Journals / Türk Üroloji Dergisi/Turkish Journal of Urology / 2007 / Cilt: 33 - Sayı: 1

Metastatic malignant melanoma presenting with hematuria

Hematüri ile ortaya çıkan metastatik malin melanoma

Pages
124–127
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Solitary, depigmented and vegetating lesions at cystoscopy also should keep in mind to be metastatic of malignant melanoma, although most of the case reports described these lesions as dark blue-black, solitary or multiple and nodular or vegetating lesions.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Introduction: We report a rare case of a previously asymptomatic patient presenting with gross hematuria and a bladder mass, which was found to be metastatic melanoma.
📊
Key Findings & Data:After transurethral resection of atypical bladder tumor, pathological findings made us suspected malignant melanoma and radiological findings supported metastatic melanoma.
💡
Conclusion & Impact:Solitary, depigmented and vegetating lesions at cystoscopy also should keep in mind to be metastatic of malignant melanoma, although most of the case reports described these lesions as dark blue-black, solitary or multiple and nodular or vegetating lesions.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Melanom · Orta yaşlı · Ölümle sonuçlanma

Abstract

Introduction: We report a rare case of a previously asymptomatic patient presenting with gross hematuria and a bladder mass, which was found to be metastatic melanoma. After transurethral resection of atypical bladder tumor, pathological findings made us suspected malignant melanoma and radiological findings supported metastatic melanoma. The patient died due to widespread disease and systemic therapy was not helpful. Solitary, depigmented and vegetating lesions at cystoscopy also should keep in mind to be metastatic of malignant melanoma, although most of the case reports described these lesions as dark blue-black, solitary or multiple and nodular or vegetating lesions.

Özet

Olgu bildirimizde daha önceden asemptomatik olan bir hastada şiddetli hematüri ve mesanede kitle ile ortaya çıkan ender görülen bir metastatik melanoma olgusunu sunuyoruz. Transüretral rezeksiyon ile atipik mesane tümörünün çıkarılmasından sonra patolojik bulgular malin melanoma açısından şüphe uyandırdı ve radyolojik bulgular da metastatik malin melanoma olduğunu destekledi. Sistemik terapiden fayda sağlanamadı ve hastalığın yayılımına bağlı hasta kaybedildi. Olgu bildirilerinin çoğunda lezyonlar koyu mavi-siyah renkte, soliter veya mültipl sayıda, nodüler veya vejetatif karakterde tanımlanmakla birlikte sistoskopide görülen soliter, depigmente, vejetatif özellikteki kitlelerin de metastatik malin melanoma olabileceğinin akılda tutulması gerekir.

🔖

Cite This Article

HALEFOĞLU, A. M., ŞEN, E., ATIŞ, R. G., KAHRAMAN, A. D., SAKIZ, D., ERGENEKON, E. (2007). Metastatic malignant melanoma presenting with hematuria. Türk Üroloji Dergisi/Turkish Journal of Urology, Cilt: 33 - Sayı: 1, 124–127. https://ajindex.com/articles/328306

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (13)

  1. Stein BS, Kendall R: Malignant melanoma of the genitourinary tract. J Urol. 132: 859-868, 1984
  2. Menendez Lopez V, Alvarez-Vijande Garcia R, Sole Arques M, et al: Bladder metastasis of malignant melanoma; report of a case. Arch Esp Urol. 55: 1277-9, 2002
  3. Landis SH, Murray T, Bolden S, et al: Cancer statistics, 1999. CA Cancer J Clin. 49: 8-31, 1999
  4. Dahm P, Gschwend JE: Malignant non-ürethelial neoplasm of the urinary bladder; a review. Eur Urol. 44: 672- 681, 2003
  5. Demirkesen O, Yaycioglu O, Uygun N, et al: A case of metastatic malignant melanoma presenting with hematuria. Urol Int. 64: 118-120, 2000
  6. Mohan H, Ahal S, Nada R, et al: Osteosarcoma of the bladder: A case report. Indian J Pathol Microbiol. 44: 451-452, 2001
  7. Feldman PA, Madeb R, Naroditsky I, et al: Metastatic breast cancer to the bladder: A diagnostic challenge and review of the literature. Urology; 59: 138, 2002
  8. Cormier JN, Abati A, Fetsch P, et al: Comparative analysis of the in vivo expression of tyrosinase, MART- 1/Melan-A and gap100 in metastatic melanoma lesions: Implications for immunotherapy. J Immunother. 21: 27- 31, 1998
  9. Legha SS, Ring S, Papadopoulos N, et al: A prospective evaluation of a triple-drug regimen containing cisplatin, vinblastine and dacarbazine (CVD) for metastatic melanoma. Cancer; 64: 2024-2029, 1989
  10. Lee CSD, Komenaka IK, Hurst-Wicker KS, et al: Management of metastatic malignant melanoma of the bladder. Urology; 62: 351, 2003
  11. Rosenberg SA, Yang JC, Topalian SL, et al: Treatment of 283 consecutive patients with metastatic melanoma or renal cell cancer using high-dose bolus interleukin-2. JAMA; 271: 907-913, 1994
  12. Dudley ME, Wunderlich JR, Robbins PF, et al: Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes. Science; 298: 850-854, 2002
  13. Minev BR: Melanoma vaccines. Semin Oncol. 29: 479- 493, 2002.