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Journals / Türk Toraks Dergisi / 2011 / Cilt: 12 - Sayı: 1

Akciğerin kaviter lezyonlarında kolonize olan funguslar - Klinikopatolojik bir çalışma

Colonizing fungi in cavitary lesions of lung – A clinicopathological study

Sundaram CHALLA
Shantveer UPPIN
Swetha HANUMANTHU
Tara Roshni PAUL
Lakshmi VEMU
Manmadh Rao TALLURI
Dharam Rakshak AYAPATI
Ramesh Chandra MISHRA
Ravinutala Venkata Mishra4 KUMAR
Pages
19–26
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Hence an attempt at identification of the colonizing fungus either with morphological or cultural evidence should be done.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Patients with preexisting lung cavities are prone to develop fungal masses inside the cavity.
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Key Findings & Data:Material and Method: Retrospective study carried out in a tertiary care hospital from 1993 to 2008.
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Conclusion & Impact:Hence an attempt at identification of the colonizing fungus either with morphological or cultural evidence should be done.
🔬Design:Review & Systematic Survey
📍Scope:2008 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: Patients with preexisting lung cavities are prone to develop fungal masses inside the cavity. Though Aspergillus sp. is the most common fungus colonizing these cavities other fungi may rarely show colonization. Material and Method: Retrospective study carried out in a tertiary care hospital from 1993 to 2008. All patients diagnosed with a fungal ball on chest radiographs/CT chest with subsequent histological confirmation were analysed. Demographic data, clinical, radiological and surgical findings were retrieved from the medical records. Histopathology slides were reviewed along with special stains for fungi. Fungi were identified on morphology and/or culture. Results: There were 25 patients in the study period with 20 males and 5 females. A past history of tuberculosis was present in 17 patients. The colonizing fungi were identified as Aspergillus sp. in 20, dematiaceous fungi in 3 and mixed infection (Aspergillus sp. and Candida sp.) in 2. Culture confirmation was available in five specimens, which showed Aspergillus fumigatus in 2, Aspergillus flavus 1, Pseudallescheria boydii 1 and Candida albicans (in mixed infection) in 1. Conclusion: Fungi other than Aspergillus sp. can colonize pulmonary cavities. Hence an attempt at identification of the colonizing fungus either with morphological or cultural evidence should be done.

Özet

Amaç: Akciğer kavitesi mevcut olan hastalar kavite içinde fungal kitle oluşmasına yatkındır. Aspergillus sp. bu kaviteleri kolonize eden en yaygın fungus olmakla birlikte, ender olarak diğer funguslar kolonizasyon gösterebilir. Gereç ve Yöntem: Üçüncü basamak bir hastanede 1993’ten 2008’e retrospektif bir çalışma gerçekleştirildi. Göğüs radyografisi/ CT’sinde mantar topu gözlenen ve daha sonra histolojik olarak doğrulanan bütün hastalar analiz edildi. Demografik veriler, klinik, radyolojik ve cerrahi bulgular tıbbi kayıtlardan elde edildi. Histopatoloji slaytları funguslar için özel boyalarla değerlendirildi. Funguslar morfoloji ve/ veya kültüre dayalı olarak tanımlandı. Bulgular: Çalışma döneminde 20 erkek ve 5 kadın olmak üzere 25 hasta mevcuttu, 17 hastada geçmişte tüberküloz öyküsü vardı. Kolonize eden mantar 20 hastada Aspergillus sp. olarak, 3 hastada dematiasöz fungus olarak ve 2 hastada karışık enfeksiyon (Aspergillus sp. ve Candida sp.) olarak tanımlandı. Kültür doğrulaması beş örnekte sağlanabildi; bunlar 2 hastada Aspergillus fumigatus, 1 hastada Aspergillus flavus, 1 hastada Pseudallescheria boydii ve 1 hastada Candida albicans (karışık enfeksiyonda). Sonuç: Aspergillus sp. dışındaki funguslar pulmoner kaviteleri kolonize edebilir. Bu nedenle kolonize eden mantarın morfoloji veya kültürle tanımlanması için çaba gösterilmelidir.

