Journals / Ulusal Travma ve Acil Cerrahi Dergisi / 2017 / Cilt: 23 - Sayı: 2

Primary small intestinal non-Hodgkin lymphoma diagnosed after emergency surgery

Pages
128–133
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Mean follow-up time was 26 months (range: 1–69 months) and 5-year survival rate was 64.3%.CONCLUSION: Initial presentation of PGI NHL may be obstruction with or without perforation; clinicians and surgeons should keep this in mind while assessing patient with bowel obstruction, and particularly patient in fifth decade of life

📌 3 Key Takeaways

🎯
Objective & Hypothesis:BACKGROUND: The aim of this study was to investigate clinical manifestation, diagnosis, treatment, and prognosis of patients with primary gastrointestinal non-Hodgkin lymphoma (PGI NHL), whose initial presentation was bowel obstruction or perforation.METHODS: Data of patients who underwent surgical intervention due to radiological evidence of perforation or intestinal obstruction and were subsequently diagnosed with intestinal lymphoma at Baskent University hospitals between January 2007 and November 2014 were examined retrospectively.
📊
Key Findings & Data:Medical records, clinical history, symptoms, pathological reports, and treatment modalities were analyzed.RESULTS: Study population comprised 17 patients (8 male, 9 female) with PGI NHL and mean age of 52±20.2 years.
💡
Conclusion & Impact:Mean follow-up time was 26 months (range: 1–69 months) and 5-year survival rate was 64.3%.CONCLUSION: Initial presentation of PGI NHL may be obstruction with or without perforation; clinicians and surgeons should keep this in mind while assessing patient with bowel obstruction, and particularly patient in fifth decade of life
🔬Design:Research Article
📍Scope:2007 Verileri
⚙️Variables:Domain Parameters

Abstract

BACKGROUND: The aim of this study was to investigate clinical manifestation, diagnosis, treatment, and prognosis of patients with primary gastrointestinal non-Hodgkin lymphoma (PGI NHL), whose initial presentation was bowel obstruction or perforation.METHODS: Data of patients who underwent surgical intervention due to radiological evidence of perforation or intestinal obstruction and were subsequently diagnosed with intestinal lymphoma at Baskent University hospitals between January 2007 and November 2014 were examined retrospectively. Medical records, clinical history, symptoms, pathological reports, and treatment modalities were analyzed.RESULTS: Study population comprised 17 patients (8 male, 9 female) with PGI NHL and mean age of 52±20.2 years. Symptoms reported by the patients were abdominal pain, nausea, vomiting, weight loss, and loss of appetite. All 17 patients underwent surgical treatment; 12 also received postoperative chemotherapy. Most common pathological subtype was diffuse large B-cell lymphoma (70.5%). Mean follow-up time was 26 months (range: 1–69 months) and 5-year survival rate was 64.3%.CONCLUSION: Initial presentation of PGI NHL may be obstruction with or without perforation; clinicians and surgeons should keep this in mind while assessing patient with bowel obstruction, and particularly patient in fifth decade of life

🔖

Cite This Article

AVCI, T., YABANOĞLU, H., ARER, İ. M., KOÇER, N. E., ÇALIŞKAN, K., BÖRCEK, P., EKİCİ, Y. (2017). Primary small intestinal non-Hodgkin lymphoma diagnosed after emergency surgery. Ulusal Travma ve Acil Cerrahi Dergisi, Cilt: 23 - Sayı: 2, 128–133. https://ajindex.com/articles/323707

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (14)

  1. Gou HF, Zang J, Jiang M, Yang Y, Cao D, Chen XC. Clinical prognostic analysis of 116 patients with primary intestinal non-Hodgkin lymphoma. Med Oncol 2012;29:227–34
  2. Koch P, del Valle F, Berdel WE, Willich NA, Reers B, Hiddemann W, et al. Primary gastrointestinal non-Hodgkin’s lymphoma: I. Anatomic and histologic distribution, clinical features, and survival data of 371 patients registered in the German Multicenter Study GIT NHL 01/92. J Clin Oncol 2001;19:3861–73
  3. Yoon SS, Coit DG, Portlock CS, Karpeh MS. The diminishing role of surgery in the treatment of gastric lymphoma. Ann Surg 2004;240:28– 37
  4. Koniaris LG, Drugas G, Katzman PJ, Salloum R. Management of gastrointestinal lymphoma. J Am Coll Surg 2003;197:127–41
  5. Hwang HS, Yoon DH, Suh C, Park CS, Huh J. Intestinal diffuse large Bcell lymphoma: an evaluation of different staging systems. J Korean Med Sci 2014;29:53–60
  6. Radić-Kristo D, Planinc-Peraica A, Ostojić S, Vrhovac R, KardumSkelin I, Jaksić B. Primary gastrointestinal non-Hodgkin lymphoma in adults: clinicopathologic and survival characteristics. Coll Antropol 2010;34:413–7
  7. Howdle PD, Jalal PK, Holmes GK, Houlston RS. Primary small-bowel malignancy in the UK and its association with coeliac disease. QJM 2003;96:345–53
  8. Lee J, Kim WS, Kim K, Ko YH, Kim JJ, Kim YH, et al. Intestinal lymphoma: exploration of the prognostic factors and the optimal treatment. Leuk Lymphoma 2004;45:339–44
  9. Berney T, Delis S, Kato T, Nishida S, Mittal NK, Madariaga J, et al. Successful treatment of posttransplant lymphoproliferative disease with prolonged rituximab treatment in intestinal transplant recipients. Transplantation 2002;74:1000–6
  10. Hall CH Jr, Shamma M. Primary intestinal lymphoma complicating Crohn’s disease. J Clin Gastroenterol 2003;36:332–6
  11. Aydin I, Başkent A, Celik G, Aren A, Eren MZ, et al. A case of primary intestinal lymphoma associated with intestinal perforation. Ulus Travma Derg 2001;7:74–6
  12. Yokota T, Yamada Y, Murakami Y, Yasuda M, Kunii Y, Yamauchi H, et al. Abdominal crisis caused by perforation of ileal lymphoma. Am J Emerg Med 2002;20:136–7
  13. Ara C, Coban S, Kayaalp C, Yilmaz S, Kirimlioglu V. Spontaneous intestinal perforation due to non-Hodgkin’s lymphoma: evaluation of eight cases. Dig Dis Sci 2007;52:1752–6
  14. Huang Q, Chang KL, Gaal K, Arber DA. Primary effusion lymphoma with subsequent development of a small bowel mass in an HIV-seropositive patient: a case report and literature review. Am J