Journals / Uluslararası Hematoloji-Onkoloji Dergisi / 2008 / Cilt: 18 - Sayı: 3

Diffuse alveolar hemorrhage due to uncontrolled warfarin therapy: Case report

Kontrolsüz warfarin kullanımına bağlı gelişen yaygın alveoler hemoraji: Olgu sunumu

Pages
170–174
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We aimed to overview the diagnosis and treatment choices of DAH.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Warfarin; one of the most common oral anticoagülant drug is used for treatment of thromboembolic events and also for prevention of thromboembolic complications in atrial fibrillation and other cardiovascular diseases.
📊
Key Findings & Data:The most important adverse effect is hemorrhage.
💡
Conclusion & Impact:We aimed to overview the diagnosis and treatment choices of DAH.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Yaşlı · Kanama · Erkek

Abstract

Warfarin; one of the most common oral anticoagülant drug is used for treatment of thromboembolic events and also for prevention of thromboembolic complications in atrial fibrillation and other cardiovascular diseases. The most important adverse effect is hemorrhage. Diffuse alveolar hemorrhage (DAH) is a rare complication of warfarin dependent hemorrhages. Nevertheless, it is a life-threatening disease if the treatment was not started as soon as possible. Our case represents DAH as a complication of uncontrolled warfarin therapy. We aimed to overview the diagnosis and treatment choices of DAH.

Özet

Oral antikoagülan bir ilaç olan warfarin tromboembolik olaylarda tedavi amacıyla yaygın olarak kullanılırken, aynı zamanda atriyal fibrilasyon ve diğer kardiyovasküler hastalıklarda tromboemboliyi önlemek için de kullanılmaktadır. Warfarin tedavisinin en önemli yan etkisi kanamadır. Diffüz alveoler hemoraji (DAH), warfarin kullanımına bağlı kanamalar arasında nadir görülen bir komplikasyondur. Bununla beraber erken tanı konulup tedavi edilmediği takdirde hayatı tehdit eden bir durumdur. Bu olgu sunumunda kontrolsüz warfarin kullanımının bir komplikasyonu olarak ortaya çıkan DAH ve DAH’nin tanı ve tedavisi ile ilgili literatür bilgilerinin gözden geçirilmesi amaçlanmıştır.

🔖

Cite This Article

AKAGÜN, T., GÜNGÖR, E., AKDOĞAN, E., BÜLBÜL, Y., SÖNMEZ, M. (2008). Diffuse alveolar hemorrhage due to uncontrolled warfarin therapy: Case report. Uluslararası Hematoloji-Onkoloji Dergisi, Cilt: 18 - Sayı: 3, 170–174. https://ajindex.com/articles/323028

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (11)

  1. Hirsh J, Dalen JE, Anderson DR et al. Oral anticogulants: mechanism of action, clinical effectiveness, and optimal therapeutic range. Chest 119: 8-21, 2001
  2. Deitcher S, Rodgers G. Thrombosis and antithrombotic therapy. Wintrobe’s Clinical Hematology. Lippincott Williams-Wilkins, 2004: 1713-1758
  3. Erdoğan D, Kocaman O, Oflaz H, Goren T. Alveolar hemorrhage associated with warfarin therapy: a case report and literature review. Int J Cardiovasc Imaging 20: 155-159, 2004
  4. Nural MS, Baydın A, Karataş AD, Elmalı M. Yüksek doz warfarin kullanımı sonucu gelişen yaygın alveoler hemoraji. Toraks Dergisi 7: 68-71, 2006
  5. Screiber J, Knolle J, Kachel R, Schuck R. Differential diagnosis of diffuse pulmonary haemorrhage. Pneumologie 60: 347-54, 2006
  6. Specks U. Diffuse alveolar hemorrhage syndromes. Curr Opin Rheumatol 13: 12-7, 2001
  7. Heslet L, Nielsen JD, Levi M, et al. Successful pulmonary administration of activated recombinant factor VII in diffuse alveolar hemorrhage. Critical Care 10: R177, 2006
  8. Primack SL, Miller RR, Müller NL. Diffuse pulmonary hemorrhage: Clinical, pathologic, and imaging featuras. AJR 164: 295-300, 1995
  9. Cordier JF. Alveolar hemorrhage. In Grassi C. Pulmonary Diseases. McGraw-Hill Co, 1999:253-257
  10. Cheah FK, Sheppard MN, Hansell DM. Computed tomography of diffuse pulmonary hemorrage with pathological correlation. Clin Radiol 48: 89-93, 1993
  11. Oymak S, Tokgöz B, Akgün H ve ark. Alveoler hemorajik sendromlar- Klinik, patolojik ve radyolojik özellikler: Onbir olgu analizi. Toraks Dergisi 3:52-58, 2002.