Journals / Retina-Vitreus / 2016 / Cilt: 24 - Sayı: 1

The Assessment of Retinal Nerve Fiber Layer Thickness in Children with Iron Deficiency Anemia

Demir Eksikliği Anemili Çocuk Hastalarda Retina Sinir Lifi Tabakası Kalınlığının Değerlendirilmesi

Pages
37–40
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

There were positive correlation between hemoglobin, iron, and ferritin levels and RNFL thickness.

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: To determine changes in retinal nerve fiber layer (RNFL) thickness in children with iron deficiency anemia (IDA).Material and Methods: The study was included 38 healthy children and 44 patients with IDA.
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Key Findings & Data:Four quadrants (superior, inferior, nasal and temporal) and average RNFL thickness in the all patients were evaluated with spectral domain optical coherence tomography.Results: There were no statistically significant differences between the two groups in terms of central corneal thickness, visual acuity and intraocular pressure (p>0.05).
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Conclusion & Impact:There were positive correlation between hemoglobin, iron, and ferritin levels and RNFL thickness.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Purpose: To determine changes in retinal nerve fiber layer (RNFL) thickness in children with iron deficiency anemia (IDA).Material and Methods: The study was included 38 healthy children and 44 patients with IDA. The hemoglobin, iron, and ferritin levels and iron binding capacity were recorded. All participants underwent a complete ophthalmologic examination, including visual acuity, intraocular pressure and central corneal thickness measurements. Four quadrants (superior, inferior, nasal and temporal) and average RNFL thickness in the all patients were evaluated with spectral domain optical coherence tomography.Results: There were no statistically significant differences between the two groups in terms of central corneal thickness, visual acuity and intraocular pressure (p>0.05). Although detected the significantly thinner RNFL in the avarage and superior, and inferior quadrant (p=0.035, p<0.001 and p=0.004 respectively) in the IDA group, there were no statistically significant differences in the temporal and nasal RNFL thickness compared to the control group. In the IDA group, there were significant correlations between inferior quadrant RNFL thickness and hemoglobin (r=0.235; p=0.042), and between avarage RNFL thickness and serum iron (r=0.312; p=0.014) and ferritin concentrations (r=0.241; p=0.012). Conclusion: The RNLF thickness decreased in the children with IDA. There were positive correlation between hemoglobin, iron, and ferritin levels and RNFL thickness.

Özet

Amaç: Demir eksikliği anemisi (DEA) bulunan çocuk hastalarda retina sinir lifi tabakası (RSLT) kalınlığında değişiklik olup olmadığının belirlenmesi.Gereç ve Yöntem: Çalışmaya 44 DEA hastası ile 38 sağlıklı çocuk alındı. Hemoglobin, demir, demir bağlama kapasitesi ve ferritin düzeyleri kaydedildi. Tüm olguların göz içi basıncı, görme keskinliği ve santral korneal kalınlık ölçümlerini içeren ayrıntılı oftalmolojik muayeneleri yapıldı. Spectral domain optik koherens tomografi cihazı ile tüm hastaların dört bölgeli (üst, alt, nazal ve temporal) ve ortalama RSLT kalınlıkları değerlendirildi.Bulgular: Santral korneal kalınlık, görme keskinliği ve göz içi basınç değerleri açısından iki grup arasında istatistiksel olarak anlamlı fark saptanmadı (p>0.05). DEA hastalarında üst, alt ve ortalama RSLT kalınlıklarında kontrol grubuna göre anlamlı düzeyde azalma saptanırken (sırasıyla p=0.035, p<0.001 ve p=0.004), temporal ve nazal RSLT kalınlıklarında istatistiksel olarak anlamlı fark saptanmadı. DEA grubunda, alt kadran RSLT kalınlıkları ile hemoglobin arasında (r=0.235; P=0.042) ve ortalama RSLT kalınlıkları ile serum demir (r=0.312; P=0.014) ve ferritin (r=0.241; P=0.012) düzeyleri arasında pozitif korelasyon saptandı. Sonuç: DEA bulunan çocuklarda RSLT kalınlıklarının azaldığı gözlendi. Hemoglobin, demir ve ferritin düzeyleri ile RSLT kalınlıkları arasında pozitif korelasyon saptandı.

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Cite This Article

ŞİMŞEK, A., TEKİN, M., BİLEN, A., BİLAK, Ş., ÇİFTÇİ, S., TURGUT, M. (2016). The Assessment of Retinal Nerve Fiber Layer Thickness in Children with Iron Deficiency Anemia. Retina-Vitreus, Cilt: 24 - Sayı: 1, 37–40. https://ajindex.com/articles/308014

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