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Journals / Üroonkoloji Bülteni / 2019 / Cilt: 18 - Sayı: 1

Comparison of Lidocaine and Prilocaine Efficiencies in Periprostatic Nerve Block for Transrectal Prostate Biopsy: A Randomized Prospective Study

GÖKHAN SÖNMEZ
Numan BAYDİLLİ
ŞEVKET TOLGA TOMBUL
Gülen GÜLER
Abdullah DEMİRTAŞ
Pages
1–5
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Therefore, prilocaine is a preferable agent for prostate biopsy under TRUS guidance.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Periprostatic nerve block (PPNB) and intrarectal local anesthesia (IRLA) are two of the most commonly used methods for pain control in the transrectal ultrasonography (TRUS)-guided prostate needle biopsy procedure, which is the standard method for the diagnosis of prostate cancer.
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Key Findings & Data:Materials and Methods: A total of 64 patients with suspicious rectal examination symptoms and/or serum prostate-specific antigen (PSA) elevation underwent standard 12-core TRUS-guided prostate needle biopsy.
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Conclusion & Impact:Therefore, prilocaine is a preferable agent for prostate biopsy under TRUS guidance.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

Objective: Periprostatic nerve block (PPNB) and intrarectal local anesthesia (IRLA) are two of the most commonly used methods for pain control in the transrectal ultrasonography (TRUS)-guided prostate needle biopsy procedure, which is the standard method for the diagnosis of prostate cancer. This study compared the efficacy of IRLA alone and with PPNB using lidocaine or prilocaine. Materials and Methods: A total of 64 patients with suspicious rectal examination symptoms and/or serum prostate-specific antigen (PSA) elevation underwent standard 12-core TRUS-guided prostate needle biopsy. The patients were divided into 3 groups: IRLA with lidocaine gel only (group 1), IRLA with lidocaine gel plus PPSB with 2% lidocaine injection (group 2), and IRLA with lidocaine gel plus PPSB with 2% prilocaine injection (group 3). Patients’ pain levels were assessed by visual analog scale (VAS) immediately (VAS-1) and at 45 minutes (VAS-2) after prostate biopsy. In addition, serum PSA levels, age, body mass index (BMI), prostate volume, and cancer detection rates of the patients were recorded. Results: There were no statistical differences between the groups in terms of total PSA, age, BMI, prostate volume, or cancer detection rates. According to VAS-1 score, group 1 had more severe pain compared to the other groups, while there was no significant difference between groups 2 and 3. When VAS-2 score was examined, group 1 experienced the most severe pain, while group 3 was the least painful group. When asked which biopsy step was the most painful, all groups reported that introduction of ultrasound probe into the rectum was the most painful. Conclusion: The combination of IRLA and PPNB seems to be a more effective method than IRLA alone for pain control during TRUS-guided prostate biopsy. Prilocaine and lidocaine have comparable onset but the effect of prilocaine lasts longer. Therefore, prilocaine is a preferable agent for prostate biopsy under TRUS guidance.

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Cite This Article

SÖNMEZ, G., BAYDİLLİ, N., TOMBUL, Ş. T., GÜLER, G., DEMİRTAŞ, A. (2019). Comparison of Lidocaine and Prilocaine Efficiencies in Periprostatic Nerve Block for Transrectal Prostate Biopsy: A Randomized Prospective Study. Üroonkoloji Bülteni, Cilt: 18 - Sayı: 1, 1–5. https://ajindex.com/articles/334379

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