Journals / Zeynep Kamil Tıp Bülteni / 2020 / Cilt: 51 - Sayı: 3

Practices in Pancreatic Neoplastic Cystic Tumors - A Training and Research Hospital Experience

Pankreasın Neoplastik Kistik Tümörlerinde Pratikler - Bir Eğitim veAraştırma Hastanesi Deneyimi

Pages
133–136
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Further investigations should be done with MR-MRCP and EUS (including fluid and cell aspirate exa-minations) as they may have malignant potential; The diagno-sis, follow-up and surgical decision should be made according to the AGA 2015 guideline due to its appropriate and practical guidance.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: Neoplastic cystic tumors of the pancreas are mostly incidentally detected and they carry risk of malignancy.
📊
Key Findings & Data:We ai-med to reveal practical points of the management according to 2015 guideline of the American Gastroenterology Association.Material and Methods: Twenty-five patients with pancreatic neoplastic cystic tumors were retrospectively analyzed.
💡
Conclusion & Impact:Further investigations should be done with MR-MRCP and EUS (including fluid and cell aspirate exa-minations) as they may have malignant potential; The diagno-sis, follow-up and surgical decision should be made according to the AGA 2015 guideline due to its appropriate and practical guidance.
🔬Design:Research Article
📍Scope:2015 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: Neoplastic cystic tumors of the pancreas are mostly incidentally detected and they carry risk of malignancy. We ai-med to reveal practical points of the management according to 2015 guideline of the American Gastroenterology Association.Material and Methods: Twenty-five patients with pancreatic neoplastic cystic tumors were retrospectively analyzed. Pa-tients' ages, genders, whether they were incidental or sympto-matic when they received their initial pre-diagnosis with USG, CT, MR (+/- MRCP) or other guiding factors and EUS findings (amylase, CEA, CA 19-9 in the aspiration fluid and cell as-piration results) were evaluated. MR-MRCP and EUSs of all patients were completed. The follow-up and surgery of the pa-tients were evaluated.Results: Of the 25 patients, 18 (72%) were female and 7 (28%) were male. The average age was 57.3 and ranged from 30-77. Ten (40%) patients with serous cystic tumor, 6 (24%) with mu-cinous cystic tumor, 8 (32%) with intraductal papillary muci-nous tumor, and 1 (4%) with solid pseudopapillary tumor were evaluated. MR-MRCP and EUS findings were compatible and complementary in diagnosis. Pathology results of 7 (28%) ope-rated patients were compatible and 1 (4%) patient had invasive cancer.Conclusion: Neoplastic cystic tumors of the pancreas are most-ly detected incidentally. Further investigations should be done with MR-MRCP and EUS (including fluid and cell aspirate exa-minations) as they may have malignant potential; The diagno-sis, follow-up and surgical decision should be made according to the AGA 2015 guideline due to its appropriate and practical guidance.

Özet

Amaç: Çoğunlukla insidental olarak rastlanan ve malign olma ihtimalinden dolayı pankreasın neoplastik kistik lezyonlarının, Amerikan Gastroenteroloji Derneğinin 2015 kılavuzu örnekli-ğinde, pratik noktalarını ortaya koymayı amaçladık .Gereçler ve Yöntem: Pankreas neoplastik kistik tümörlü 25 hasta retrospektif olarak incelendi. Hastaların yaşları, cinsi-yetleri, ilk ön tanılarını aldıklarında insidental mi semptomatik mi olduğu, ilk yönlendirici radyolojik tetkikikin USG, BT, MR (+/- MRCP) veya diğer yönlendirici faktörler ve takiplerinde EUS bulguları (aspirasyon sıvısında amilaz, CEA, CA 19-9, ince iğne hücre aspirasyon sonuçları) değerlendirildi. Tüm hastaların yönlendirme sonrası eksikleri giderilerek MR-MR-CP ve EUS’ları tamamlandı. Hastaların takip ve cerrahisi de-ğerlendirildi.Bulgular: 25 hastanın 18 (%72)’si kadın, 7 (%28)’i erkekti. Ortalama yaş 57,3 olup 30-77 aralığında değişmekteydi. Se-röz kistik tümörlü 10 (%40), Müsinöz kistik tümörlü 6 (%24), intraduktal papiller müsinöz tümörlü 8 (%32), solid psödopa-piller tümörlü 1 (%4) hasta değerlendirildi. MR-MRCP ve EUS bulguları tanı koymada uyumlu ve tamamlayıcıydı. Ameliyat edilen 7 (%28) hastanın patoloji sonuçları uyumlu olup 1 (%4) hastada invaziv kanser tesbit edildi.Sonuç: Pankreasın neoplastik kistik tümörleri çoğunlukla in-sidental olarak tesbit edilir. Malign potansiyel taşıyabilece-ğinden dolayı ileri tetkikler MR-MRCP ve EUS (sıvı ve hücre aspiratı incelemeleri dahil) ile yapılmalı; tanı, takip ve cerrahi kararı uygun ve pratik yönlendirmeleri nedeniyle AGA 2015 kı-lavuzuna göre verilmelidir.

