Journals / Viral Hepatitis Journal / 2015 / Cilt: 21 - Sayı: 1

Zonguldak İlinde Üniversite Hastanesine Başvuran Gebelerde HBsAg, Anti-HBs ve Anti-HCV Seropozitiflik Oranları

HBsAg, Anti-HBs and Anti-HCV Seropositivity Rates among Pregnant Women Attending a University Hospital in Zonguldak

Pages
31–34
DOI
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⚡ TL;DR(Too Long; Didn't Read)

Conclusion: While similar rates of seroprevalence for HBsAg and anti-HCV were found as compared to the previous reports from Turkey, anti-HBs positivity rates were lower than that in most of the previous reports.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: To explore the HBV and HCV seroprevalence rates among pregnant women attending the Obstetric Outpatient Unit at the Medical Faculty of Zonguldak Bülent Ecevit University and to provide contributory data to the already existing data from the other geographical regions of Turkey.
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Key Findings & Data:Materials and Methods: HBsAg, anti-HBs and anti-HCV seropositivity rates were retrospectively investigated among a total of 1084 pregnant women attending the Obstetric Outpatient Unit at the Medical Faculty of Zonguldak Bülent Ecevit University between January 2012 and January 2014 Serum assays were performed using a chemiluminescence immunoassay method according the manufacturer’s instructions (Cobas e 411 Analyzer, Roche Diagnostics, Mannheim, Germany).
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Conclusion & Impact:Conclusion: While similar rates of seroprevalence for HBsAg and anti-HCV were found as compared to the previous reports from Turkey, anti-HBs positivity rates were lower than that in most of the previous reports.
🔬Design:Research Article
📍Scope:2012 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: To explore the HBV and HCV seroprevalence rates among pregnant women attending the Obstetric Outpatient Unit at the Medical Faculty of Zonguldak Bülent Ecevit University and to provide contributory data to the already existing data from the other geographical regions of Turkey. Materials and Methods: HBsAg, anti-HBs and anti-HCV seropositivity rates were retrospectively investigated among a total of 1084 pregnant women attending the Obstetric Outpatient Unit at the Medical Faculty of Zonguldak Bülent Ecevit University between January 2012 and January 2014 Serum assays were performed using a chemiluminescence immunoassay method according the manufacturer’s instructions (Cobas e 411 Analyzer, Roche Diagnostics, Mannheim, Germany). Statistical analyses of the study data were performed using SPSS 18.0 software package (SPSS Inc., Chicago IL, USA). Results: The mean age of the 1084 pregnant participants was 29.12±5.48 years (min: 17, max: 46 y) and the average gestational age was 10.7±4.64 weeks. HBsAg, anti-HBs, and anti-HCV detection rates were 4% (n=43), 7.3% (n=79), and 0.6% (n=7), respectively. With regard to age groups, HBsAg was positive in 3.1%, 3.7%, 4.4%, and 5.9% of the women who were below 20 years of age, between 21 and 30 years of age, between 31 and 40 years of age, and over 40 years of age, respectively. Conclusion: While similar rates of seroprevalence for HBsAg and anti-HCV were found as compared to the previous reports from Turkey, anti-HBs positivity rates were lower than that in most of the previous reports.

Özet

Amaç: Bu çalışmada, Zonguldak Bülent Ecevit Üniversitesi Tıp Fakültesi Hastanesi, kadın Hastalıkları ve Doğum kliniğine başvuran gebelerde HBV ve HCV seroprevalans oranlarının araştırılması ve elde edilen oranların ülkemizin farklı yerlerindeki oranlarla karşılaştırılarak ülkemiz verilerine katkı sağlanması amaçlanmıştır. Gereç ve Yöntemler: Bülent Ecevit Üniversitesi Tıp Fakültesi kadın Hastalıkları Doğum kliniğine Ocak 2012-Ocak 2014 tarihleri arasında başvuran 1800 gebenin HBsAg, anti-HBs ve anti-HCV seropozitiflik oranları retrosektif olarak incelenmiştir. Verileri yeterli olan 1084 gebe çalışmaya dahil edilmiştir. Hastaların serumları kemilümünesans immünassay yöntemi ile üretici firmanın (Cobas e 411 Analyzer, Roche Diagnostics, Mannheim, Germany) önerilerine göre çalışılmıştır. Elde edilen veriler SPSS 18.0 (SPSS Inc., Chicago IL, USA) paket programı kullanılarak istatiksel değerlendirilmesi yapılmıştır. Bulgular: Çalışmaya alınan 1084 gebenin yaş ortalaması 29,12±5,48 (min: 17, max: 46), ortalama gebelik haftası 10,7±4,64 idi. HBsAg pozitifliği %4 (n=43), anti-HBs %7,3 (n=79), anti-HCV %0,6 (n=7) oranında bulunmuştur. HBsAg pozitifliği 20 yaş altında %3,1, 21-30 yaş arası %3,7, 31-40 yaş arası %4,4, 40 yaş üstü ise %5,9 olarak saptandı. Sonuç: Sonuç olarak çalışmamızda HBsAg ve anti-HCV seroprevalansı ülkemizde yapılan diğer çalışmalarla benzer oranda bulunurken, anti- HBs pozitifliği ise bazı çalışmalar ile benzer sonuçlarda olsada, birçok çalışmaya göre düşük oranda saptanmıştır.

