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Journals / Uzmanlık Sonrası Eğitim ve Güncel Gelişmeler Dergisi / 2007 / Cilt: 4 - Sayı: 2

Qualitative and quantitative doppler analysis of umbilical artery flow velocity for prediction of neonatal thrombocytopenia

Neonatal trombositopeniyi öngörmede umbilikal doppler akım hızının niteliksel ve niceliksel kullanımı

RAGIP ATAKAN AL
ETHEM SERDAR YALVAÇ
Cem BAYKAL
Ömer KANDEMİR
Erol AKKÖK
İsmail DÖLEN
Pages
91–95
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Quantitative analysis of umbilical artery flow pattern does not improve prediction of neonatal thrombocytopenia compared qualitative analysis of umbilical artery flow pattern.

📌 3 Key Takeaways

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Objective & Hypothesis:To compare quantitative and qualitative doppler analysis of umbilical artery for prediction of neonatal thrombocytopenia in fetuses with intrauterine growth restriction.
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Key Findings & Data:Between 2002-2004, all pregnant women with normal fetal anatomy, estimated fetal weight below 3rd percentile, umbilical artery pulsatility index > 2 SD, live fetus and neonatal blood results available Interventions.
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Conclusion & Impact:Quantitative analysis of umbilical artery flow pattern does not improve prediction of neonatal thrombocytopenia compared qualitative analysis of umbilical artery flow pattern.
🔬Design:Research Article
📍Scope:2002-2004 Verileri
⚙️Variables:Umbilikal arterler · Trombositopeni · neonatal alloimmün

Abstract

Objective. To compare quantitative and qualitative doppler analysis of umbilical artery for prediction of neonatal thrombocytopenia in fetuses with intrauterine growth restriction. Design. Retrospective analysis Setting. Hospital Patients. Between 2002-2004, all pregnant women with normal fetal anatomy, estimated fetal weight below 3rd percentile, umbilical artery pulsatility index > 2 SD, live fetus and neonatal blood results available Interventions. None Main outcome measures. Neonatal thrombocytopenia Results. Umbilical artery absent or reversed end diastolic flow pattern has a sensitivity of %90 and a false positive ratio of % 27.3 for prediction neonatal thrombocytopenia (area under curve.817 %95 [CI.736-.882], p<.001). With a cutoff umbilical artery PI greater than 1.53 as a predictor of neonatal thrombocytopenia, sensitivity and false positive ratio were %100 and % 36.4 respectively (.898 [%95 CI.83-.95] p<.001). Area under curve in ROC analysis were similar in both test (p=.198). Conclusions. Quantitative analysis of umbilical artery flow pattern does not improve prediction of neonatal thrombocytopenia compared qualitative analysis of umbilical artery flow pattern.

Özet

Objektif: İntrauterin fetal gelişme kısıtlılığı olgularında, neonatal trombositopeniyi öngörmede umbilikal arter Dopplerinin niceliksel ve niteliksel olarak kullanımını karşılaştırmak Planlama: Retrospektif çalışma Ortam: Hastane Hastalar: 2002-2004 tarihleri arasında doğum yapmış, fetal anatomisi normal, tahmini fetal ağırlığı 3 persentil altında öngörülen, umbilikal arter pulsatilite indeksi ölçümü 2 standart sapmanın üstünde, canlı doğan, neonatal kan sonuçları mevcut gebeler Girişim: Yok Değerlendirme parametreleri: Neonatal trombositopeni Sonuç: Umbilikal arter diastol sonu akımı kaybı yada ters akım varlığının neonatal trombositopeniyi öngörme sensitivitesi %90, yanlış pozitiflik oranı % 27,3 olarak hesaplandı (eğri altında kalan alan 0,817 %95 [güven aralığı {CI} 0,736-0,882], p<0,001), Umbilikal arter Doppler akım hızı niceliksel olarak kullanıldığında, PI'nin 1,53 eşik değeri için sensivite %100 yanlış pozitiflik oranı % 36,4 hesaplandı (eğri altında kalan alan 0,898 [%95 CI 0,83-0,95 p<0,001]). Eğri altında kalan alan her iki yöntemde de benzer bulundu (p=0,198). Yorum: Neonatal trombositopeniyi öngörmede Umbilikal arter Doppler akım hızının niceliksel kullanımının niteliksel kullanımına üstünlüğü yoktur.

