Journals / Uludağ Üniversitesi Veteriner Fakültesi Dergisi / 2003 / Cilt: 22 - Sayı: 1

Efficacy of eqvalan (ivermectin) and equimax (ivermectin+praziquantel) against strongylidae species in naturally infected horses

Eqvalan (İvermectin) ve equimax (ivermectin+praziquantel)'ın doğal efekte atlarda strongylidae türlerine etkileri

Pages
45–49
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It is concluded that treatments of horses either with Eqvalan® or Equimax® for the prevention of strongylosis should be administered with intervals of 7 weeks.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The present study was carried out to determine the efficacy rates and the duration of efficacy of two anthelmintic pastes (Eqvalan® and Equimax®) on horses naturally infected by strongyles.
📊
Key Findings & Data:Twenty horses were divided into two groups each of 10 animals.
💡
Conclusion & Impact:It is concluded that treatments of horses either with Eqvalan® or Equimax® for the prevention of strongylosis should be administered with intervals of 7 weeks.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:yan etkiler · ilaç tedavisi · parasitoz

Abstract

The present study was carried out to determine the efficacy rates and the duration of efficacy of two anthelmintic pastes (Eqvalan® and Equimax®) on horses naturally infected by strongyles. Twenty horses were divided into two groups each of 10 animals. Horses in group 1 were treated with 0.2 mg/kg ivermectin (Eqvalan®) and group 2 horses received a combination of 0.2 mg/kg ivermectin + 2.5 mg/kg praziquantel (Equimax®). After treatment, in weeks 3, 5, 7, 9 and 11 individual faecal samples were collected and faecal egg counts (EPG) were determined using a modified McMaster method. The evaluation of drug efficacy was based on faecal egg count reduction test (FECRT). Both Eqvalan® and Equimax® were found to be highly effective (>97%) for a period of 7 weeks. From week 9 onwards, EPG values in both groups were tended to increase. Pre- and post-treatment faecal cultures showed that only small strongyles (Cyathostominae) were present. Adverse reactions to treatments were not observed. It is concluded that treatments of horses either with Eqvalan® or Equimax® for the prevention of strongylosis should be administered with intervals of 7 weeks.

Özet

Bu çalışmada Eqvalan® (ivermectin) ve Equimax® (ivermectin + praziquantel)'ın Strongylidae türleri ile doğal enfekte atlarda etkinliklerinin ve etki sürelerinin karşılaştırılması yapılmıştır. Bu amaçla, 20 at iki gruba ayrılmış, birinci gruptaki atlar 0.2 mğ/kg dozda ivermectin (Eqvalan®), ikinci gruptaki atlar ise 0.2 mg/kg ivermectin + 2.5 mg/kg praziquantel (Equimax®) kombinasyonu ile tedavi edilmişlerdir. Tedavi sonrası 3., 5., 7., 9. ve 11. haftalarda alınan dışkı numunelerinde McMaster yöntemiyle gram dışkıdaki yumurta sayıları (EPG) belirlenmiştir. İlaç etkinliği, dışkıda yumurta sayısı azalım testi (FECRT)'ne göre hesaplanmıştır. İki antelmentik de 7 hafta boyunca >%97 etki göstermiş, 9. haftadan itibaren ise EPG değerleri artmaya başlamıştır. Tedavi öncesi ve sonrası yapılan dışkı kültürlerinden elde edilen 3.dönem larvaların Cyathostominae alt familyasına ait olduğu teşhis edilmiştir. İlaç uygulanan hayvanların hiçbirinde yan etki gözlenmemiştir. Sonuç olarak, atları Strongylidae enfeksiyonlarından koruma amaçlı yapılacak Eqvalan® veya Equimax® tedavileri 7 hafta arayla uygulanmalıdır.

🔖

Cite This Article

ÇIRAK, V. Y., GÜLEĞEN, E., YILDIRIM, F., DURMAZ, M. (2003). Efficacy of eqvalan (ivermectin) and equimax (ivermectin+praziquantel) against strongylidae species in naturally infected horses. Uludağ Üniversitesi Veteriner Fakültesi Dergisi, Cilt: 22 - Sayı: 1, 45–49. https://ajindex.com/articles/326330

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (13)

  1. Akkaya H, Horoz H, Vuruşaner C. Strongylus spp. ve Parascaris equorum ile invaze yarış atlarının (Safkan İngiliz) Febantel (Rintal®) ile tedavisi ve Strongylus larvalarının orantılarının tespiti.T Parazitol Derg 1998
  2. Bauer C, Merkt JC, Janke-Grimm G, Bürger H-J. Prevalence and control of benzimidazole-resistant small strongyles on German thoroughbred studs. Vet Parasitol 1986
  3. Bauer C. Praktikum der Veterinärmedizinischen Parasitologie. Ferbersche Universitätsbuchhandlung, Giessen, 1990. 4.Boersema JH, Eysker M, Van der Aar WM. The reappearance of strongyle eggs in the faeces of horses after treatment with moxidectin. Vet Quart 1998
  4. chapman mr, french dd, monahan cm, klei tr. Identification and characterization of a pyrantel pamoate resistant cyathostome population. Vet Parasitol 1996
  5. Čorba J, PrasliČka J, Várady M, AndraŠko H, HolakovskỲ P. Efficay of Moxidectin 2% Equine Gel and Eqvalan 1% Paste against naturally acquired internal parasite infections in horses. Helminthologia 1995
  6. Coşkun ŞZ, Tınar R, Akyol ÇV, Özdemİr T. Atlarda bağırsak nematodları ve Gasterophilus spp.larvalarına Neguvon’un etkisi. T Parazitol Derg 1995
  7. Coşkun ŞZ, Tınar R, Aydın L, Akandır M. Atların Strongylidae enfeksiyonlarında albendazol, febantel, ve luxabendazolün etkisi. Uludağ Üniv Vet Fak Derg 1992
  8. Demeulenaere D, Vercruysse J, Dorny P, Claerebout E. Comparative studies of ivermectin and moxidectin in the control of naturally acquired cyathostome infections in horses. Vet Rec 1997
  9. Duncan JL, Abbott EM, Arundel JH, Eysker M, KleI TR, Krecek RC, Lyons ET, ReInemeyer C, Slocombe JOD. World association for the advancement of veterinary parasitology (WAAVP): second edition of guidelines for evaluating the efficacy of equine anthelmintics. Vet Parasitol 2002
  10. Gülanber A, Tüzer E, Gargılı A, Toparlak M, Efil I, Keleş V, Ulutaş M. Efficacy of moxidectin against strongylin nematodes in naturally infected horses. Tr J Vet Anim Sci 1998
  11. Herd RP, Gabel AA. Reduced efficacy of anthelmintics in young compared with adult horses. Equine Vet J 1990
  12. KleI TR, Rehbein S, Visser M, Langholff WK, Chapman MR, French DD, Hanson P. Re-evaluation of ivermectin efficacy against equine gastrointestinal parasites. Vet Parasitol 2001
  13. langrovÁ ı, borovskỲ m, jankovskÁ ı, navrÁtıl j, slavÍk v. The benzimidazole resistance