Journals / Uluslararası Hematoloji-Onkoloji Dergisi / 2012 / Cilt: 22 - Sayı: 4

Hipofiz adenomlarında stereotaktik radyocerrahi: Tek merkez deneyimi

Stereotactic radiosurgery in pituitary adenomas: A single center experience

Pages
255–260
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Treatment of pituitary adenomas using LINAC-based single dose SRS is safe and effective in improving local tumor and biochemical control.

📌 3 Key Takeaways

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Objective & Hypothesis:The aim of this study was to evaluate the efficiency of stereotactic radiosurgery (SRS) in the management of pituitary adenomas.
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Key Findings & Data:Between June 1998 and July 2011, 57 patients with pituitary adenomas were treated using SRS at our department.
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Conclusion & Impact:Treatment of pituitary adenomas using LINAC-based single dose SRS is safe and effective in improving local tumor and biochemical control.
🔬Design:Research Article
📍Scope:2011 Verileri
⚙️Variables:Domain Parameters

Abstract

The aim of this study was to evaluate the efficiency of stereotactic radiosurgery (SRS) in the management of pituitary adenomas. Between June 1998 and July 2011, 57 patients with pituitary adenomas were treated using SRS at our department. All patients underwent high-precision single dose SRS using a linear accelerator with 6-MV photons. Median follow-up time was 31.5 (3-92) months. Median age was 40 years (range: 19-57 years). Radiological tumor growth control was achieved in 48 patients (84.2%) (a decrease in tumor size in 25 patients and no change in tumor size in 23 patients). 13 patients with functioning adenomas had available biochemical follow-up and biochemical complete response was achieved in 8 (61.5%) of these 13 patients. Treatment of pituitary adenomas using LINAC-based single dose SRS is safe and effective in improving local tumor and biochemical control.

Özet

Bu çalışmanın amacı stereotaktik radyocerrahi’nin hipofiz adenomu manajmanındaki etkinliğinin değerlendirilmesidir. Kliniğimizde Haziran 1998 ile Temmuz 2011 tarihleri arasında hipofiz adenomlu 57 hasta stereotaktik radyocerrahi ile tedavi edilmiştir. Tüm hastalara lineer akseleratörde 6 MV fotonlarla tek dozda yüksek hassasiyetli stereotaktik radyocerrahi uygulanmıştır. Medyan takip süresi 31.5 ay (sınırlar: 3-92 ay) idi. Radyolojik tümör büyüme kontrolü 48 hastada (84.2%) sağlanmıştır (25 hastada tümör boyutunda küçülme, 23 hastada tümör boyutunda değişiklik yok). Biyokimyasal takibi mevcut olan fonksiyone adenomlu 13 hastadan 8’inde (%61.5) biyokimyasal tam cevap elde edilmiştir. Linak tabanlı tek doz stereotaktik radyocerrahi ile hipofiz adenomlarının tedavisi lokal tümör kontrolü ve biyokimyasal kontrolün iyileştirmesinde güvenli ve etkindir.

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Cite This Article

SÜRENKÖK, S., SAĞER, Ö., DİNÇOĞLAN, F., GAMSIZ, H., DEMİRAL, S., UYSAL, B., ŞİRİN, S., OYSUL, K., BEYZADEOĞLU, M. M. (2012). Hipofiz adenomlarında stereotaktik radyocerrahi: Tek merkez deneyimi. Uluslararası Hematoloji-Onkoloji Dergisi, Cilt: 22 - Sayı: 4, 255–260. https://ajindex.com/articles/323192

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