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Cite This Article

AL, R. A., YALVAÇ, E. S., BAYKAL, C., KANDEMİR, Ö., AKKÖK, E., DÖLEN, İ. (2007). Qualitative and quantitative doppler analysis of umbilical artery flow velocity for prediction of neonatal thrombocytopenia. Uzmanlık Sonrası Eğitim ve Güncel Gelişmeler Dergisi, Cilt: 4 - Sayı: 2, 91–95. https://ajindex.com/articles/320551

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References (14)

  1. Kaufmann P, Black S, Huppertz B. Endovascular trophoblast invasion: implications for the pathogenesis of intrauterine growth retardation and preeclampsia. Biol Reprod 2003;69:1-7
  2. Kingdom JC, Burrell SJ, Kaufmann P. Pathology and clinical implications of abnormal umbilical artery Doppler waveforms. Ultrasound Obstet Gynecol 1997; 9:271-86
  3. Wilcox GR, Trudinger BJ. Fetal platelet consumption: a feature of placental insufficiency. Obstet Gynecol 1991; 77:616-21
  4. Baschat AA, Gembruch U, Reiss I, Gortner L, Weiner CP, Harman CR. Absent umbilical artery endiastolic velocity in growth- restricted fetuses: a risk factor for neonatal thrombocytopenia. Obstet Gynecol 2000; 96:162-6
  5. Kush ML, Gortner L, Harman CR, Baschat AA. Sustained hematological consequences in the first week of neonatal life secondary to placental dysfunction. Early Hum Dev 2006;82: 67-72
  6. Davies N, Snijders R, Nicolaides KH. Intra uterine starvation and fetal leucocyte count. Fetal Diagn Ther 1991; 6:107-12
  7. Snijders RJ, Abbas A, Melby O, Ireland RM, Nicolaides KH. Fetal plasma erythropoietin concentration in severe growth retardation. Am J Obstet Gynecol 1993; 168:615-9
  8. Wilcox GR, Trudinger BJ, Cook CM, Wilcox WR, Connelly AJ. Reduced fetal platelet counts in pregnancies with abnormal Doppler umbilical flow waveforms. Obstet Gynecol 1989;7 639-43
  9. Morrow RJ, Adamson SL, Bull SB, Ritchie JW. Effect of placental embolization on the umbilical arterial velocity waveform in fetal sheep. Am J Obstet Gynecol 1989; 161:1055-60
  10. Trudinger B, Song JZ, Wu ZH, Wang J. Placental insufficiency is characterized by platelet activation in the fetus. Obstet Gynecol 2003; 101:975-81
  11. Yagel S, Anteby EY, Shen O, Cohen SM, Friedman Z, Achiron R. Placental blood flow measured by simultaneous multigate spectral Doppler imaging in pregnancies complicated by placental vascular abnormalities. Ultrasound Obstet Gynecol 1999;14:262-6
  12. Baschat AA, Gembruch U, Reiss I, Gortner L, Harman CR, Weiner CP. Neonatal nucleated red blood cell counts in growth- restricted fetuses: relationship to arterial and venous Doppler studies. Am J Obstet Gynecol 1999; 181:190-5
  13. Bernstein PS, Minior VK, Divon MY. Neonatal nucleated red blood cell counts in small for gestational age fetuses with abnormal umbilical artery Doppler studies. Am J Obstet Gynecol 1997; 177:1079-84
  14. Weiner CP. The relationship between the umbilical artery systolic/ diastolic ratio and umbilical blood gas measurements