Journals / Van Tıp Dergisi / 2002 / Cilt: 9 - Sayı: 1

Serum protein levels in healty old seubjects in Van region

Van yöresinde yaşayan sağlıklı yaşlı bireylerde serum protein düzeyleri

Pages
19–23
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

In conclusion total protein levels of healthy elderly in Van region were found in normal range, albumin levels decreased, as globulin levels increased.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:There are some biochemical and physiological changes inold population.
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Key Findings & Data:In this study serum levels of total protein and electrophoretical fractions of 165 healthy elderly persons with different social economic levels and nutrition habits living in Van region were analysed.
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Conclusion & Impact:In conclusion total protein levels of healthy elderly in Van region were found in normal range, albumin levels decreased, as globulin levels increased.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Yaşlanma · Elektroforez · Sağlık durumu

Abstract

There are some biochemical and physiological changes inold population. In this study serum levels of total protein and electrophoretical fractions of 165 healthy elderly persons with different social economic levels and nutrition habits living in Van region were analysed. Also a control group composed of 25 healthy adults aged between 20 and 45 participated. In the elderly group, mean total protein, albumin and globulin levels were 7,35±0,8 (g/dl), 3,6±0,53 (g/dl) and 3,75±0,60 (g/dl), respectively. Total protein and albumin levels of elderly compared with the control group were lower, but only albumin levels were statistically significantly (p<0,05). Electrophoreticaly, whilst serum albumin levels were significantly lower (p<0.01), alpha-1 and gamma globulin levels were higher (p<0.05). In conclusion total protein levels of healthy elderly in Van region were found in normal range, albumin levels decreased, as globulin levels increased.

Özet

Yaşlanma sürecinde bir çok biyokimyasal ve fizyolojik değişiklikler meydana gelir. Bu çalışmada Van merkez ve çevre yerleşim birimlerinde yaşayan sağlıklı yaşlılarda serum total protein düzeyleri ve bunların elektroforetik fraksiyonlarının serum düzeylerinin araştırılması amaçlandı.Bu çalışmaya merkez ve çevre yerleşim birimlerinde yaşayan yaşları 50-85 (ortalama yaş 63± 7 yıl) arasında olan sağlıklı 165 yaşlı birey alındı. Kontrol grubunu ise yaşları 20-40 (ortalama yaş 32±8 yıl) arasında olan 25 sağlıklı yetişkin bireyler oluşturdu. Yaşlı grupta ortalama total protein 7,3±0,8 (g/dl), albumin 3,6±0,53 (g/dl) ve globulin 3,75±0,60 (g/di) olarak bulundu. Total protein ve albumin düzeyleri yaşlılarda kontrol grubuna oranla düşük bulundu, fakat sadece albumin düşüklüğü istatistiksel olarak anlamlıydı (p<0.05). Elektroforetik olarak da serum albumin düzeyleri anlamlı olarak düşük (p<0.01) ve alfa-1 globulin ve gama-globulin düzeyleri anlamlı olarak yüksekti (p<0.05).Van ve çevresinde yaşayan sağlıklı yaşlılarda total protein düzeyleri normal sınırlar içinde bulunmakla birlikte, yaşlanmaya bağlı olarak albumin düzeylerinin azaldığı ve globulin düzeylerinin ise arttığı gözlenmiştir.

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Cite This Article

TARAKÇIOĞLU, M., DİLEK, İ., ŞEKEROĞLU, M. R., DÜLGER, H., ERKOÇ, R., AKSOY, H., AVCI, E. (2002). Serum protein levels in healty old seubjects in Van region. Van Tıp Dergisi, Cilt: 9 - Sayı: 1, 19–23. https://ajindex.com/articles/334638

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References (20)

  1. Liew CC: Biochemical aspects of aging. In Gornal A 6,ed. Aplied biochemistry of clinical disorders.2nd ed. Philadelphia; Lippincott-Raven:55S-565,1986
  2. Brass IB: The biology and physiology of aging. West JMed.153:641-645, 1990
  3. Knight JA: Laboratory issues regarding geriatric patients. Lab. Med. 28(7):458-461, 1997
  4. Strehler BL: A critique of theories biological aging. In Dietz AA, ed. Aging; its chemistry. Washington, DC; American Association of clinical chemistry:25-45,1980
  5. Gorman LS: Aging: laboratory testing and theories. Clin Lab Sci. 8:24-30,1995
  6. Charlock DM, Laude-Flaws M: Stress, immune Function and the older adult. Med Lab Observer. 29(4):48-54, 1997
  7. Miller SM: Antioxidants and aging. Med Lab Observer. 29:42-51,1997
  8. Emyre-Zacher P, Isabel SM: The impact of an aging population on the clinical laboratory. Med Lab Observer. 29(4):48-54,1997
  9. Young DS: Effects of preanalytical variables on clinical laboratory tests.I51 ed. Washington.DC AACC. Press.:19-39,1993
  10. Sasse EA: The determination of reference intervals. In Faulkner.WR and Metes S. Geriatric clinical chemistry: Reference values. Washington, DC. AACC Press:6-17,1994
  11. Garry PJ: Nutrition and aging. In Faulkner. WR and Metes S, eds. Geriatric clinical chemistry: Reference values. Washington, DC. AACC Press;48-72,1994
  12. Reaven GM, Chen N, Hollenbeck C, Chen YD: Effect of age on glucose tolerance and glucose tolerance and glucose uptake in healthy individuals. J Am Geriatr 43:69-78,1988
  13. Michael CB, Janet LB, Edwards P.F: Clinical chemistry. Lippincott Wİllİams-Wİlkİns. 2000,pp:572-582
  14. Shauna CA, Susan C: Clinical Chemistry: Concepts and Applications. W.B. Saunders Company, Philadelphia.: 675-686,1993
  15. Tİetz NW, Shaey OF, Welcstein DR: Laboratory values in fit aging individuals; sexagenarians through centenarians. In Faulkner. WR and Meites S, eds. Geriatric clinical chemistry: reference values. Washington, DC. AACC Press:145-184,1994
  16. Rochman H: Clinical Pathology in the Elderly Basel,Karger,1988,pp 38-49
  17. Knight JA: Laboratory medicine and the aging process. Chicago: American Society of Clinical Pathologists, 1996
  18. Tİmiras PS: Aging of gastrointestinal tract and liver. In Timiras PS, ed. Physiological basis of aging and geriatrics. 2nd ed. Boca Raton FL: CRCPress,:247-257,1994
  19. Annesley T: Pharmacokinetic changes in the elderly. Clin Lab Sci 3:100-102,1990
  20. Shamburek RD, Farrar JT: Disorders of the digestive system in th