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Journals / Retina-Vitreus / 2003 / Cilt: 11 - Sayı: 1

Selective intraarterial fibrinolytic treatment for acute central retinal artery occlusions

Akut santral retinal arter tıkanıklarında selektif intraarteriel fibrinolitik tedavi

Şengül ÖZDEK
Sergin AKPEK
Gökhan GÜRELİK
Beyhan GÖL
Erhan ILGIT
Berati HASANREİSOĞLU
Pages
30–35
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Possible complications, however, should be kept in mind during patient selection.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Purpose: To determine the effectiveness of selective intraarterial fibrinolytic treatment which is a new alternative method for the treatment of acute central retinal artery occlusions.
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Key Findings & Data:Materials and Methods: Four patients with an acute visual loss starting 7 to 16 hours before were included in the study.
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Conclusion & Impact:Possible complications, however, should be kept in mind during patient selection.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:İzleme çalışmaları · Fibrinolitik ajanlar · Trombolitik tedavi

Abstract

Purpose: To determine the effectiveness of selective intraarterial fibrinolytic treatment which is a new alternative method for the treatment of acute central retinal artery occlusions. Materials and Methods: Four patients with an acute visual loss starting 7 to 16 hours before were included in the study. Visual acuities were less than counting fingers form 1 meter in all of them. Pre- and post-treatment fluorescein angiography was performed in all of the cases. Coaxial catheter sistem was used to reach the ophthalmic artery via femoral artery and fibrinolytic agents (tPA and urokinase) were infused slowly. Results: Patients were followed up for 26 months. Visual acuities increased in all cases except one. One case experienced transient hemiplegia starting on second day of therapy which resolved within a week. Conclusions: Selective intraarterial fibrinolytic therapy is an alternative method for the treatment of acute central retinal artery occlusion cases especially when applied at an early stage. Possible complications, however, should be kept in mind during patient selection.

Özet

Amaç: Akut santral retinal arter tıkanıklığında yeni ve alternatif bir tedavi yöntemi olarak selektif intraarteriyel fibrinolitik tedavi etkinlik ve sonuçlarının değerlendirilmesi Gereç ve Yöntem: Görme kaybı başlangıcından itibaren 7-16 saat içinde başvuran 4 olgu çalışmaya dahil edildi. Görme düzeyleri tüm hastalarda 1mps idi. Tüm olgulara tedavi öncesi ve sonrası flöresein anjiografi çekildi. Koaksiyel kateter sistemi ile femoral arterden oftalmik artere ulaşıldı ve fibrinolitik ajanlar (urokinaz veya tPA) yavaş infüzyon şeklinde verildi. Bulgular: Olgular ortalama 26 ay süreyle takip edildiler. Bir olgu haricinde tüm olgularda görme düzeyinde artış oldu. Bir olguda trombolitik tedavi sonrası 2. gün başlayan ve bir haftada düzelen hemipeji oldu. Sonuç: Selektif intraarteriyel fibrinolitik tedavi özellikle erken dönemde başvuran akut santral retinal arter tıkanıklıklarının tedavisinde kullanılabilecek alternatif bir tedavi yöntemidir. Fakat muhtemel komplikasyonlar nedeniyle hasta seçim kriterlerine dikkatle uyulmalıdır.

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Cite This Article

ÖZDEK, Ş., AKPEK, S., GÜRELİK, G., GÖL, B., ILGIT, E., HASANREİSOĞLU, B. (2003). Selective intraarterial fibrinolytic treatment for acute central retinal artery occlusions. Retina-Vitreus, Cilt: 11 - Sayı: 1, 30–35. https://ajindex.com/articles/307955

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