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Journals / Van Tıp Dergisi / 2016 / Cilt: 23 - Sayı: 1

A comparison on the Intrauterine Insemination Outcomes of Infertile Women Undergoing Ovulation Induction with Clomiphene Citrate and rFSH

İnfertil Kadınlarda Klomifen Sitrat ve rFSH ile Ovülasyon İndüksiyonu Sonrası İntrauterin İnseminasyon Sonuçlarının Karşılaştırılması

Muhammet YILDIZ
Numan ÇİM
Erkan ELÇİ
Recep YILDIZHAN
Pages
81–85
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

No difference was found in the pregnancy rates in women with a periovulatory endometrium thickness of <7 mm

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The aim of this study was to investigate the effect of recombinant follicle stimulating hormone (rFSH) and clomiphene used for ovulation induction in patients undergoing intrauterine insemination (IUI) treatment on pregnancy rates.
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Key Findings & Data:Materials and Methods: The retrospective study included 102 menstrual cycles in which IUI treatment was performed.
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Conclusion & Impact:No difference was found in the pregnancy rates in women with a periovulatory endometrium thickness of <7 mm
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: The aim of this study was to investigate the effect of recombinant follicle stimulating hormone (rFSH) and clomiphene used for ovulation induction in patients undergoing intrauterine insemination (IUI) treatment on pregnancy rates. Materials and Methods: The retrospective study included 102 menstrual cycles in which IUI treatment was performed. To achieve ovulation induction, clomiphene citrate and rFSH were administered in two distinct groups. The two groups were compared in terms of demographic characteristics, diagnosis, and treatment outcomes. Results: The two groups had similar pregnancy rates. In the clomiphene citrate group, periovulatory endometrium was thinner than 7 mm. The correlation between periovulatory endometrium thickness and pregnancy rate was similar in both groups. Conclusion: Application of clomiphene citrate and rFSH led to similar pregnancy rates in women undergoing IUI treatment. No difference was found in the pregnancy rates in women with a periovulatory endometrium thickness of <7 mm

Özet

Amaç: İntrauterin inseminasyon (IUI) yapılan hastalarda ovülasyon indüksiyonu amacıyla kullanılan rFSH ile klomifen sitrat'ın gebelik oranlarına etkisinin araştırılması amaçlandı. Gereç ve Yöntem: IUI yapılan 102 siklus retrospektif olarak değerlendirildi. Ovülasyon indüksiyonu amacıyla komifen sitrat ve rFSH kullanılan iki gruptaki kadınların demografik özellikleri, tanıları ve tedavi sonuçları karşılaştırıldı. Bulgular: Her iki grupta benzer gebelik oranları tespit edildi. Klomifen sitrat grubunda periovulatuar endometrium 7 mm'den daha inceydi. İki grupta da, periovulatuar endometrium kalınlığı ile gebelik oranları ilişkisi benzerdi. Sonuç: Klomifen sitrat veya rFSH kullanımıyla birlikte IUI uygulanan kadınlarda gebelik oranları benzerdir. Preovülatuar endometrium kalınlığının 7 mm'den ince olan kadınlarda gebelik oranları değişmemektedir

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Cite This Article

YILDIZ, M., ÇİM, N., ELÇİ, E., YILDIZHAN, R. (2016). A comparison on the Intrauterine Insemination Outcomes of Infertile Women Undergoing Ovulation Induction with Clomiphene Citrate and rFSH. Van Tıp Dergisi, Cilt: 23 - Sayı: 1, 81–85. https://ajindex.com/articles/334713

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References (8)

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