Journals / Türk Toraks Dergisi / 2012 / Cilt: 13 - Sayı: 2

Influenza a (H1N1) virus enfeksiyonlu hastaların klinik analizi

Clinical analysis in ınfluenza a (H1N1) virus patients

Pages
45–49
DOI
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Although most Influenza A (H1N1) virus infected patients hospitalized in our clinic had progressed well but pulmonary complications should be considered. (Tur Toraks Der 2012; 13: 45-9)

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The first influenza virus pandemic of the 21st century began in Mexico in 2009 and spread rapidly all over the world.
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Key Findings & Data:We described the clinical and epidemiologic characteristics of the 31 patients admitted to the Deparment of Chest Disease due to influenza A (H1N1) virus infection.
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Conclusion & Impact:Although most Influenza A (H1N1) virus infected patients hospitalized in our clinic had progressed well but pulmonary complications should be considered. (Tur Toraks Der 2012; 13: 45-9)
🔬Design:Research Article
📍Scope:2009 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: The first influenza virus pandemic of the 21st century began in Mexico in 2009 and spread rapidly all over the world. We described the clinical and epidemiologic characteristics of the 31 patients admitted to the Deparment of Chest Disease due to influenza A (H1N1) virus infection. Material and Method: In this study we evaluated 51 patients with high clinical suspicion for Influenza A (H1N1) virus infection. We used real time reverse transcriptase chain reaction test (RT-PCR) test for diagnosis. Thirty-one (15 female, 16 male) of 51 patients RT-PCR test were positive for Influenza A (H1N1) virus infection. Demographic features, clinical and laboratory characteristics of these patients were assessed. Results: The mean age of Influenza A (H1N1) virus infected patients was 40.8±13.1. Cough was the most common symptom (90%) and 11 patients (35%) had pneumonia. Leucopenia (48.3%), C reactive protein elevation (90.3%) and creatine phosphokinase elevation (71%) were notable laboratory findings. T and B lymphocyte subgroups were also evaluated and compared with Turkish adult normals. Lymphocyte subgroups were not different in the patients with influenza A (H1N1) virus statistically. Conclusion: Influenza virus may cause pandemias with different subgroups. Although most Influenza A (H1N1) virus infected patients hospitalized in our clinic had progressed well but pulmonary complications should be considered. (Tur Toraks Der 2012; 13: 45-9)

Özet

Amaç: Yirmibirinci yüzyılın ilk influenza virüs pandemisi Meksika’da başladı ve hızla tüm dünyaya yayıldı. Biz bu çalışmada, göğüs hastalıkları kliniğimizde; influenza A (H1N1) virüsü infeksiyonu ile takip edilen 31 hastanın klinik ve epidemiyolojik özelliklerini tanımlamayı amaçladık. Gereç ve Yöntem: Çalışmaya influenza A (H1N1) virus enfeksiyonu için yüksek klinik şüphesi olan 51 (15-55 yaş) hasta alındı. Influenza A (H1N1) virus enfeksiyonu tanısında gerçek zamanlı revers transkriptaz zincir reaksiyonu (RT-PCR) testi kullanıldı. Çalışmaya alınan 51 hastanın 31’inde (15 kadın, 16 erkek) influenza A (H1N1) virus için RT-PCR testi pozitif bulundu. Bu hastaların demografik verileri, klinik ve laboratuvar özellikleri, tedaviye cevapları değerlendirildi. Bulgular: Influenza A (H1N1) virus enfeksiyonlu hastaların yaş ortalaması 40.8±13.1 idi. En sık semptom öksürük (%90) iken, 11(%35) hastada pnömoni geliştiği görüldü. Lökopeni (%48.3), C reaktif protein (%90.3) ve kreatinin fosfokinaz (%71) yüksekliği belirgin laboratuvar bulgular idi. Ayrıca serumda T, B lenfosit alt grupları akım-sitometrik olarak incelenerek normal Türk erişkin değerleri ile karşılaştırıldı. Influenza A (H1N1) virus enfeksiyonun lenfosit alt gruplarında istatistiksel olarak anlamlı bir farklılık yapmadığı görüldü. Sonuç: İnfluenza virus değişik alt tipleri ile pandemilere yol açabilen bir virüstür. Kliniğimizde takip edilen influenza A (H1N1) virus enfeksiyonlu hastaların prognozlarının kötüye gitmemesi yüz güldürücüdür ancak yine de pulmoner komplikasyon gibi sistemik etkileri gözardı edilmemelidir. (Tur Toraks Der 2012; 13: 45-9)

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Cite This Article

DURU, S., KÖKER, M. Y., UYANUSTA, Ç., ŞENCAN, N., ALTAŞ, B., ALBAYRAK, N., ARDIÇ, S. (2012). Influenza a (H1N1) virus enfeksiyonlu hastaların klinik analizi. Türk Toraks Dergisi, Cilt: 13 - Sayı: 2, 45–49. https://ajindex.com/articles/329629

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