Journals / Türk Üroloji Dergisi/Turkish Journal of Urology / 2008 / Cilt: 34 - Sayı: 3

Current situation of antibiotic resistance against common pathogens in urology clinics

Üroloji kliniklerinde görülen patojenlere karşı antimikrobiyal direncin güncel durumu

Pages
363–367
DOI
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AI Summary & Key Takeaways

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Conclusion: According to us, resistance to the antibiotics frequently used for ampiric treatment of UTI was found to be higher than expected, For this reason every doctor should follow the advances closely to keep their knowledge about bacterial susceptibility and treatment cost fresh and should use latest information while choosing antimicrobial agents and should know the local flora of the region that he works.

📌 3 Key Takeaways

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Objective & Hypothesis:Introduction: Urinary tract infections are one of the most common problems encountered in urology clinics.
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Key Findings & Data:Materials and Methods: 969 urine cultures sent from inpatient urology clinics and 9078 cultures sent from outpatient urology clinics between 2004 and 2005 were retrospectively evaluated.
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Conclusion & Impact:Conclusion: According to us, resistance to the antibiotics frequently used for ampiric treatment of UTI was found to be higher than expected, For this reason every doctor should follow the advances closely to keep their knowledge about bacterial susceptibility and treatment cost fresh and should use latest information while choosing antimicrobial agents and should know the local flora of the region that he works.
🔬Design:Research Article
📍Scope:2004 Verileri
⚙️Variables:İlaç direnci · mikrobiyal · Kültür ortamı

Abstract

Introduction: Urinary tract infections are one of the most common problems encountered in urology clinics. Antibiotic resistance varies in time, and misuse of antibiotics enhances this process. Knowledge of antimicrobial resistance patterns of potential strains and causative pathogens may facilitate the appropriate treatment choice. Materials and Methods: 969 urine cultures sent from inpatient urology clinics and 9078 cultures sent from outpatient urology clinics between 2004 and 2005 were retrospectively evaluated. In addition, resistance rates for each pathogen were analyzed. Results: Pathogens were isolated in 253 of 969 (26%) urine cultures sent from inpatient clinics and 982 of 9078 (10.8%) urine cultures sent from outpatient clinics. 49% of pathogens isolated from the cultures of inpatient clinics were E.coli, 4% were Pseudomonas aeruginosa and 13% were Staphylococcus aureus. Pathogens isolated from the cultures of outpatient clinics were E.Coli (61%), Pseudomonas aeruginosa (4%), and Staphylococcus aureus (13%). Resistance to ciprofloxacin, the most widely used antibiotic of urology practice, was 70% in inpatient clinics and 38% in outpatient clinics. This incidence was 46% and 18% for gentamycin, 61% and 23% for cefuroxime, 31% and 18% for nitrofurantoin, 66% and 55% for trimethoprim-sulphamethoxazole. Conclusion: According to us, resistance to the antibiotics frequently used for ampiric treatment of UTI was found to be higher than expected, For this reason every doctor should follow the advances closely to keep their knowledge about bacterial susceptibility and treatment cost fresh and should use latest information while choosing antimicrobial agents and should know the local flora of the region that he works.

Özet

Üriner sistem enfeksiyonları üroloji klinik ve polikliniklerinde tedavi gerektiren en sık sorunlardan biridir. Antibiyotik direnci zaman içinde değişmekte, özellikle de antibiyotiklerin yanlış kullanımı bu değişikliği hızlandırmaktadır. Ampirik tedavi gerektiğinde potansiyel suşların ve etken patojenlerin antibiyotik dirençlerinin bilinmesi doğru tedavi seçimini kolaylaştıracaktır. 2004 ve 2005 yıllarında üroloji kliniğinde yatan hastalardan gönderilmiş 969 idrar kültürü ve üroloji polikliniğinden gönderilmiş toplam 9078 idrar kültürü retrospektif olarak değerlendirildi. Yatan hastalardan gönderilen 969 idrar kültürünün 253’ünde (%26), ve poliklinik hastalarından gönderilen 9078 örneğin 982’sinde (%10.8) üreme oldu. Yatan hastalarda üreyen patojenlerin %49’u E.coli, %15’i pseudomonas aeruginosa ve %6’sı staphylococcus aureus idi. Poliklinik hastalarında üreyen patojenler ise sırasıyla %61 E.coli, %4 pseudomonas aeruginosa ve %13 staphylococcus aureus olarak izole edildi. Üroloji pratiğinde en çok kullanılan antibiyotiklerinden biri olan siprofloksasine yatan hastalarda %70, poliklinik hastalarında ise %38 oranında direnç tespit edildi. Bu oran gentamisin için %46 ve %18, sefuroksim için %61 ve %23, nitrofurantoin için %31 ve %18, trimethoprim-sulfamethoksazol için %66 ve %55 olarak tespit edildi. Üriner sistem enfeksiyonlarının ampirik tedavisi için oldukça sık kullanılan antibiyotiklere karşı direnç, beklenilenden daha yüksek oranda çıkmıştır. Bu nedenle her hekimin bakterilerin duyarlılık ve tedavi maliyetleri ile ilgili bilgilerini taze tutmak üzere gelişmeleri yakından takip etmesi, antimikrobiyal ajan seçerken en yeni bilgileri kullanması ve çalıştığı bölgenin lokal florasını bilmesi gerekmektedir.

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Cite This Article

ÖZTÜRK, M. İ., KOCA, O., KALKAN, S., KAYA, C., KARAMAN, M. İ. (2008). Current situation of antibiotic resistance against common pathogens in urology clinics. Türk Üroloji Dergisi/Turkish Journal of Urology, Cilt: 34 - Sayı: 3, 363–367. https://ajindex.com/articles/328726

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