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Cite This Article

AYNİOĞLU, A., AYNIOĞLU, Ö., AKAR, T., AYDIN, M., ALTUNOK, E. S. (2015). Zonguldak İlinde Üniversite Hastanesine Başvuran Gebelerde HBsAg, Anti-HBs ve Anti-HCV Seropozitiflik Oranları. Viral Hepatitis Journal, Cilt: 21 - Sayı: 1, 31–34. https://ajindex.com/articles/332702

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References (18)

  1. Thomas D, Zoulim F. New challenges in viral hepatitis. Gut. 2012;61(1):1-5
  2. World Health Organisation 2012. Prevention&Control of Viral Hepatitis Infection. Framework for Global Action.2012
  3. Ott JJ, Stevens GA, Groeger J, Wiersma ST. Global epidemiology of hepatitis B virusinfection: newestimates of age specific HBsAg seroprevalence and endemicity. Vaccine. 2012;30(12):2212-2219
  4. Cicek ÇA, Duygu F ve İnakçı İH. Şanlıurfa İlinde kadın Hastalıkları ve Doğum Hastanesine Başvuran kadınlarda Hepatit B ve Hepatit C Seroprevalansı: Üç- Yıllık Değerlendirme. Viral Hepatitis Journal. 2012;18(1):15-18
  5. Petrova M, kamburov V. Breastfeeding and chronic HBV infection:Clinical and social implications. World J Gastroenterol. 2010;16:5042-5046
  6. Shepart CW, Finelli L, Alter J. Global Epidemiyology of Hepatitis C Virus İnfection. Lancet İnfect Dis. 2005;5;558-567
  7. Hupertz VF, Wyllie R. Perinatal hepatitis C infection. Pediatr Infect Dis J. 2003;22:369-372
  8. Prasad MR, Honegger JR. Hepatitis C virus in pregnancy. American journal of perinatology. 2013;30(2):149-159
  9. Pipili C, Cholongitas E. Μanagement of patients with hepatitis B and C before and after liver and kidney transplantation. World J Hepatol. 2014;6(5):315-325
  10. Mıstık R. Türkiye’de viral hepatit epidemiyolojisi. Tabak F, Balık İ, Tekeli E (eds). Viral Hepatit 2007
  11. Baskı. İstanbul: Viral Hepatitle Savaşım Derneği, 2007:10-50
  12. Tosun S. Türkiye’de viral hepatit B Epidemiyolojisi-Yayınların Metaanalizi. In: Tabak F, Tosun S (eds). Viral Hepatit 2013, 7. Basım. İstanbul: İstanbul Medikal Yayıncılık, İstanbul 2013:25- 81
  13. Hou J, Liu Z, Gu F. Epidemiology and Prevention of Hepatitis B Virus Infection. Int J Med Sci. 2005;2(1):50-57
  14. Murad EA, Babiker SM, Gasim GI, Rayis DA, Adam I. Epidemiology of hepatitis B and hepatitis C virus infections in pregnant women in Sana’a, Yemen. BMC Pregnancy Childbirth. 2013;13:127
  15. Mamadou S, Ide M, Maazou AR, Aoula B, Labo S, Bozari M. HIV infection and hepatitis B seroprevalence among antenatal clinic attendees in Niger, West Africa. HIV AIDS (Auckl). 2012;4:1-4
  16. Obi SN, Onah HE, Ezugwu FO. Risk factors for hepaptitis B infection during pregnancy in a Nigerian obstetric population. Journal of Obstetrics and Gynecology. 2006;26(8):770-772
  17. Mehta kD, Antala S, Mistry M, Goswami Y. Seropositivity of hepatitis B, hepatitis C, syphilis, and HIV in antenatal women in India. J Infect Dev Ctries. 2013;7(11):832-837
  18. Surya GP, kornia