Journals / TSK Koruyucu Hekimlik Bülteni / 2012 / Cilt: 11 - Sayı: 6

The Value of Naproxen Test as a Diagnostic Method to Differentiate Cause of Fever

Ateşin Ayırıcı Tanısında Tanı Yöntemi Olarak Naproksen Testinin Değeri

Pages
779–781
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

CONCLUSION: This study clearly showed that the naproxen test cannot be relied upon to guide diagnostic decision making in patients with fever unknown origin.

📌 3 Key Takeaways

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Objective & Hypothesis:AIM: Fever of whatever etiology still remains a perplexing problem to both clinicians and investigators.
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Key Findings & Data:RESULTS: Infectious diseases etiology was detected at 15 patients. 12 and 3 of them responded to naproxen test at the first and second days respectively.
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Conclusion & Impact:CONCLUSION: This study clearly showed that the naproxen test cannot be relied upon to guide diagnostic decision making in patients with fever unknown origin.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

AIM: Fever of whatever etiology still remains a perplexing problem to both clinicians and investigators. Increasingly, its role in connective tissue diseases, malignancies and other inflammatory disorders is slowly supplanting the exclusivity of the symptom to just infectious conditions. This study aims to determine the sensitivity of the naproxen test and the diagnostic value in patients with a prolonged febrile illness. METHOD: We evaluated twenty patients retrospectively had been administered the naproxen test. Fever lysis after or within the time frame of drug administration was interpreted as a infectious or an infectious condition. RESULTS: Infectious diseases etiology was detected at 15 patients. 12 and 3 of them responded to naproxen test at the first and second days respectively. Two of non-infectious etiology patients remained unanswered. CONCLUSION: This study clearly showed that the naproxen test cannot be relied upon to guide diagnostic decision making in patients with fever unknown origin.

Özet

AMAÇ: Ateş etiyolojisini tespit etmek hem klinisyenler ve hem de araştırmacılar için hala sorun olmaya devam etmektedir. Giderek artan, bağ dokusu hastalıkları, kanserler ve diğer inflamatuar hastalıklar enfeksiyöz hastalıkların ateş etiyolojisindeki seçkin yerini yavaş yavaş almaya başlamıştır. Bu çalışmayla uzamış ateşi olan hastalarda naproksen testinin hassasiyetini ve tanısal değerini tespit etmek amaçlanmıştır. YÖNTEM: Naproksen testi uygulanmış hastalarda ateşin düşüşü enfeksiyoz veya non-enfeksiyoz durumlara göre değerlendirildi. BULGULAR: Enfeksiyon etiyolojisi 15 hastada tespit edildi. Bunların 12'si ilk 3'ü 2. gün naproksen testine yanıt verdi. Non enfeksiyöz hastaların ikisi naproksen testine yanıt vermedi. SONUÇ: Bu çalışma naproksen testinin hastalarda ateş etiyolojisini araştırmak amacıyla güvenilir bir tanı yöntemi olarak kullanılamayacağını gösterdi.

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Cite This Article

COŞKUN, Ö., KARAKAŞ, A., SAVAŞCI, Ü., EYİGÜN, C. P. (2012). The Value of Naproxen Test as a Diagnostic Method to Differentiate Cause of Fever. TSK Koruyucu Hekimlik Bülteni, Cilt: 11 - Sayı: 6, 779–781. https://ajindex.com/articles/309728

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References (6)

  1. Chang JC, Gross HM. Utility of naproxen in the differential diagnosis of fever of undetermined origin in patients with cancer. Am J Med. 1984; 76(4): 597-603
  2. Tsavaris N, Zinelis A, Karabelis A, et al. A randomized trial of the effect of three non-steroid anti-inflammatory agents in ameliorating cancerinduced fever. J Intern Med. 1990; 228(5): 451- 455
  3. Economos K, Lucci JA, Richardson B, Yazigi R, Miller DS. The effect of naproxen on fever in patients with advanced gynecologic malignancies. Gynecol Oncol. 1995; 56(2): 250- 254
  4. Plaisance KI, Mackowiak PA. Antipyretic therapy: physiologic rationale, diagnostic implications, and clinical consequences. Arch Intern Med. 2000; 160(4): 449-456
  5. Arnow PM, Flaherty JP. Fever of unknown origin. Lancet. 199; 350(9077): 575-580
  6. Mackowiak PA. Temperature Regulation and the Pathogenesis of Fever In: Mandell GL, Bennett JE, Dolin R, (eds). Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases. 7 ed: Churchill Livingstone Philadelphia USA, 2009, p. 765-778.