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Cite This Article

CHALLA, S., UPPIN, S., HANUMANTHU, S., PAUL, T. R., VEMU, L., TALLURI, M. R., AYAPATI, D. R., MISHRA, R. C., KUMAR, R. V. M. (2011). Akciğerin kaviter lezyonlarında kolonize olan funguslar - Klinikopatolojik bir çalışma. Türk Toraks Dergisi, Cilt: 12 - Sayı: 1, 19–26. https://ajindex.com/articles/329625

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References (18)

  1. Woods GL, Schnadig VJ, Walker DH, Winn WC, Jr. Infectious disease pathology: Clinical cases. New Delhi: Butterworth Heinemann; 2000; 56-7
  2. Akbari JG, Varma PK, Neema PK et al. Clinical profile and surgical outcome for pulmonary aspergilloma: a single center experience. Ann Thorac Surg 2005; 80: 1067-72
  3. Kathuria SK, Rippon J. Non-aspergillus aspergillomas. Am J Clin Pathol 1982; 78: 870-3
  4. Lahiri TK, Agarwal D, Reddy GE, Bajoria A. Pulmonary mucoraceous ball. Indian J Dis Allied Sci 2001; 43: 107-10
  5. Tojima H, Tokudome T, Otsuka T. Chronic pulmonary mucormycosis that developed in preexisting cavities caused by tuberculosis in a patient with diabetes mellitus and liver cirrhosis. Nihon Kyobu Shikkan Gakkai Zasshi 1997; 35: 100-5
  6. Raminez J, Byrd RP Jr, Roy TM. Chronic cavitary pulmonary sporotrichosis: efficacy of oral itraconazole. J Ky Med Assoc 1998: 96: 103-5
  7. Al Refai M, Duhamel C, Le Rochais JP, Icard P. Lung Scedosporiosis: a differential diagnosis of aspergillosis. Eur J Cardiothorac Surg 2002; 21: 938-9
  8. Domej W, Hermann J, Krause R et al. Lung cavities, mycetomas and hemoptysis. Wien Med Wochenschr 2007; 157: 466-72
  9. Lam SM, Lan AC, Ma MW, Yam LY. Pseudallescheria boydii or Aspergillus fumigatus in a lady with an unresolving lung infiltrate, and a literature review. Respirology 2008; 13: 478-80
  10. Pratap H, Dewan RK, Singh L, Gill S, Vaddadi S. Surgical treatment of pulmonary aspergillomas: a series of 72 cases. Indian J chest Dis Allied Sci 2007; 49: 23-7
  11. Shah R, Vaideeswar P, Pandit SP. Pathology of pulmonary aspergillomas. Ind J Pathol Microbiol 2008;51:342-5
  12. Regnard JF, Icard P, Nicolosi M et al. Aspergilloma: a series of 89 surgical cases. Ann Thorac Surg 2000; 69: 898-903
  13. Caidi M, Kabiri H, Al Aziz S et al. Surgical treatment of pulmonary aspergillomas. 278 cases. Presse Med 2006; 35: 1819-24
  14. Brik A, Salem AM, Kamal AR et al. Surgical outcome of pulmonary aspergillomas. Eur J Cardiothorac Surg; 2008; 34: 882-5
  15. Okubo K, Kobayashi M, Morikawa H et al. Favorable acute and long-term outcomes after the resection of pulmonary aspergillomas. Thorac Cardiovasc Surg 2007; 55: 108-11
  16. Kleinschmidt-DeMasters BK. Central nervous system Aspergillosis: A 20 year retrospective series. Hum Pathol 2002; 33: 116-24
  17. Pasqualotto AC, Denning DW. An aspergillomas caused by Aspergillus flavus. Med Mycol 2008; 46: 275-8
  18. Awaya Y, Nagao Y, Murakami I, Shigetou E, Okimasa S, Shibata S. Case of pulmona