Journals / Retina-Vitreus / 2010 / Cilt: 18 - Sayı: 1

The Effect of Cryotherapy and Laser Phohotocoagulation Therapy in the Treatment of Coats' Disease

Coats Hastalığında Kriyoterapi ve Lazer Fotokoagülasyon Tedavisinin Etkinliği

Pages
46–51
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Key Words: Coats' disease, cryotherapy, lazer photocoagulation, intravitreal bevacizumab

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: To evaluate the effectiveness of cryotherapy and lazer photocoagulation therapy in Coat's disease.Materials and Methods: Five eyes of five patients with Coats' disease who had at least 2 years of follow up after their initial evaluation were included in this study.
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Key Findings & Data:All patients had macular involvement with exudate, two of the 5 patients had subtotal retinal detachment and subretinal fibrosis.
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Conclusion & Impact:Key Words: Coats' disease, cryotherapy, lazer photocoagulation, intravitreal bevacizumab
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Purpose: To evaluate the effectiveness of cryotherapy and lazer photocoagulation therapy in Coat's disease.Materials and Methods: Five eyes of five patients with Coats' disease who had at least 2 years of follow up after their initial evaluation were included in this study. All patients had macular involvement with exudate, two of the 5 patients had subtotal retinal detachment and subretinal fibrosis. Patients with total retinal detachment were excluded. Treatment modalities consisted of cryotherapy with and without indirect diode lazer photocoagulation. Intravitreal bevacizumab injection was performed in one eye.Results: Five patients were male. At presentation the average age was mean 5.2 years (range 1.2-11 years). The mean number of treatment required was 3 . Four of five eyes achieved anatomic success with complete resolution of the telangiectasis and exudations. Final visual acuity was 2/10 or better in 2 eyes, finger counting in one, hand motion in one and no light perception in one. The mean follow-up was 3.6 years (2.1-4.8 years). One of the treated patients had recurrences.Conclusions: Cryotherapy and lazer photocoagulation therapy can anatomically improve the eye with Coats' disease but the visual outcome can be poor. Coats disease can recur so long follow-up period is necessary. Key Words: Coats' disease, cryotherapy, lazer photocoagulation, intravitreal bevacizumab

Özet

Amaç: Coats hastalığının tedavisinde kriyoterapi ve lazer fotokoagülasyonunun etkinliğini değerlendirmek.Gereç ve Yöntem: Çalışmaya tanı konduktan sonra en az 2 yıl takip edilen 5 Coats hastasının 5 gözü alındı. Gözlerin tümünde makulayı da içeren yoğun lipid eksüdasyon vardı. İki gözde lipid eksüdasyona ek olarak subtotal eksüdatif retina dekolmanı ve retina altı fibrozis mevcuttu. Total retina dekolmanı olan hastalar çalışmaya alınmadı. Tedavide kriyoterapi ve indirekt diod lazer fotokoagülasyon tedavisi uygulandı. Bir göze intravitreal bevacizumab enjeksiyonu yapıldı.Bulgular: Beş hasta da erkekti. Tanı konduğunda ortalama yaş 5.2 yıl (1.2-11 yıl arası) idi. Ortalama tedavi sayısı 3 (2-4 arası) idi. Tedavi ile 5 gözün 4'ünde telenjiektazilerin ve eksüdasyonların tamamen gerilemesi ile anatomik başarı sağlandı. Son görme keskinliği 2 gözde 2/10 ve üzerinde, birinde parmak sayma, birinde el hareketleri düzeyindeydi. Bir gözde ışık hissi yoktu. Hastalar ortalama 3.6 yıl (2.1-4.8 yıl arası) takip edildiler. Hastaların birinde takipler sırasında nüks görüldü.Sonuç: Coats hastalığında, kriyoterapi ve lazer fotokoagülasyon tedavisi ile anatomik olarak başarılı sonuçlar alınabilir ancak görme prognozu iyi olmayabilir. Coats hastalığı nüksedebilir bu nedenle uzun süre takip önemlidir

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Cite This Article

EROL, N., TOPBAŞ, S. (2010). The Effect of Cryotherapy and Laser Phohotocoagulation Therapy in the Treatment of Coats' Disease. Retina-Vitreus, Cilt: 18 - Sayı: 1, 46–51. https://ajindex.com/articles/308057

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