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Journals / Türk Üroloji Dergisi/Turkish Journal of Urology / 2007 / Cilt: 33 - Sayı: 4

Antibiotic prophylaxis in transrectal ultrasound guided prostate biopsy: Comparison of two different antibiotic schemes

Transrektal ultrason eşliğinde prostat biyopsisinde antibiyotik profilaksisi: İki farklı antibiyotik uygulamasının karşılaştırılması

Sakıp ERTURHAN
İlker SEÇKİNER
Faruk YAĞCI
Ahmet ERBAĞCI
MEHMET SOLAKHAN
Mehmet ÇELİK
Pages
487–490
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: On the light of our findings, ceftriaxone plus ornidazole scheme is more effective in prevention of infectious complications after prostate biopsy when compared to ciprofloxacin plus ornidazole scheme.

📌 3 Key Takeaways

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Objective & Hypothesis:Introduction: The aim of this study was to evaluate the efficacy of two different prophylactic schemes for prevention to infectious complications after transrectal prostate biopsy.
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Key Findings & Data:Materials and Methods: Between September 2004 and December 2006, a total of 244 patients, who underwent prostate biopsy due to elevated PSA and/or suspicious finding in rectal examination, were included in this study.
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Conclusion & Impact:Conclusion: On the light of our findings, ceftriaxone plus ornidazole scheme is more effective in prevention of infectious complications after prostate biopsy when compared to ciprofloxacin plus ornidazole scheme.
🔬Design:Research Article
📍Scope:2004 Verileri
⚙️Variables:Anti-bakteriyel ajanlar · Biyopsi · Ornidazol

Abstract

Introduction: The aim of this study was to evaluate the efficacy of two different prophylactic schemes for prevention to infectious complications after transrectal prostate biopsy. Materials and Methods: Between September 2004 and December 2006, a total of 244 patients, who underwent prostate biopsy due to elevated PSA and/or suspicious finding in rectal examination, were included in this study. While ciprofloxacin plus ornidazole was given in the first 104 patients (Group 1); ceftriaxone plus ornidazole were given in the remaining 140 patients (Group 2) for prophylaxis. Results: A total of 19 infectious complications were found (14 in group 1 and 5 in group 2). Number of infectious complications in group 1 was found higher than group 2 (p=0.02). However, there was no statistically significant difference found between two groups in other complications (p>0.05). Conclusion: On the light of our findings, ceftriaxone plus ornidazole scheme is more effective in prevention of infectious complications after prostate biopsy when compared to ciprofloxacin plus ornidazole scheme.

Özet

Bu çalışmada, transrektal prostat biyopsisi sonrası infeksiyöz istenmeyen yan etkilerin önlenmesinde kullanılan iki farklı antibiyotik uygulamasının etkinliğinin araştırılması amaçlanmıştır. Eylül 2004 Aralık 2006 tarihleri arasında, yüksek PSA ve/veya şüpheli rektal inceleme bulgusu nedeniyle prostat biyopsisi alınan toplam 240 hasta çalışmaya alındı. Profilaksi için ilk 104 hastada siprofloksasin+ornidazol verilirken, kalan 140 hastada seftriakson+ornidazol uygulandı. Toplam 19 infeksiyöz istenmeyen yan etki bulundu (14 grup 1, 5 grup 2). Grup 1’deki infeksiyöz istenmeyen yan etkilerin sayısı grup 2’den yüksek olmuştur (p=0.02). Buna karşın iki grup arasında diğer istenmeyen yan etkiler açısından anlamlı farklılık bulunmamıştır (p>0.05). Elde ettiğimiz bulgular ışığında, seftriakson+ornidazol rejimi siprofloksasin+ornidazol rejimi ile karşılaştırıldığında, prostat biyopsisi sonrası infeksiyöz istenmeyen yan etkileri önlemede daha etkilidir.

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Cite This Article

ERTURHAN, S., SEÇKİNER, İ., YAĞCI, F., ERBAĞCI, A., SOLAKHAN, M., ÇELİK, M. (2007). Antibiotic prophylaxis in transrectal ultrasound guided prostate biopsy: Comparison of two different antibiotic schemes. Türk Üroloji Dergisi/Turkish Journal of Urology, Cilt: 33 - Sayı: 4, 487–490. https://ajindex.com/articles/328335

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