🔖

Cite This Article

ÇAKIR, M., AKTÜRK, O. M. (2020). Practices in Pancreatic Neoplastic Cystic Tumors - A Training and Research Hospital Experience. Zeynep Kamil Tıp Bülteni, Cilt: 51 - Sayı: 3, 133–136. https://ajindex.com/articles/335127

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (1)

  1. Megibow AJ, Baker ME, Gore RM, Taylor A. The inci-dental pancreatic cyst. Radiol Clin North Am. 2011;49:349–359. DOI: 10.1016/j.rcl.2010.10.008 2- Lee KS, Sekhar A, Rofsky NM, Pedrosa I. Prevalence of incidental pancreatic cysts in the adult population on MR imaging. Am J Gastroenterol. 2010;105:2079–2084. DOI: 10.1038/ajg.2010.122 3- Scheiman JM, Hwang JH, Moayyedi P. American gast-roenterological association technical review on the diagnosis and management of asymptomatic neoplastic pancreatic cysts. Gastroenterology. 2015;148:824–848.e22. 4- Zamboni G, Kloeppel G, Hruban RH, Klöppel G. Muci-nous cystic neoplasms of the pancreas. In: Aaltonen LA, Ha-milton SR, editors. World health organization classification of tumours. Pathology and genetics of tumours of the digestive system. Lyon, France: IARC Press; 2000. p. 234. 5- Santhi Swaroop Vege, Barry Ziring, Rajeev Jain, Paul Moayyedi, and the Clinical Guidelines Committee. American Gastroenterological Association Institute Guideline on the Di-agnosis and Management of Asymptomatic Neoplastic Pancre-atic Cysts. Gastroenterology 2015;148:819–822. 6- Nakai Y, Isayama H, Itoi T, et al. Role of endoscopic ultrasonography in pancreatic cystic neoplasms: where do we stand and where will we go? Dig Endosc. 2014;26 (2):135-43. doi.org/10.1111/den.12202 7- Brugge WR, Lewandrowski K, Lee-Lewandrowski E, et al. Diagnosis of pancreatic cystic neoplasms: a report of the cooperative pancreatic cyst study. Gastroenterology. 2004;126 (5):1330-6. DOI: 10.1053/j.gastro.2004.02.013 8- Springer S, Wang Y, Dal Molin M, et al. A combination of molecular markers and clinical features improve the classifica-tion of pancreatic cysts. Gastroenterology. 2015;149 (6):1501-10. doi: 10.1053/j.gastro.2015.07.041. 9- Bick BL, Enders FT, Levy MJ, et al. The string sign for diagnosis of mucinous pancreatic cysts. Endoscopy. 2015;47:626–631. doi: 10.1055/s-0034-1391484 10- Raquel Herranz Pérez, Felipe de la Morena López, Ce-cilio SantanderVaquero. Diagnostic Approach to Cystic Panc-reatic Neoplasms. Rev Col Gastroenterol vol.34 no.1 Bogotá, 2019. 11- Yunus Yavuz, Rıfat Yalın. Pankreasın kistik tümörleri: Ayırıcı tanının önemi. Turkish Journal of Surgery yayınları, Ankara, 2020. 12- Austin L Chiang and Linda S Lee. Clinical approach to incidental pancreatic cysts. World J Gastroenterol. 2016; 22 (3): 1236–1245. doi: 10.3748/wjg.v22.i3.1236 13- Basar O, Brugge WR. Pancreatic cyst guidelines: Which one to live by? Gastrointest Endosc. 2017;8