Journals / Türk Toraks Dergisi / 2009 / Cilt: 10 - Sayı: 4

A case with lymhoepithelioma-like carcinoma situated in the lung

Akciğer yerleşimli lenfoepitelyoma benzeri karsinomlu bir olgu

Pages
201–203
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The overall survival is more favourable in Lymhoepithelioma-like carcinoma compared with non-small cell lung cancinoma.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Lymhoepithelioma-like carcinoma is a rare form of lung cancer.
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Key Findings & Data:Epstein-Barr virus infection has a basic role in the tumourogenesis of the Lymhoepithelioma-like carcinoma.
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Conclusion & Impact:The overall survival is more favourable in Lymhoepithelioma-like carcinoma compared with non-small cell lung cancinoma.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Akciğer neoplazmları · Herpesvirüs 4 · insan

Abstract

Lymhoepithelioma-like carcinoma is a rare form of lung cancer. Epstein-Barr virus infection has a basic role in the tumourogenesis of the Lymhoepithelioma-like carcinoma. Although it is strongly associated with Epstein-Barr virus infection in Asian patients, there is controversy over whether an association exists in patients from Western counties. The curative surgical resection is adequate for early-stage disease but for the metastatic disease the choice of treatment is chemotherapy. The overall survival is more favourable in Lymhoepithelioma-like carcinoma compared with non-small cell lung cancinoma. Curative surgical resection was performed in the patient who was asyptomatic and had an incidentally discovered solitary pulmonary nodule on chest roentgenogram. The positron emission tomography finding especially suggested malignancy. Histopathologically, it was reported as Lymhoepithelioma-like carcinoma and previous exposure to Epstein-Barr virus was documented with IgG antibody test, which is not very specific. Our case was presented with literature findings.

Özet

Lenfoepitelyoma benzeri karsinoma akciğer kanserlerinin ender görülen bir formudur. Lenfoepitelyoma benzeri karsinoma tümör genezisinde Epstein-Barr virus enfeksiyonunun temel rol oynadığı düşünülmektedir. Asyalı hastalarda Epstein-Barr virus enfeksiyonu ile güçlü ilişkisi gösterilmesine rağmen, batılı ülkelerden olan hastalarda bu ilişkinin gösterilememesi çelişkili bir durum oluşturmaktadır. Erken evre hastalıkta küratif cerrahi rezeksiyon yeterli iken, metastatik hastalıkta tedavi seçeneği kemoterapidir. Küçük hücreli dışı akciğer kanseri ile karşılaştırıldığında Lenfoepitelyoma benzeri karsinomada survi daha iyidir. Asemptomatik ve akciğer grafisinde tesadüfen saptanan bir soliter pulmoner nodül olan olguya yapılan incelemeler, özellikle pozitron emisyon tomografisinin maligniteyi desteklemesi üzerine küratif cerrahi rezeksiyon uygulandı. Histopatolojik incelemesi lenfoepitelyoma benzeri karsinoma olarak raporlanan hastanın Epstein-Barr virus maruziyetini belirlemek için spesifik olmamakla birlikte yapılan EBV IgG sonucu pozitif olarak bulundu. Olgumuz literatür bilgileri eşliğinde sunulmuştur.

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Cite This Article

GÖZÜBÜYÜK, A., KAVAKLI, K., ÇAYLAK, H., GENÇ, O. (2009). A case with lymhoepithelioma-like carcinoma situated in the lung. Türk Toraks Dergisi, Cilt: 10 - Sayı: 4, 201–203. https://ajindex.com/articles/329581

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References (9)

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