Conclusion: Increase in tumor size as well as tumor depth increases the risk of neck metastasis. Therefore, we suggest tumor size and depth have a vital role in deciding neck dissection in lower lip cancers.

Özet

Amaç: Bu çalışmada alt dudak kanseri nedeniyle cerrahi tedavi uyguladığımız hastaların tedavi sonuçları ve tümöre ait faktörler ile boyun metastazı ve tümör nüksü arasındaki ilişki incelendi.Hastalar ve Yöntemler: Çalışmaya, Ocak 2009 - Ocak 2016 tarihleri arasında kliniğimizde alt dudak kanseri nedeniyle cerrahi uygulanan 35 hasta (31 erkek, 4 kadın; ort. yaş 58.2 yıl; dağılım 31-81 yıl) dahil edildi. Hastaların demografik özellikleri, muayene ve klinik bulguları, uygulanan cerrahi tedavi yöntemleri, histopatolojik tanı sonuçları geriye dönük olarak değerlendirildi. Tümör boyutu ve derinliği ile boyun metastazı ve tümör nüksü arasındaki ilişki incelenirken sınır değer olarak tümör boyutu 20 mm, derinliği ise 0.6 mm alındı. İstatistiksel analizde p 20 mm olan 15 hastanın altısında boyun metastazı vardı. Tümör derinliği 0.6 mm olan 16 hastanın altısında boyun metastazı vardı. Yapılan istatistiksel analizde hem tümör derinliğinin hem de tümör boyutunun boyun metastaz riskini anlamlı oranda artırdığı bulundu (p<0.05).Sonuç: Tümörün boyutunun yanında derinliğinin artışı da boyun metastazı olasılığını artırmaktadır. Bu nedenle tümörün boyutu ve derinliğinin, boyun diseksiyonuna karar vermede belirleyici rol oynayabileceğini düşünmekteyiz.

🔖

Cite This Article

ŞENGÜL, E., ÖZBAY, M., YILMAZ, B., TOPÇU, İ. (2017). The treatment results of patients with lower lip cancer and the relationship of tumor size and depth with neck metastasis. Kulak Burun Boğaz Uygulamaları, Cilt: 5 - Sayı: 1, 18–22. https://ajindex.com/articles/343468

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (14)

  1. Politi M, Salgarelli A, Panziera G, Cortelazzi R. Surgical treatment of neoplasms of the lip. Minerva Chir 1993
  2. [Abstract] 2. Czerninski R, Zini A, Sgan-Cohen HD. Lip cancer: incidence, trends, histology and survival: 1970-2006. Br J Dermatol 2010
  3. Perea-Milla López E, Miñarro-Del Moral RM, MartínezGarcía C, Zanetti R, Rosso S, Serrano S, et al. Lifestyles, environmental and phenotypic factors associated with lip cancer: a case-control study in southern Spain. Br J Cancer 2003
  4. Moretti A, Vitullo F, Augurio A, Pacella A, Croce A. Surgical management of lip cancer. Acta Otorhinolaryngol Ital 2011
  5. Luna-Ortiz K, Güemes-Meza A, Villavicencio-Valencia V, Mosqueda-Taylor A. Upper lip malignant neoplasms. A study of 59 cases. Med Oral Patol Oral Cir Bucal 2012
  6. Hakulinen T, Tryggvadóttir L, Gislum M, Storm HH, Bray F, Klint A, et al. Trends in the survival of patients diagnosed with cancers of the lip, oral cavity, and pharynx in the Nordic countries 1964-2003 followed up to the end of 2006. Acta Oncol 2010
  7. Rodolico V, Daniele E, Leonardi V, Marra G, Luciani A, Settineri G, et al. Node status in lower lip squamous cell carcinoma in relation to tumor size, histological variables and DNA ploidy. Anticancer Res 1998
  8. Thompson AK, Kelley BF, Prokop LJ, Murad MH, Baum CL. Risk Factors for Cutaneous Squamous Cell Carcinoma Recurrence, Metastasis, and Disease-Specific Death: A Systematic Review and Meta-analysis. JAMA Dermatol 2016
  9. Sollamo EM, Ilmonen SK, Virolainen MS, Suominen SH. Sentinel lymph node biopsy in cN0 squamous cell carcinoma of the lip: A retrospective study. Head Neck 2016
  10. Edge SB, Compton CC. The American Joint Committee on Cancer: the 7th edition of the AJCC cancer staging manual and the future of TNM. Ann Surg Oncol 2010
  11. Salgarelli AC, Sartorelli F, Cangiano A, Pagani R, Collini M. Surgical treatment of lip cancer: our experience with 106 cases. J Oral Maxillofac Surg 2009
  12. Gooris PJ, Vermey A, de Visscher JG, Burlage FR, Roodenburg JL. Supraomohyoid neck dissection in the management of cervical lymph node metastases of squamous cell carcinoma of the lower lip. Head Neck 2002
  13. Bhandari K, Wang DC, Li SC, Jiang BH, Guo YX, Koirala U, et al. Primary cN0 lip squamous cell carcinoma and elective neck dissection: Systematic review and metaanalysis. Head Neck 2015
  14. Shah JP. Patter