Journals / Viral Hepatitis Journal / 2017 / Cilt: 23 - Sayı: 3

İki Nadir Hepatit Sebebi: Fasioliazis ve Brusellozis

Two Rare Causes of Hepatitis: Fascioliasis and Brucellosis

Pages
76–79
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

To our knowledge, this case is one of the few cases in the literature that showing the co-infection of the liver by both fascioliasis and brucellosis

📌 3 Key Takeaways

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Objective & Hypothesis:Brucellosis and fascioliasis are zoonoses which induce different type of cell-mediated immune responses and rarely cause hepatitis with together.
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Key Findings & Data:Brucellosis induces T helper type 1 (Th1) immune response whereas Fasciola hepatica induces T helper type 2 (Th2) immune.
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Conclusion & Impact:To our knowledge, this case is one of the few cases in the literature that showing the co-infection of the liver by both fascioliasis and brucellosis
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Brucellosis and fascioliasis are zoonoses which induce different type of cell-mediated immune responses and rarely cause hepatitis with together. Brucellosis induces T helper type 1 (Th1) immune response whereas Fasciola hepatica induces T helper type 2 (Th2) immune. It may be speculated that chronic fascioliasis can predispose to brucellosis by suppression of Th1 response against brucellosis. In this paper, we present a patient who was diagnosed with brucellosis as well as chronic fasciolasis on the basis of parasite that was seen incidentally during the abdomen ultrasonography. To our knowledge, this case is one of the few cases in the literature that showing the co-infection of the liver by both fascioliasis and brucellosis

Özet

Brusellozis ve fasioliazis farklı tiplerde hücresel bağışıklık yanıtını uyaran zoonozlar olup birlikte nadiren hepatit tablosuna neden olurlar. Brusellozis, T yardımcı hücre tip 1 (Th1) ile bağışıklık yanıtını uyarırken Fasciola hepatica ise T yardımcı hücre tip 2 (Th2) ile uyarır. Th1 yanıtını baskılaması dolayısıyla kronik fasciola enfeksiyonun brusellozise yatkınlık yarattığı düşünülebilir. Bu yazıda brusellozis tanısına ek olarak batın ultrasonografi ile rastlantısal olarak görülen parazit dolayısıyla kronik fasiolazis tanısı alan bir olgu sunulmaktadır. Literatürde bildiğimiz kadarıyla olgumuz fasiolazis ve brusellozis ile eş zamanlı enfekte olan nadir olgular arasında yer almaktadır

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Cite This Article

ÖNAL, U., YAMAZHAN, T., PULLUKÇU, H., TAŞBAKAN, M., TAMSEL, S., ERDOĞAN, D. D., KORKMAZ, M., SİPAHİ, O. R. (2017). İki Nadir Hepatit Sebebi: Fasioliazis ve Brusellozis. Viral Hepatitis Journal, Cilt: 23 - Sayı: 3, 76–79. https://ajindex.com/articles/332637

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References (14)

  1. Mas-Coma S, Bargues MD, Valero MA. Fascioliasis and other plant-borne trematode zoonoses. Int J Parasitol. 2005;35:1255- 1278
  2. Tasbakan MI, Yamazhan T, Gokengin D, Arda B, Sertpolat M, Ulusoy S, Ertem E, Demir S. Brucellosis: a retrospective evaluation. Trop Doct. 2003;33:151-153
  3. Skendros P, Boura P. Immunity to brucellosis. Rev Sci Tech. 2013;32:137-147
  4. Brady MT, O’Neill SM, Dalton JP, Mills KH. Fasciola hepatica suppresses a protective Th1 response against Bordetella pertussis. Infect Immun. 1999;67:5372-5378
  5. Buzgan T, Karahocagil MK, Irmak H, Baran AI, Karsen H, Evirgen O, Akdeniz H. Clinical manifestations and complications in 1028 cases of brucellosis: a retrospective evaluation and review of the literature. Int J Infect Dis. 2010;14:e469-478
  6. Mas-Coma S, Valero MA, Bargues MD. Chapter 2. Fasciola, lymnaeids and human fascioliasis, with a global overview on disease transmission, epidemiology, evolutionary genetics, molecular epidemiology and control. Adv Parasitol. 2009;69:41- 146
  7. Karahocagil MK, Akdeniz H, Sunnetcioglu M, Cicek M, Mete R, Akman N, Ceylan E, Karsen H, Yapici K. A familial outbreak of fascioliasis in Eastern Anatolia: a report with review of literature. Acta Trop. 2011;118:177-183
  8. Caban-Hernandez K, Gaudier JF, Ruiz-Jimenez C, Espino AM. Development of two antibody detection enzyme-linked immunosorbent assays for serodiagnosis of human chronic fascioliasis. J Clin Microbiol. 2014;52:766-772
  9. Saba R, Korkmaz M, Inan D, Mamikoglu L, Turhan O, Gunseren F, Cevikol C, Kabaalioğlu A. Human fascioliasis. Clin Microbiol Infect. 2004;10:385-387
  10. Palmer D. Detection of Trematode Eggs and Eimeria Leuckarti – Sedimentation Method (Fest) – Faecal Samples2013 04.06.2015 [cited 2015. Available from: https://www.agric.wa.gov.au/sites/ gateway/files/DAFWA%20approved%20fluke%20egg%20 sedimentation%20test%20(FEST).pdf
  11. Mas-Coma MS, Esteban JG, Bargues MD. Epidemiology of human fascioliasis: a review and proposed new classification. Bull World Health Organ. 1999;77:340-346
  12. Sezgin O, Altintas E, Disibeyaz S, Saritas U, Sahin B. Hepatobiliary fascioliasis: clinical and radiologic features and endoscopic management. J Clin Gastroenterol. 2004;38:285-291
  13. Sakru N, Korkmaz M, Demirci M, Kuman A, Ok UZ. Fasciola hepatica infection in echinococcosis suspected cases. Turkiye Parazitol Derg. 2011;35:77-80
  14. Kilimcioglu AA, Girginkardesler N, Korkmaz M, Ozkol M, Duzgun F, Ostan I, Pabuşcu Y, Dinç G, Ok UZ. A mass