Journals / Selçuk Tıp Dergisi / 2004 / Cilt: 20 - Sayı: 3

Myocardial performance index in children with secundum atrial septal defect

Sekundum atriyal septal defektli çocuklarda miyokard performans indeksi

Pages
109–114
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

This study documents that the MPI is a quantitative mea¬sure of ventricular function that is appears to be relatively independent of changes in preload.

📌 3 Key Takeaways

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Objective & Hypothesis:Quantitative assessment of ventricular function in patients with congenital heart disease is often challenging due to distorted ventricular geometry.
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Key Findings & Data:A myocardial performance index ( MPI) has been reported in adults and children that is a Doppler-derived non-geometric measure of ventricular function.
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Conclusion & Impact:This study documents that the MPI is a quantitative mea¬sure of ventricular function that is appears to be relatively independent of changes in preload.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Kalp septal defektleri · atrial · Çocuk

Abstract

Quantitative assessment of ventricular function in patients with congenital heart disease is often challenging due to distorted ventricular geometry. A myocardial performance index ( MPI) has been reported in adults and children that is a Doppler-derived non-geometric measure of ventricular function. The MPI measures the ratio of isovolumic time intervals to ventricular ejection time. The effects of altered ventricular preload orafterload on the MPI have yet to be determined. This study was designed to determine the impact of altered preload on left and right ventricular MPI in the clinical setting of atrial septal defect (ASD j. The left and right ventricular MPI were measured in 17 patients with ASD( ages 6 to 148 months, median 24 months j, and 24 normal children/ages 3 to 160 months, median 17 months). In patients with ASD and control groups, the left ventricular MPI was 0.38±0.16 and 0.32±0.09, and the right ven¬tricular MPI was 0.24±0.15 and 0.20+0.08 respectively. No significant change in the left and right ventricular MPI was seen in patients with atrial septal defect and control groups. This study documents that the MPI is a quantitative mea¬sure of ventricular function that is appears to be relatively independent of changes in preload.

Özet

Doğuştan kalp hastalığı olan hastalarda ventrikül geometrisi bozulacağı için ventrikül fonksiyonlarını değerlendirmede bazı zorluklar olabilmektedir. Ventrikül fonksiyonlarını değerlendirmede Doppler eko yöntemi ile elde edilen ve ventrikülün geometrik şekline bağımlı olmayan miyokard performans indeksi erişkin ve çocuklarda araştırılarak kullanılmaya başlanmıştır. Miyokard performans indeksi izovolumik zaman aralıklarının ventrikül ejeksiyon zamanına bölünmesi ile elde edilir. Ventriküllerin ön ve art yük değişikliklerinde bu indeksin nasıl etkilendiği araştırılmalıdır. Bu çalışma atriyal septal defektin (ASD j neden olduğu ön yük değişikliklerinde sağ ve sol ventriküler miyokard performans indeksinin nasıl etkilendiğini araştırmak amacı ile planlandı. Yaşları 6 ay ile 148 ay arasında (ortanca 24 ay) 17 ASD' li ve yaşları 3 ay ile 160 ay arasında (ortanca 17 ay) 24 normal çocukta sol ve sağ ventrikül için miyokard performans indeksi ölçüldü. Sol ventrikül için miyokard performans indeksi ASD ve kontrol grubunda sırası ile 0.38+0.16 ve 0.32+0 09 iken sağ ventrikül için miyokard performans indeksi sırası ile 0.24±0.15 ve 0.20±0.08 bulundu. Gruplar arasında sol ve sağ ventrikül miyokard performans indeksleri yönünden istatiksel açıdan anlamlı bir fark yoktu (p < 0.05 /. Bu çalışma ile ventrikül fonksiyonlarını ölçmeye yarayan miyokard performans indeksinin ASD'li hastalarda ön yük değişikliklerinden etkilenmediği gösterildi.

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Cite This Article

BAYSAL, T., ORAN, B., DOĞAN, M., ÇİMEN, D., KARAASLAN, S. (2004). Myocardial performance index in children with secundum atrial septal defect. Selçuk Tıp Dergisi, Cilt: 20 - Sayı: 3, 109–114. https://ajindex.com/articles/319229

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